Abstract: A monoclonal antibody or an antigen-binding fragment thereof according to an embodiment of the present invention can bind to lymphocyte-activation gene 3 (LAG-3) including a heavy chain variable region and a light chain variable region and inhibit the activity thereof. Thus it is expected to be useful for the development of immunotherapeutic agents for various disorders that are associated with LAG-3.

Abstract: Disclosed are layered ferric rust and iron hydroxide nanoparticles including the same, wherein the layered ferric rust has a novel crystal structure that satisfies conditions (a) to (c) below: (a) a crystal system belongs to a monoclinic system; (b) a space group belongs to Pn (No. 7); and (c) unit cell parameters are a = 3.854 ± 0.002 Å, b = 11.491 ± 0.007 Å, c = 9.818 ± 0.004 Å, and ? = 88.47 ± 0.005° (b is the distance between layers in the [010] axial direction).

Abstract: The present invention relates to a magnetic-optical composite nanostructure, which has a heterogeneous nature due to consisting of a first core-shell nanoparticle and second core-shell nanoparticles and thus realizes magnetic and optical functions at the same time.

Abstract: Provided are a kit for detecting Coronavirus using magnetic nanoparticles and a method detecting Coronavirus using the same. The kit for detecting Coronavirus includes a reactor having an opening on one side and provided with a sample containing Coronavirus, at least one magnetic nanoparticle part provided in the reactor, a conductive substrate provided to cover the opening of the reactor, and a magnetic field applying part for applying a magnetic field to the reactor, in which the magnetic nanoparticle part includes a magnetic nanoparticle including a core portion made of iron oxide and a shell portion made of gold and provided to surround the core portion, and a primer attached to the shell portion of the magnetic nanoparticle.

Abstract: Provided are a kit and a method for detecting target nucleic acids using magnetic nanoparticles. The kit for detecting target nucleic acids includes a reactor having an opening on one side and provided with a sample containing target nucleic acids, at least one magnetic nanoparticle part provided in the reactor, a conductive substrate provided to cover the opening of the reactor, and a magnetic field applying part for applying a magnetic field to the reactor, in which the magnetic nanoparticle part includes a magnetic nanoparticle including a core portion made of iron oxide and a shell portion made of gold and provided to surround the core portion, and a primer attached to the shell portion of the magnetic nanoparticle.

Abstract: The present disclosure relates to a composition for enhancing an immune response using the activating function of dendritic cells of a stromal vascular fraction isolated from adipose tissue, and in particular, a composition for enhancing an immune response for anti-tumor use.

Abstract: The present invention relates to a method of controlling the arrangement of building block nanocrystals in iron oxide mesocrystals by controlling the type of surface ligand, the method including mixing an iron ion precursor and a surface ligand. The present invention can provide nanoparticles having different magnetic properties by controlling the crystallographic arrangement of building block nanocrystals in mesocrystals according to surface ligands.

Abstract: The present invention relates to a fiber-nanowire composite-based sheet having super-amphiphilic characteristics. In the present invention, fibers including metal nanoparticles or metal oxide nanoparticles embedded in the fibers or located on the surface of the fibers are synthesized, and a sheet based on a composite in which metal nanowires or metal oxide nanowires have been grown from the above fibers is provided. A sheet of the present invention has super-amphiphilic characteristics and can be used in various fields such as the antibacterial filter field, the antibacterial film field, the antiviral filter field, the antiviral film field, the antifouling coating field, the drug delivery vehicle field, or the water treatment filter field.

Abstract: A multi-component mesocrystalline nanoparticle is provided. The multi-component mesocrystalline nanoparticle includes an iron oxide nanocluster; and metal oxide nanocrystals bound to a surface of the iron oxide.

Abstract: The present invention relates to a magnetic-optical composite nanostructure, which has a heterogeneous nature due to consisting of a first core-shell nanoparticle and second core-shell nanoparticles and thus realizes magnetic and optical functions at the same time.

Abstract: Provided are a nanofiber-nanowire composite and a method for producing the same. The method includes preparing a nanoparticle using a dipolar solvent, producing a nanofiber-nanoparticle composite in an electrospinning synthesis solution including the nanoparticle through electrospinning, and growing a nanowire from the nanoparticle by hydrothermally synthesizing a dried nanofiber-nanoparticle composite.

Abstract: Provided are a nanoparticle-polymer fluorescent composite and a method of preparing the same. The method includes preparing magnetite (Fe3O4) nanoparticles, mixing the magnetite (Fe3O4) nanoparticles, an organic polymer having an aliphatic carbon chain, and a solvent for dissolving the organic polymer to prepare a preliminary composite and drying the preliminary composite to form a nanoparticle polymer composite, and irradiating a pulse laser to the nanoparticle polymer composite to change the magnetite (Fe3O4) nanoparticles to Wustite nanoparticles and providing conjugated polymer characteristics to the organic polymer.

Abstract: Provided are a nanoparticle-polymer fluorescent composite and a method of preparing the same. The method includes preparing magnetite (Fe3O4)nanoparticles, mixing the magnetite (Fe3O4) nanoparticles, an organic polymer having an aliphatic carbon chain, and a solvent for dissolving the organic polymer to prepare a preliminary composite and drying the preliminary composite to form a nanoparticle polymer composite, and irradiating a pulse laser to the nanoparticle polymer composite to change the magnetite (Fe3O4) nanoparticles to Wustite nanoparticles and providing conjugated polymer characteristics to the organic polymer.

Abstract: Provided are a nanofiber-nanowire composite and a method for producing the same. The method includes preparing a nanoparticle using a dipolar solvent, producing a nanofiber-nanoparticle composite in an electrospinning synthesis solution including the nanoparticle through electrospinning, and growing a nanowire from the nanoparticle by hydrothermally synthesizing a dried nanofiber-nanoparticle composite.

Abstract: An automatic, continuous and rapid charging circuit for a plurality of rechargeable batteries and method thereof are disclosed. There is provided a power supply section; a power source switching section for selectively supplying the charging voltage to one of a plurality of batteries; a switching control section for supplying switching control signals to said power source switching section; a battery detecting section; a charge completion detecting section; a display section for displaying the charging operation of the batteries; and a microcomputer for performing the overall control of the system. According to the method of the present invention, a plurality of batteries are sequentially detected as to their placing for charging, and are successively charged, by using a power supply with a power capacity required to charge only a single battery.