Abstract: The present disclosure provides methods of treating cancer using complementary transgenic oncolytic viruses and genetically engineered CAR T cells. In one embodiment, the oncolytic virus comprises nucleotide sequences encoding CD19, or CD19 and IL-12, and the genetically engineered T cells express a chimeric antigen receptor that recognizes CD19.

Abstract: The present disclosure provides a chimeric antigen receptor (CAR) molecule comprising a modified hinge domain, wherein the hinge domain comprises the amino acid sequence of SEQ ID NO:1. Cells expressing a CAR comprising the modified hinge domain disclosed herein are shown to have enhanced anti-tumor activities with reduced release of pro-inflammatory cytokines.

Abstract: Polymeric compositions having a slip agent comprising a silicone and a fatty acid amide. Such polymeric compositions can exhibit lower coefficients of friction when compared to polymeric compositions containing either silicone or fatty acid amide alone. Such polymeric compositions are suitable for use in various articles of manufacture, including, for example, wire and cable jackets.

Abstract: Polymeric compositions having a slip agent comprising a silicone and a fatty acid amide. Such polymeric compositions can exhibit lower coefficients of friction when compared to polymeric compositions containing either silicone or fatty acid amide alone. Such polymeric compositions are suitable for use in various articles of manufacture, including, for example, wire and cable jackets.

Abstract: Fiber bundles (10) comprise loose fibers (11) encased within a fiber/resin composite (12). The bundles are useful as strength members for fiber optic cables. In one embodiment the bundles are prepared by a method comprising the steps of (A) bundling fibers together such that a portion of the fibers form an interior part of the bundle and a portion of the fibers form an exterior part of the bundle, and (B) impregnating the exterior part of the bundle with a resin such that (1) the fibers that form the exterior part of the bundle and the resin form a fiber/resin composite that encases the fibers that for the interior part of the bundle, and (2) the fibers that form the interior part of the bundle are not impregnated with the resin.

Abstract: This invention relates to a fiber reinforced plastic material with improved flexibility and high tensile strength for use in optic cables. The strength member composition comprises a polypropylene based thermoplastic resin, a continuous fiber having a modulus greater than 80 PGa, and talc.

Abstract: Strength members for cable, particularly fiber optic cable, are made by a method comprising the steps of: A. Wetting a fiber, e.g., fiberglass fiber, with an aqueous polymeric dispersion to form a wetted fiber, the dispersion comprising: 1. At least one thermoplastic resin, e.g., a polyolefin; 2. At least one dispersing agent, e.g., a ethylene ethyl acrylate polymer; and 3. Water; B. Removing the water from the wetted fiber, and C. Consolidating the resin on the fiber with or without curing.

Abstract: This invention relates to a fiber reinforced plastic material with improved flexibility and high tensile strength for use in optic cables. The strength member composition comprises a polypropylene based thermoplastic resin, a continuous fiber having a modulus greater than 80 PGa, and talc.

Abstract: Fiber bundles (10) comprise loose fibers (11) encased within a fiber/resin composite (12). The bundles are useful as strength members for fiber optic cables. In one embodiment the bundles are prepared by a method comprising the steps of (A) bundling fibers together such that a portion of the fibers form an interior part of the bundle and a portion of the fibers form an exterior part of the bundle, and (B) impregnating the exterior part of the bundle with a resin such that (1) the fibers that form the exterior part of the bundle and the resin form a fiber/resin composite that encases the fibers that for the interior part of the bundle, and (2) the fibers that form the interior part of the bundle are not impregnated with the resin.

Abstract: Fiber reinforced tape comprises a longitudinal axis, at least 30 percent by weight of a fiber and at least 2 percent by weight of a thermoplastic resin, with the proviso that at least 30 percent of the fibers in the tape are at least partially oriented along the longitudinal axis of the tape. The tape is useful as a strength member for wire and cable constructions, particularly fiber optic cable constructions.

Abstract: The pultrusjon process for making the composite cere of an aluminum conductor composite core (ACCC) cable is improved by replacing the traditional wet-out step of dipping the fiber in a bath of liquid rcsm with a high-pressure spray wet-out step In a preferred process, the fiber is spread out into its constituent filaments, and the resin is sprayed onto the spread-out filaments using a high-pressuic spray nozzle.

Abstract: The present invention is a fiber-polymer composite-supported conductor with a fiber-polymer composite core and a tubular metal conductor. The tubular metal conductor is on the core. Substantially all mechanical tension resulting from the disposition of the conductor is borne by the fiber-polymer composite core.