Patents by Inventor Bryce V. Plapp

Bryce V. Plapp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Autoinducer synthase modulating compounds and uses therefore
    Publication number: 20040152660
    Abstract: Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifying modulators of the autoinducer synthesis reaction is also provided. Such modulators are useful for controlling bacterial growth and can be used for therapeutic treatment of bacterial infections particularly in immunocompromised subjects. They are also useful in treating disease states associated with autoinducer synthesis and biofilm development.
    Type: Application
    Filed: March 5, 2004
    Publication date: August 5, 2004
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: John E. Cronan, Bryce V. Plapp, E. Peter Greenberg, Matthew R. Parsek
  • Autoinducer synthase modulating compounds and uses thereof
    Patent number: 6723321
    Abstract: Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifing modulators of the autoinducer synthesis reaction is also provided. Such modulators are useful for controlling bacterial growth and can be used for therapeutic treatment of bacterial infections particularly in immunocompromised subjects. They are also useful in treating disease states associated with autoinducer synthesis and biofilm development.
    Type: Grant
    Filed: January 6, 1999
    Date of Patent: April 20, 2004
    Assignees: The Board of Trustees of the University of Illinois, The University of Iowa Research Foundation
    Inventors: E. Peter Greenberg, John E. Cronan, Jr., Bryce V. Plapp, Matthew R. Parsek
  • AUTOINDUCER SYNTHASE MODULATING COMPOUNDS AND USES THEREFORE
    Publication number: 20030054512
    Abstract: Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifing modulators of the autoinducer synthesis reaction is also provided. Such modulators are useful for controlling bacterial growth and can be used for therapeutic treatment of bacterial infections particularly in immunocompromised subjects. They are also useful in treating disease states associated with autoinducer synthesis and biofilm development.
    Type: Application
    Filed: January 6, 1999
    Publication date: March 20, 2003
    Applicant: LAHIVE AND COCKFIELD
    Inventors: JOHN E. CRONAN, BRYCE V. PLAPP, E. PETER GREENBERG, MATTHEW R. PARSEK
  • Inhibition of alcohol metabolism by tetramethylene sulfoxides
    Patent number: 4482568
    Abstract: Tetramethylene sulfoxide and its substituted derivatives have been found to be exceptionally potent inhibitors of oxidation of alcohols by liver alcohol dehydrogenases.
    Type: Grant
    Filed: October 17, 1983
    Date of Patent: November 13, 1984
    Assignee: University of Iowa Research Foundation
    Inventors: Bryce V. Plapp, Vijay K. Chadha