Abstract: A method for treating Peyronie's disease includes providing an elongated tube having an inner diameter that is substantially equal to the outer diameter of an erect penis, such that the walls thereof will be adjacent the outer surface of the erect penis. A base portion is provided on the end of the elongated tube that is operable to be disposed about the base portion of an adult male penis to provide a seal therewith to air flow. The adult male penis is inserted into the end of the tube having the base portion associated therewith and the base portion moved downward against the base of the penis. A high air flow vacuum source is disposed and connected to the opposite end of the tube, such that a negative pressure is formed therein. The negative pressure results in the penis moving from a flaccid condition to an erect condition.