Patents by Inventor Bryon S. Severns

Bryon S. Severns has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-aminoimidazo[1,2-b]pyridazine analogs as rho kinase inhibitors for the treatment of rho kinase-mediated diseases and conditions
    Patent number: 7820670
    Abstract: Methods for using 6-aminoimidazo[1,2-b]pyridazine analogs are disclosed herein to treat rho kinase-mediated diseases or rho kinase-mediated conditions, including controlling intraocular pressure and treating glaucoma, are disclosed. Ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma, and additionally useful for controlling intraocular pressure, the compositions comprising an effective amount of 6-aminoimidazo[1,2-b]pyridazine analogs, are disclosed herein.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: October 26, 2010
    Assignee: Alcon Research, Ltd.
    Inventors: Hwang-Hsing Chen, Andrew Rusinko, Mark R. Hellberg, Bryon S. Severns, Alan J. Henderson, Cheng Guo, Mark Hadden
  • METHOD OF TREATING ASTHMA, ALLERGIC RHINITIS, AND SKIN DISORDERS
    Publication number: 20090156667
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs is disclosed for the treatment of asthma, allergic rhinitis, and skin disorders such as allergic dermatitis, contact hypersensitivity, urticaria (hives), rosacea, or psoriasis.
    Type: Application
    Filed: February 19, 2009
    Publication date: June 18, 2009
    Applicant: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard, Bryon S. Severns
  • 6-AMINOIMIDAZO[1,2-b]PYRIDAZINE ANALOGS AS RHO KINASE INHIBITORS FOR THE TREATMENT OF RHO KINASE-MEDIATED DISEASES AND CONDITIONS
    Publication number: 20080153813
    Abstract: Methods for using 6-aminoimidazo[1,2-b]pyridazine analogs are disclosed herein to treat rho kinase-mediated diseases or rho kinase-mediated conditions, including controlling intraocular pressure and treating glaucoma, are disclosed. Ophthalmic pharmaceutical compositions useful in the treatment of eye diseases such as glaucoma, and additionally useful for controlling intraocular pressure, the compositions comprising an effective amount of 6-aminoimidazo[1,2-b]pyridazine analogs, are disclosed herein.
    Type: Application
    Filed: December 19, 2007
    Publication date: June 26, 2008
    Applicant: ALCON MANUFACTURING, LTD.
    Inventors: Hwang-Hsing CHEN, Andrew RUSINKO, Mark R. HELLBERG, Bryon S. SEVERNS, Alan J. HENDERSON, Cheng GUO, Mark HADDEN
  • Pyranoindazoles and their use for the treatment of glaucoma
    Patent number: 6881749
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: April 19, 2005
    Assignee: Alcon, Inc.
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns
  • Pyranoindazoles and their use for the treatment of glaucoma
    Publication number: 20040106609
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: November 24, 2003
    Publication date: June 3, 2004
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns
  • Pyranoindazoles and their use for the treatment of glaucoma
    Patent number: 6696476
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: December 11, 2002
    Date of Patent: February 24, 2004
    Assignee: Alcon, Inc.
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns
  • Pyranoindazoles and their use for the treatment of glaucoma
    Publication number: 20030171418
    Abstract: Pyranoindazoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: December 11, 2002
    Publication date: September 11, 2003
    Inventors: Hwang-Hsing Chen, Jesse A. May, Bryon S. Severns