Patents by Inventor Bryan Whitson

Bryan Whitson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Perforated submucosal tissue graft constructs
    Patent number: 5997575
    Abstract: A perforated unitary multi-laminar tissue graft construct and method for preparing such construct is described. The method comprises overlapping strips of submucosa tissue with other strips of submucosal tissue, compressing at least the overlapped portions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets, and perforating the resulting unitary tissue graft construct. The perforated tissue graft compositions have enhanced mechanical and remodeling properties relative to non-perforated submucosal tissue grafts.
    Type: Grant
    Filed: September 18, 1997
    Date of Patent: December 7, 1999
    Assignees: Purdue Research Foundation, Methodist Hospital of Indiana, Inc.
    Inventors: Bryan Whitson, Boyle Cheng, Stephen F. Badylak
  • Method of repairing perforated submucosal tissue graft constructs
    Patent number: 5968096
    Abstract: A perforated unitary multi-laminar tissue graft construct and method for preparing such construct is described. The method comprises overlapping strips of submucosa tissue with other strips of submucosal tissue, compressing at least the overlapped portions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets, and perforating the resulting unitary tissue graft construct. The perforated tissue graft compositions have enhanced mechanical and remodeling properties relative to non-perforated submucosal tissue grafts.
    Type: Grant
    Filed: August 6, 1997
    Date of Patent: October 19, 1999
    Assignees: Purdue Research Foundation, Clarian Health Partners
    Inventors: Bryan Whitson, Boyle Cheng, Stephen F. Badylak
  • Large area submucosal tissue graft constructs and method for making the same
    Patent number: 5885619
    Abstract: A unitary heterolaminar tissue graft construct is prepared by fusing partially overlapped strips or sheets of submucosa tissue. The submucosa components are fused by compressing at least the overlapped positions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets. Three dimensional graft constructs can be prepared by using complementary non-planar compressive surfaces.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: March 23, 1999
    Assignees: Purdue Research Foundation, Methodist Hospital of Indiana, Inc.
    Inventors: Umesh H. Patel, Michael C. Hiles, Bryan Whitson, Boyle Cheng, Stephen F. Badylak, Klod Kokini
  • Perforated submucosal tissue graft constructs
    Patent number: 5755791
    Abstract: A perforated unitary multi-laminar tissue graft construct and method for preparing such construct is described. The method comprises overlapping strips of submucosa tissue with other strips of submucosal tissue, compressing at least the overlapped portions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets, and perforating the resulting unitary tissue graft construct. The perforated tissue graft compositions have enhanced mechanical and remodeling properties relative to non-perforated submucosal tissue grafts.
    Type: Grant
    Filed: April 5, 1996
    Date of Patent: May 26, 1998
    Assignees: Purdue Research Foundation, Methodist Hospital of Indiana
    Inventors: Bryan Whitson, Boyle Cheng, Stephen F. Badylak
  • Large area submucosal tissue graft constructs
    Patent number: 5711969
    Abstract: A unitary heterolaminar tissue graft construct is prepared by fusing partially overlapped strips or sheets of submucosa tissue. The submucosa components are fused by compressing at least the overlapped positions of said strips between two surfaces under conditions that allow or promote dehydration of the compressed submucosa sheets. Three dimensional graft constructs can be prepared by using complementary non-planar compressive surfaces.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: January 27, 1998
    Assignees: Purdue Research Foundation, Methodist Hospital of Indiana
    Inventors: Umesh H. Patel, Michael C. Hiles, Bryan Whitson, Boyle Cheng, Stephen F. Badylak, Klod Kokini