Abstract: There are provided a gas supply apparatus and a gas supply method that are capable of supplying hydrogen gas of a highly accurate and stable hydrogen gas concentration to a body. A ventilator 100 that supplies oxygen-containing gas and hydrogen gas includes a hydrogen gas delivery unit 8 that delivers the hydrogen gas taken in to outside of the ventilator 100, and a control unit 22 that adjusts an amount of the hydrogen gas taken into the hydrogen gas delivery unit 8. The control unit 22 adjusts the amount of the hydrogen gas taken into the hydrogen gas delivery unit 8 based on a flow rate of the oxygen-containing gas.

Abstract: Provided is a composition for improving symptoms of organ-specific autoimmune diseases. A composition comprising a hydrogen gas-containing gas as an active ingredient, for use in improving symptoms caused by an organ-specific autoimmune disease and/or reducing worsening of the symptoms in patients with an organ-specific autoimmune disease, and a method for improving symptoms including a decrease in activity levels involved in symptoms of an organ-specific autoimmune disease and/or reducing worsening of the symptoms by administering the composition to patients with the organ-specific autoimmune disease.

Abstract: Provided is a novel composition that has no side effects and can be easily produced, for use in improving symptoms of sequelae of viral infection. A composition comprising a hydrogen gas-containing gas as an active ingredient, for use in improving symptoms of sequelae of viral infection, such as pulmonary fibrosis, feeling of fatigue, malaise, shortness of breath, difficulty breathing, and/or decrease in activity levels associated with these symptoms, in a patient with sequelae of viral infection, and/or a method for improving symptoms, such as decrease in activity levels associated with these symptoms.

Abstract: Provided is a composition for treating and/or preventing cognitive impairment or dementia. The composition for treating and/or preventing cognitive impairment or dementia containing hydrogen gas, wherein the composition is used to allow the hydrogen gas to be inhaled by a subject. The concentration of the hydrogen gas to be inhaled is, for example, 0.5 to 18.3 vol %. The concentration of the hydrogen gas to be inhaled is, for example, 1 to 10 vol %. For example, the time of inhalation of the hydrogen gas is at least 10 minutes or longer per inhalation, and the frequency of inhalation of the hydrogen gas is once or more per day.

Abstract: Described is a composition for ameliorating symptoms of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and/or fibromyalgia (FM) that has few side effects and can be easily produced. Specifically, described is a composition for ameliorating at least one symptom of fatigue, headache, body pain, impaired thinking, impaired concentration, and/or impaired activity level associated with these symptoms caused by ME/CFS and/or FM in a patient, including a hydrogen gas-containing gas as an active ingredient. Also, described herein is a method for ameliorating symptoms such as fatigue, headache, body pain, impaired thinking, impaired concentration, and/or impaired activity levels associated with these symptoms caused by ME/CFS and/or FM in a patient with ME/CFS and/or FM, including administering the composition to the patient.

Abstract: An object of the present invention is to provide means for treating post-traumatic stress disorder or a blast-induced traumatic brain injury-protective agent. The present invention provides a pharmaceutical composition containing hydrogen as an active ingredient, used for treating post-traumatic stress disorder or protecting against blast-induced traumatic brain injury.

Abstract: The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.

Abstract: The present invention provides a composition for preventing or improving human osteoporosis, comprising molecular hydrogen as an active ingredient. More specifically, the present invention provides a composition for preventing or improving human osteoporosis, wherein the human osteoporosis is primary osteoporosis and/or secondary osteoporosis.

Abstract: The present invention provides a composition for maintaining a lung function in a human lung cancer and/or improving a reduction in lung function attributed to the human lung cancer. More specifically, the present invention provides a composition for maintaining a lung function in a human lung cancer and/or improving a reduction in lung function attributed to the human lung cancer in a subject, comprising molecular hydrogen as an active ingredient.

Abstract: The present invention provides a composition for prevention and/or improvement of an adverse drug reaction, a symptom associated with an adverse drug reaction, and/or an adverse reaction associated with medical treatment. More specifically, the present invention provides a composition for prevention and/or improvement of an adverse drug reaction, a symptom associated with an adverse drug reaction, and/or an adverse reaction associated with medical treatment in a subject, comprising molecular hydrogen as an active ingredient.

Abstract: The present invention provides a composition for prevention and/or improvement of encephalitis and/or meningitis. More specifically, the present invention provides a composition for prevention and/or improvement of encephalitis and/or meningitis and a symptom associated with the encephalitis and/or meningitis in a subject, comprising molecular hydrogen as an active ingredient.

Abstract: The present invention provides a composition for prevention and/or improvement of a genetic disorder. More specifically, the present invention provides a composition for prevention and/or improvement of a genetic disorder and a symptom associated with the genetic disorder in a subject, comprising molecular hydrogen as an active ingredient.

Abstract: The present invention provides a composition for regulating intracellular signal transduction. More specifically, the present invention provides a composition for prevention and/or improvement of a symptom associated with intracellular signal transduction in a subject, comprising molecular hydrogen as an active ingredient.

Abstract: The present invention provides a composition for prevention and/or improvement of pneumonia. More specifically, the present invention provides a composition for prevention and/or improvement of pneumonia and a symptom associated with pneumonia in a subject, comprising molecular hydrogen as an active ingredient.

Abstract: An object of the present invention is to provide means for treating post-traumatic stress disorder or a blast-induced traumatic brain injury-protective agent. The present invention provides a pharmaceutical composition containing hydrogen as an active ingredient, used for treating post-traumatic stress disorder or protecting against blast-induced traumatic brain injury.

Abstract: The present application provides a radiation damage protecting agent comprising hydrogen gas as an active ingredient at a concentration of 18.5% by volume or less, for treating or alleviating, in a hyperbaric capsule under a pressure higher than standard atmospheric pressure, radiation damage in a human patient who has been exposed to radiation or who has received or receives radiotherapy, and a hyperbaric capsule for administering a hydrogen gas-containing therapeutic agent such as the radiation damage protecting agent to a patient including a human.