Patents by Inventor Burcin ALTUN

Burcin ALTUN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proximity-based sortase-mediated protein purification and ligation
    Patent number: 12187809
    Abstract: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
    Type: Grant
    Filed: January 28, 2022
    Date of Patent: January 7, 2025
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: Andrew Tsourkas, Burcin Altun, Hejia Henry Wang, Feifan Yu
  • BISPECIFIC CYTOTOXIC LYMPHOCYTE OR MACROPHAGE-REDIRECTING AUTOANTIBODIES, METHODS FOR PRODUCTION THEREOF AND METHODS OF TREATMENT
    Publication number: 20240271091
    Abstract: A bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for producing bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for treating a subject in need thereof comprising administering to the subject an isolated bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody.
    Type: Application
    Filed: January 24, 2024
    Publication date: August 15, 2024
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Andrew TSOURKAS, James Z. HUI, Burcin ALTUN, Fabiana ZAPPALA
  • Bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibodies, methods for production thereof and methods of treatment
    Patent number: 11913026
    Abstract: A bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for producing bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for treating a subject in need thereof comprising administering to the subject an isolated bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: February 27, 2024
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Andrew Tsourkas, James Z. Hui, Burcin Altun, Fabiana Zappala
  • PROXIMITY-BASED SORTASE-MEDIATED PROTEIN PURIFICATION AND LIGATION
    Publication number: 20220235145
    Abstract: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
    Type: Application
    Filed: January 28, 2022
    Publication date: July 28, 2022
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Andrew TSOURKAS, Burcin ALTUN, Hejia Henry WANG, Feifan YU
  • Proximity-based sortase-mediated protein purification and ligation
    Patent number: 11236177
    Abstract: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: February 1, 2022
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Andrew Tsourkas, Burcin Altun, Hejia Henry Wang, Feifan Yu
  • BISPECIFIC CYTOTOXIC LYMPHOCYTE OR MACROPHAGE-REDIRECTING AUTOANTIBODIES, METHODS FOR PRODUCTION THEREOF AND METHODS OF TREATMENT
    Publication number: 20200299646
    Abstract: A bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for producing bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for treating a subject in need thereof comprising administering to the subject an isolated bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody.
    Type: Application
    Filed: March 17, 2020
    Publication date: September 24, 2020
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Andrew TSOURKAS, James Z. HUI, Burcin ALTUN, Fabiana ZAPPALA
  • PROXIMITY-BASED SORTASE-MEDIATED PROTEIN PURIFICATION AND LIGATION
    Publication number: 20200277403
    Abstract: The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers.
    Type: Application
    Filed: September 14, 2017
    Publication date: September 3, 2020
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: Andrew TSOURKAS, Burcin ALTUN, Hejia Henry WANG, Feifan YU