Patents by Inventor Bryant J. Pudil
Bryant J. Pudil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140216250Abstract: A degassing module for removal of air and other gases during operation of a medical therapy device that delivers any one of hemodialysis, hemodiafiltration and hemofiltration. The degassing module has a flow-through first chamber that has a hydrophobic vent membrane that has an exterior and interior side forming a portion of the flow-through chamber. The hydrophobic vent membrane is positioned at a higher elevation on the flow-through chamber than a fluid outlet. Fluid flows through the flow-through chamber in a downward direction relative to the hydrophobic vent membrane. A flow-through chamber has a cross sectional area configured to provide for a downward flow velocity of the fluid to be less than the upward rise velocity of a smallest bubble to be removed from the fluid.Type: ApplicationFiled: February 1, 2013Publication date: August 7, 2014Applicant: MEDTRONIC, INC.Inventors: Thomas E. Meyer, David B. Lura, Bryant J. Pudil, Martin T. Gerber
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Publication number: 20140190885Abstract: A system for measuring at least one fluid characteristic at various stages within a sorbent system that has a sorbent cartridge that has at least one material layer and at least one fluid passageway in at least one location in the sorbent system to provide a diverted sample stream from the various stages. At least one fluid characteristic of the diverted sample stream is measured.Type: ApplicationFiled: March 15, 2013Publication date: July 10, 2014Applicant: MEDTRONIC, INC.Inventors: Thomas E. Meyer, David B. Lura, Bryant J. Pudil, Martin T. Gerber
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Publication number: 20140190886Abstract: A blood based solute monitoring system for measuring at least one blood solute species that has a first recirculation flow path in fluid communication with a dialyzer. The first recirculation flow path is configured to allow a fluid to recirculate through a dialyzer such that the concentration of at least one solute species in the fluid becomes equilibrated to the solute species concentration of the blood in a blood compartment of the dialyzer. The blood solute monitoring system has at least one sensor to measure a fluid characteristic.Type: ApplicationFiled: March 15, 2013Publication date: July 10, 2014Applicant: MEDTRONIC, INC.Inventors: Bryant J. Pudil, Thomas E. Meyer, David B. Lura, Martin T. Gerber
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Publication number: 20140190891Abstract: A sorbent cartridge that has at least one sensor located within the sorbent cartridge.Type: ApplicationFiled: March 15, 2013Publication date: July 10, 2014Applicant: Medtronic, Inc.Inventors: David B. Lura, Thomas E. Meyer, Bryant J. Pudil, Martin T. Gerber, Kenneth J. Collier
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Publication number: 20140190876Abstract: A sorbent based monitoring system for measuring the solute concentration of at least one component of a fluid. The system has a sorbent regeneration system for regeneration of the fluid and has a sorbent cartridge that has at least one material layer. The fluid is conveyed through the sorbent cartridge and contacts at least one sensor after having contacted at least one material layer.Type: ApplicationFiled: March 8, 2013Publication date: July 10, 2014Applicant: MEDTRONIC, INC.Inventors: Thomas E. Meyer, David B. Lura, Bryant J. Pudil, Martin T. Gerber
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Publication number: 20140158623Abstract: Systems and methods for managing the sodium concentration of a dialysate fluid during hemodialysis therapy and adjusting sodium concentration using a sodium management system to generate a sodium-modified fluid. The systems and methods also provide a mechanism for controlled addition of sodium ions to the dialysate to generate a predetermined total sodium concentration in a dialysate.Type: ApplicationFiled: February 2, 2013Publication date: June 12, 2014Applicant: Medtronic, Inc.Inventors: Bryant J. PUDIL, Martin T. Gerber, David B. Lura, Thomas E. Meyer
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Publication number: 20140158588Abstract: Systems and methods for managing the pH of a dialysate fluid during hemodialysis therapy. The systems and methods adjust dialysate pH and buffer concentration to generate a predetermined total bicarbonate buffer concentration in a dialysate entering a dialyzer.Type: ApplicationFiled: February 2, 2013Publication date: June 12, 2014Applicant: Medtronic, Inc.Inventors: Bryant J. PUDIL, Martin T. Gerber, David B. Lura, Thomas E. Meyer
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Publication number: 20140158538Abstract: Systems and methods for managing the potassium concentration of a dialysate fluid during hemodialysis therapy using cation exchange materials that do not release sodium ions.Type: ApplicationFiled: February 2, 2013Publication date: June 12, 2014Applicant: Medtronic, Inc.Inventors: Kenneth J. COLLIER, Martin T. Gerber, David B. Lura, Thomas E. Meyer, Bryant J. Pudil
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Publication number: 20130274642Abstract: A dialysis device for operation in multiple modes and for maintaining a known gradient of potassium ion or other electrolyte between the blood of a patient and a dialysate fluid is described. The dialysis device is capable of being used for hemodialysis or peritoneal dialysis, and the dialysis device is capable of operation with a dialysate purification unit outside of a clinical setting or with a supply of water that can be supplied in a clinical setting. The dialysis device has a composition sensor containing a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of the patient's blood and the dialysate fluid and an infusate pump operated to adjust a potassium ion concentration in the dialysate fluid based at least in part on data from the composition sensor.Type: ApplicationFiled: March 15, 2013Publication date: October 17, 2013Inventors: Orhan Soykan, Bryant J. Pudil, Thomas E. Meyer, Linda L. Ruetz, Carl Schu
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Publication number: 20130213890Abstract: Apparatuses, systems, and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge, and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. A first sorbent cartridge is provided for use in a portable treatment module having activated carbon and zirconium oxide. The system also provides for the monitoring of an inlet and outlet conductivity of a sorbent cartridge containing urease to provide a facility to quantify or monitor the removal of urea by a detachable urea removal module.Type: ApplicationFiled: August 15, 2012Publication date: August 22, 2013Applicant: Medtronic, Inc.Inventors: Thomas D. Kelly, SuPing Lyu, Bryant J. Pudil, Thomas E. Meyer
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Publication number: 20130199998Abstract: Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.Type: ApplicationFiled: August 2, 2012Publication date: August 8, 2013Applicant: MEDTRONIC, INC.Inventors: Thomas D. Kelly, SuPing Lyu, Bryant J. Pudil, Thomas E. Meyer
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Patent number: 8475823Abstract: Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of baclofen formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least thirty days, at least sixty days, at least one hundred days or at least one hundred and thirty-five days.Type: GrantFiled: April 17, 2009Date of Patent: July 2, 2013Assignee: Medtronic, Inc.Inventors: Christopher M. Hobot, Michael E. Benz, Keith R. Hildebrand, Bryant J. Pudil
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Publication number: 20120289881Abstract: An implantable dialysis device with a related medical system for intracorporeal dialysis and ultrafiltration of blood, and methods of use are described. The medical system includes an extracorporeal module, a cutaneous module, and an implantable module. Features of the implantable module facilitate delivery and flow of blood and dialysate through the medical system. A filter pack within the implantable module performs dialysis and ultrafiltration of blood. System cleansing is also described.Type: ApplicationFiled: May 2, 2012Publication date: November 15, 2012Applicant: Medtronic, Inc.Inventors: SuPing Lyu, Thomas Edward Meyer, Mark Fredrick Daniels, Bryant J. Pudil
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Publication number: 20120273354Abstract: A dialysis device for operation in multiple modes and for maintaining a known gradient of potassium ion or other electrolyte between the blood of a patient and a dialysate fluid is described. The dialysis device is capable of being used for hemodialysis or peritoneal dialysis, and the dialysis device is capable of operation with a dialysate purification unit outside of a clinical setting or with a supply of water that can be supplied in a clinical setting. The dialysis device has a composition sensor containing a potassium-sensitive electrode for measuring a potassium ion concentration in one or more of the patient's blood and the dialysate fluid and an infusate pump operated to adjust a potassium ion concentration in the dialysate fluid based at least in part on data from the composition sensor.Type: ApplicationFiled: April 19, 2012Publication date: November 1, 2012Applicant: MEDTRONIC, INC.Inventors: Soykan Orhan, Bryant J. Pudil, Thomas E. Meyer
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Patent number: 8232322Abstract: Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from the controlled release of an agent(s) over a period of time. The polymers are prepared by a process involving various alternative and sequential steps that allow the design a priori of products with specific characteristics. The polymers are suitable as delivery systems, either by themselves, as compositions, formulations or devices.Type: GrantFiled: July 9, 2009Date of Patent: July 31, 2012Assignee: Rutgers, The State University of New JerseyInventors: Anthony East, Alan Letton, Suseela Kanamathareddy, Bryant J. Pudil, Stephen Goodrich, Michael B. Hicks, Yun Choe
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Publication number: 20100152410Abstract: Anhydride polymers that release active or activatable agent(s) have pre-selected properties such as molecular weight, flexibility, hardness, adhesiveness, and other valuable properties. The polymers are suitable for use in compositions, formulations, coatings, devices, and the like that benefit from the controlled release of an agent(s) over a period of time. The polymers are prepared by a process involving various alternative and sequential steps that allow the design a priori of products with specific characteristics. The polymers are suitable as delivery systems, either by themselves, as compositions, formulations or devices.Type: ApplicationFiled: July 9, 2009Publication date: June 17, 2010Applicant: Rutgers, The State University of New JerseyInventors: Anthony East, Alan Letton, Suseela Kanamathareddy, Bryant J. Pudil, Stephen Goodrich, Michael B. Hicks, Yun Choe
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Publication number: 20090208554Abstract: Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of baclofen formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least thirty days, at least sixty days, at least one hundred days or at least one hundred and thirty-five days.Type: ApplicationFiled: April 17, 2009Publication date: August 20, 2009Applicant: Medtronic, Inc.Inventors: Christopher M. Hobot, Michael E. Benz, Keith R. Hildebrand, Bryant J. Pudil
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Publication number: 20090202436Abstract: Effective treatments of pain, such as chronic pelvic pain, for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of bupivacaine formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least thirty days, at least sixty days, at least one hundred days or at least one hundred and thirty-five days.Type: ApplicationFiled: April 17, 2009Publication date: August 13, 2009Applicant: Medtronic, Inc.Inventors: Christopher M. Hobot, Michael E. Benz, Keith R. Hildebrand, Bryant J. Pudil
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Publication number: 20090202604Abstract: Effective treatments of pain for extended periods of time are provided. The treatments include the administration of one or more drug depots intraspinally wherein the drug depots include an effective amount of a benzodiazepine, such as midazolam, formulated within a polyorthoester. By administration of one or more drug depots, one can relieve pain caused by diverse sources, including but not limited to chronic pelvic pain syndromes, spinal disc herniation (i.e. sciatica), spondilothesis, stenosis, discongenic back pain and joint pain, as well as pain that is incidental to surgery. In some embodiments, the relief can be for at least twenty-five days, at least fifty days, at least one hundred days or at least one hundred and thirty-five days.Type: ApplicationFiled: April 17, 2009Publication date: August 13, 2009Applicant: Medtronic, Inc.Inventors: Christopher M. Hobot, Michael E. Benz, Keith R. Hildebrand, Bryant J. Pudil
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Patent number: D705432Type: GrantFiled: February 21, 2013Date of Patent: May 20, 2014Assignee: Medtronic, Inc.Inventors: David B. Lura, Martin T Gerber, Bryant J. Pudil, Thomas E. Meyer, Brian Mullins