Patents by Inventor Bryce Alden Harrison

Bryce Alden Harrison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted pyrrolo[2,3-d]pyrimidines as LIM kinase 2 inhibitors
    Patent number: 8507672
    Abstract: Substituted pyrrolo[2,3-d]pyrimidine-based compounds useful as inhibitors of LIM kinase 2 are disclosed. Also disclosed are pharmaceutical compositions comprising the compounds and methods of their use to treat, manage and prevent inflammatory diseases and disorders, cancer, and diseases and disorders of the eye.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: August 13, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins, Dennis S. Rice, Michael Victor Voronkov, Yulian Zhang
  • Sulfanyl-tetrahydropyran-based compounds and methods of their use
    Patent number: 8476413
    Abstract: Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: July 2, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins
  • LIMK2 inhibitors, compositions comprising them, and methods of their use
    Patent number: 8450332
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: May 28, 2013
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hugh Alfred Burgoon, Nicole Cathleen Goodwin, Bryce Alden Harrison, Jason Patrick Healy, Ying Liu, Ross Mabon, Brett Marinelli, David Brent Rawlins, Dennis Stewart Rice, Norris Andrew Whitlock
  • LIMK2 INHIBITORS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
    Publication number: 20120329818
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 27, 2012
    Inventors: Hugh Alfred BURGOON, Nicole Cathleen GOODWIN, Bryce Alden HARRISON, Jason Patrick HEALY, Ying LIU, Ross MABON, Brett MARINELLI, David Brent RAWLINS, Dennis Stewart RICE, Norris Andrew WHITLOCK
  • Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors
    Patent number: 8293878
    Abstract: Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed. Particular inhibitors are compounds of formula I.
    Type: Grant
    Filed: August 11, 2011
    Date of Patent: October 23, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Nicole Cathleen Goodwin, Bryce Alden Harrison, Shinya Iimura, Ross Mabon, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang, Matthew Mangzhu Zhao
  • LIMK2 inhibitors, compositions comprising them, and methods of their use
    Patent number: 8193202
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: June 5, 2012
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Hugh Alfred Burgoon, Nicole Cathleen Goodwin, Bryce Alden Harrison, Jason Patrick Healy, Ying Liu, Ross Mabon, Brett Marinelli, David Brent Rawlins, Dennis Stewart Rice, Norris Andrew Whitlock
  • METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS
    Publication number: 20120095197
    Abstract: Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed.
    Type: Application
    Filed: August 11, 2011
    Publication date: April 19, 2012
    Inventors: Nicole Cathleen Goodwin, Bryce Alden Harrison, Shinya Iimura, Ross Mabon, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang, Matthew Mangzhu Zhao
  • Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitors
    Patent number: 8026347
    Abstract: Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed.
    Type: Grant
    Filed: July 17, 2008
    Date of Patent: September 27, 2011
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Nicole Cathleen Goodwin, Bryce Alden Harrison, Shinya Iimura, Ross Mabon, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang, Matthew Mangzhu Zhao
  • SULFANYL-TETRAHYDROPYRAN-BASED COMPOUNDS AND METHODS OF THEIR USE
    Publication number: 20100311673
    Abstract: Sulfanyl-tetrahydropyran-based compounds, pharmaceutical compositions comprising them, and methods of their use for the treatment of diseases and disorders such as diabetes and obesity are disclosed.
    Type: Application
    Filed: August 18, 2010
    Publication date: December 9, 2010
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins
  • Piperdine-based inhibitors of sodium glucose co-transporter 2 and methods of their use
    Patent number: 7846945
    Abstract: Compounds and pharmaceutical compositions comprising them are disclosed that may be useful for the treatment of diseases and disorders such as diabetes and obesity.
    Type: Grant
    Filed: March 4, 2008
    Date of Patent: December 7, 2010
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins
  • Inhibitors of sodium glucose co-transporter 2 and methods of their use
    Patent number: 7781577
    Abstract: Compounds and pharmaceutical compositions comprising them are disclosed that may be useful for the treatment of diseases and disorders such as diabetes and obesity.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: August 24, 2010
    Assignee: Lexicon Pharmaceuticals, Inc.
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins, Nicole C Goodwin
  • LIMK2 INHIBITORS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
    Publication number: 20090264450
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Application
    Filed: April 20, 2009
    Publication date: October 22, 2009
    Inventors: Hugh Alfred Burgoon, Nicole Cathleen Goodwin, Bryce Alden Harrison, Jason Patrick Healy, Ying Liu, Ross Mabon, Brett Marinelli, David Brent Rawlins, Dennis Stewart Rice, Norris Andrew Whitlock
  • KINASE INHIBITORS, COMPOSITIONS COMPRISING THEM, AND METHODS OF THEIR USE
    Publication number: 20090042893
    Abstract: Inhibitors of LIM kinase 2 are disclosed, along with pharmaceutical compositions comprising them and methods of their use.
    Type: Application
    Filed: August 8, 2008
    Publication date: February 12, 2009
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins, Dennis S. Rice, Michael Victor Voronkov, Yulian Zhang
  • METHODS AND COMPOUNDS USEFUL FOR THE PREPARATION OF SODIUM GLUCOSE CO-TRANSPORTER 2 INHIBITORS
    Publication number: 20090030198
    Abstract: Methods of synthesizing sodium glucose co-transporter 2 inhibitors, as well as compounds useful therein, are disclosed.
    Type: Application
    Filed: July 17, 2008
    Publication date: January 29, 2009
    Inventors: Nicole Cathleen Goodwin, Bryce Alden Harrison, Shinya Iimura, Ross Mabon, Qiuling Song, Wenxue Wu, Jie Yan, Haiming Zhang, Matthew Mangzhu Zhao
  • Inhibitors of Sodium Glucose Co-Transporter 2 and Methods of Their Use
    Publication number: 20080221164
    Abstract: Compounds and pharmaceutical compositions comprising them are disclosed that may be useful for the treatment of diseases and disorders such as diabetes and obesity.
    Type: Application
    Filed: March 4, 2008
    Publication date: September 11, 2008
    Inventors: Nicole C. Goodwin, Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins
  • INHIBITORS OF SODIUM GLUCOSE CO-TRANSPORTER 2 AND METHODS OF THEIR USE
    Publication number: 20080113922
    Abstract: Compounds and pharmaceutical compositions comprising them are disclosed that may be useful for the treatment of diseases and disorders such as diabetes and obesity.
    Type: Application
    Filed: September 27, 2007
    Publication date: May 15, 2008
    Inventors: Bryce Alden Harrison, Spencer David Kimball, Ross Mabon, David Brent Rawlins