Patents by Inventor Bunnai Saito

Bunnai Saito has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10519110
    Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: December 31, 2019
    Assignee: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Yasutomi Asano, Takuto Kojima, Osamu Kurasawa, Tzu-Tshin Wong, Yasuhiro Hirata, Naoki Iwamura, Bunnai Saito, Yuta Tanaka, Ryosuke Arai, Shinichi Imamura, Kazuko Yonemori, Yasufumi Miyamoto, Shuji Kitamura, Osamu Sano
  • Publication number: 20190062274
    Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
    Type: Application
    Filed: October 30, 2018
    Publication date: February 28, 2019
    Inventors: Yasutomi ASANO, Takuto KOJIMA, Osamu KURASAWA, Tzu-Tshin WONG, Yasuhiro HIRATA, Naoki IWAMURA, Bunnai SAITO, Yuta TANAKA, Ryosuke ARAI, Shinichi IMAMURA, Kazuko YONEMORI, Yasufumi MIYAMOTO, Shuji KITAMURA, Osamu SANO
  • Patent number: 10189785
    Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: January 29, 2019
    Assignee: Takeda Pharmaceuticals Company Limited
    Inventors: Yasutomi Asano, Takuto Kojima, Osamu Kurasawa, Tzu-Tshin Wong, Yasuhiro Hirata, Naoki Iwamura, Bunnai Saito, Yuta Tanaka, Ryosuke Arai, Shinichi Imamura, Kazuko Yonemori, Yasufumi Miyamoto, Shuji Kitamura, Osamu Sano
  • Publication number: 20180170874
    Abstract: The present invention relates to a compound which can be useful for the treatment or prevention of SPT-related diseases including cancer and congenital diseases associated with sphingolipid accumulation (including Niemann-Pick disease).
    Type: Application
    Filed: April 19, 2016
    Publication date: June 21, 2018
    Inventors: Yasutomi ASANO, Takuto KOJIMA, Osamu KURASAWA, Tzu-Tshin WONG, Yasuhiro HIRATA, Naoki IWAMURA, Bunnai SAITO, Yuta TANAKA, Ryosuke ARAI, Shinichi IMAMURA, Kazuko YONEMORI, Yasufumi MIYAMOTO, Shuji KITAMURA, Osamu SANO
  • Publication number: 20170016139
    Abstract: The present invention provides a method for producing a single crystal of a polymer-metal complex comprising: (a) a step of dissolving in an organic solvent a tridentate ligand represented by formula (1): (wherein, Ar represents an optionally substituted trivalent aromatic group, X1 to X3 each independently represent a divalent organic group, or a single bond that directly bonds Ar and Y1, Y2, or Y3, and Y1 to Y3 each independently represent a monovalent organic group having a coordinating moiety); and (b) a step of obtaining the single crystal of the polymer-metal complex by adding to the solution obtained in step (a) a compound for providing the metal ion and an additive for changing solution properties to basic.
    Type: Application
    Filed: August 31, 2016
    Publication date: January 19, 2017
    Inventor: Bunnai SAITO
  • Publication number: 20090099381
    Abstract: The present invention relates to a production method capable of producing an optically active ?-hydroxyphosphonic acid and its derivatives with sufficiently high enantioselectivity not only for aromatic aldehydes but also for aliphatic aldehydes, and more specifically to a method of producing an optically active ?-hydroxyphosphonic acid and its derivatives, characterized in that an optically active aluminum(salalen) complex represented by any one of the following formulae (I), (I?), (II) and (II?): [wherein R1s are each alkyl group or aryl group independently; R2s are each alkyl group or aryl group independently; R3s are each alkyl group or aryl group independently, and two R3s may bond with each other to form a ring; R4s are each hydrogen atom, halogen atom, alkyl group, alkoxy group, nitro group, or cyano group independently; R5 is alkyl group; and X1 is halogen atom, alkyl group, alkoxy group, acetoxy group or toluenesulfonyloxy group] is used as a catalyst to asymmetrically hydrophosphonylate an aldeh
    Type: Application
    Filed: March 20, 2006
    Publication date: April 16, 2009
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Tsutomu Katsuki, Bunnai Saito