Patents by Inventor Burkhard Sachse
Burkhard Sachse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Substituted pyrimidines, processes for their preparation, and their use as pesticides and fungicides
Patent number: 6596727Abstract: Substituted 4-amino- and 4-alkoxy-cycloalkylpyrimidines, processes for their preparation, and their use as pesticides and fungicides The invention relates to compounds of the formula in which R1, R2, R3 and Q are as defined in the description, X is NH or oxygen and E is a bond or a 1- to 4-membered carbon chain, to a process for their preparation, to agents containing them, and to their use in the control of pests and as fungicides.Type: GrantFiled: March 15, 1996Date of Patent: July 22, 2003Assignee: Hoechst AktiengesellschaftInventors: Wolfgang Schaper, Rainer Preuss, Gerhard Salbeck, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lümmen, Werner Bonin -
Patent number: 5925653Abstract: Substituted pyridines and pyrimidines, processes for their preparation and their use as pesticides and fungicides.The invention relates to compounds of the formula ##STR1## in which A is N or CH, R is H, halogen, alkyl or cycloalkyl, R.sup.2 and R.sup.3 are H, halogen or an aliphatic radical or together form a ring, X is O, NH or S(O).sub.q where q=0, 1 of 2, R.sup.4.sub.q is 0-4 radicals selected from the series consisting of halogen, optionally substituted alkyl or alkoxy, cycloalkyl and optionally substituted phenyl, n=0-2, m=1-3 and Y is optionally substituted methylene or imino.The invention furthermore relates to a process for their preparation and for their use as pesticides, in particular as insecticides, acaricides and fungicides. The compounds are furthermore suitable for controlling nematodes, helminths and molluscs, and for controlling endoparasites and ectoparasites in the field of veterinary medicine.Type: GrantFiled: September 6, 1996Date of Patent: July 20, 1999Assignee: Hoechst Schering AgrEvo GmbHInventors: Rainer Preuss, Wolfgang Schaper, Martin Markl, Harald Jakobi, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lummen, Werner Bonin
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Patent number: 5877322Abstract: The invention relates to compounds of the formula ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are H, halogen, an aliphatic radical or an aromatic radical, X is O, S or optionally substituted imino, Y is a bond or a bivalent optionally substituted hydrocarbon radical and Z is optionally substituted cycloalkyl or cycloalkenyl. The invention furthermore relates to processes for their preparation and their use as pesticides, in particular as insecticides, acaricides and fungicides.Type: GrantFiled: September 12, 1994Date of Patent: March 2, 1999Assignee: Hoechst Schering AgrEvo GmbHInventors: Dieter Bernd Reuschling, Adolf Heinz Linkies, Volkmar Wehner, Rainer Preuss, Wolfgang Schaper, Harald Jakobi, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lummen, Werner Bonin
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Patent number: 5859009Abstract: Substituted spiroalkylamino and -alkoxy heterocycles, processes for their preparation, and their use as pesticides and fungicidesThe invention relates to compounds of the formula ##STR1## in which Het is optionally substituted 4-pyridyl or 4-pyrimidinyl; X is NH, O or S(O).sub.0-2 ; E is a bond or alkanediyl; Y and Z are CH.sub.2, O and/or S(O).sub.0-2 ; W is (CH.sub.2).sub.0-4 ; R.sup.4 and R.sup.5 are halogen, (halo)alkyl, (halo)alkoxy or alkylthio; r and s are 0-2; U is a bond, O, S(O).sub.0-2 or optionally substituted imino; and V is a bond CO, SO.sub.2, --CQ--T-- or --CT'.dbd.N--; or U+V together are a double bond; and R.sup.6 is as defined in the description. The invention furthermore relates to processes for their preparation and to their use as pesticides and fungicides.Type: GrantFiled: October 11, 1995Date of Patent: January 12, 1999Assignee: Hoechst Schering AgrEvo GmbHInventors: Wolfgang Schaper, Rainer Preuss, Peter Braun, Manfred Kern, Werner Knauf, Burkhard Sachse, Ulrich Sanft, Anna Waltersdorfer, Werner Bonin, Adolf Linkies, Dieter Bernd Reuschling
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Patent number: 5859020Abstract: The invention relates to substituted 4-alkoxypyrimidines of the formula ##STR1## in which R.sup.1 is hydrogen, halogen, alkyl or cycloalkyl, R.sup.2 is hydrogen, optionally substituted alkyl, optionally substituted alkoxy, optionally substituted alkylthio, alkylamino or dialkylamino, R.sup.3 is hydrogen, alkyl, alkoxy, haloalkoxy, halogen, alkylthio, amino, alkylamino or dialkylamino, and R.sup.4 is hydrogen, alkyl, cycloalkyl or haloalkyl, where R.sup.2 and R.sup.3 together with the carbon atoms to which they are attached can also form a ring, and Q is as defined in the description.The invention furthermore relates to a process for their preparation, to agents containing them, and to their use as pesticides.Type: GrantFiled: January 15, 1997Date of Patent: January 12, 1999Assignee: Hoechst Schering AgrEvo GmbHInventors: Rainer Preuss, Gerhard Salbeck, deceased, Wolfgang Schaper, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lummen
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Patent number: 5824874Abstract: The polypeptide with the sequence (SEQ ID NO:1)Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln -Ser-Gly-Lys-Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Al a-Lys-Cys-Glu-Phe-Asp-Ser-Tyr-Lys-Gly-Lys-Cys-Tyr-Cyscan be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent.Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.Type: GrantFiled: July 29, 1996Date of Patent: October 20, 1998Assignee: Hoechst AktiengesellschaftInventors: Norbert Ulbrich, Rolf Hilgenfeld, Heinz Hanel, Burkhard Sachse, Peter Braun, Joachim Wink, Peter Eckes, Jurgen Logemann, Jozef Schell
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Patent number: 5821244Abstract: Condensed nitrogen heterocycles, process for their preparation, and their use as antimycoticsThe invention relates to compounds of the formula ##STR1## in which two of the symbols A, B, D and E in each case are CR.sup.1 and the remaining two symbols are in each case CH or in each case nitrogen or one of the remaining two symbols is CH and the other is nitrogen and one of the symbols V and W is CR.sup.2 and the other is CH or nitrogen, R.sup.1 and R.sup.2 are in each case H, halogen, alkyl, alkoxy, haloalkyl or haloalkoxy, X is optionally substituted imino, S, SO or SO.sub.2, Y is a bond or alkanediyl, Q is substituted cycloalkyl or substituted 4-piperidinyl, to processes for the preparation, to compositions containing them, and to their use as pesticides, fungicides and antimycotic agents.Type: GrantFiled: January 11, 1996Date of Patent: October 13, 1998Assignee: Hoechst Schering AgrEvo GmbHInventors: Wolfgang Schaper, Martin Markl, Rainer Preuss, Robert Klein, Gerhard Salbeck, deceased, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lummen, Werner Bonin
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Patent number: 5723450Abstract: The invention relates to compounds of the formula ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are H, halogen, an aliphatic radical or an aromatic radical, X is O, S or optionally substituted imino, Y is a bond or an optionally substituted bivalent hydrocarbon radical and Z is optionally substituted cycloalkyl or cycloalkenyl. The invention furthermore relates to processes for their preparation and their use as pesticides, in particular as insecticides, acaricides and fungicides.Type: GrantFiled: September 12, 1994Date of Patent: March 3, 1998Assignee: Hoechst Schering AgrEvo GmbHInventors: Dieter Bernd Reuschling, Adolf Heinz Linkies, Volkmar Wehner, Rainer Preuss, Wolfgang Schaper, Harald Jakobi, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lummen, Werner Bonin
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Patent number: 5691321Abstract: Heterocyclylamino- and heterocyclyloxy-cycloalkyl derivatives, their preparation, and their use as pesticides and fungicides ##STR1## in which Ar is optionally substituted 4-pyridyl or 4-pyrimidinyl; X is NH, O or S; E is a bond or alkanediyl; n is 2-7; R.sup.4 is H or alkyl, Y is O or a bond; and Ac is acyl, and salts thereof. The invention furthermore relates to processes for their preparation, to compositions comprising them, and to their use as pesticides and fungicides.Type: GrantFiled: May 15, 1995Date of Patent: November 25, 1997Assignee: Hoechst Schering AgrEvo GmbHInventors: Wolfgang Schaper, Rainer Preuss, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lummen, Werner Bonin
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Patent number: 5650417Abstract: Substituted pyridines, their preparation, and their use as pesticides and fungicides.The invention relates to compounds of the formula ##STR1## and to salts thereof in which 1, 2, 3 or 4 of the radicals R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are an aliphatic, alicyclic or araliphatic radical bonded by a --O--CH.sub.2 -- or --O--CO--, and the remaining ones of these radicals are H, halogen or an aliphatic or aromatic radical, X is O, S or optionally substituted imino, Y is a bond or a bivalent radical and Z is an aromatic radical or optionally substituted cycloalkyl or cycloalkenyl. The invention furthermore relates to processes for their preparation and to their use as pesticides, in particular as insecticides, acaricides and fungicides.Type: GrantFiled: September 12, 1994Date of Patent: July 22, 1997Assignee: Hoechst Schering AgrEvo GmbHInventors: Dieter Bernd Reuschling, Adolf Heinz Linkies, Volkmar Wehner, Rainer Preuss, Wolfgang Schaper, Harald Jakobi, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter Lummen, Werner Bonin
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Patent number: 5595992Abstract: Substituted pyridines and pyrimidines, processes for their preparation and their use as pesticides and fungicides.The invention relates to compounds of the formula ##STR1## in which A is N or CH, R is H, halogen, alkyl or cycloalkyl, R.sup.2 and R.sup.3 are H, halogen or an aliphatic radical or together form a ring, X is O, NH Or S(O).sub.q where q=0, 1 or 2, R.sup.4.sub.q is 0-4 radicals selected from the series consisting of halogen, optionally substituted alkyl or alkoxy, cycloalkyl and optionally substituted phenyl, n=0-2, m=1-3 and Y is optionally substituted methylene or imino.The invention furthermore relates to a process for their preparation and for their use as pesticides, in particular as insecticides, acaricides and fungicides. The compounds are furthermore suitable for controlling nematodes, helminths and molluscs, and for controlling endoparasites and ectoparasites in the field of veterinary medicine.Type: GrantFiled: September 12, 1994Date of Patent: January 21, 1997Assignee: Hoechst Schering AgrEvo GmbHInventors: Rainer Preuss, Wolfgang Schaper, Martin M arkl, Harald Jakobi, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter L ummen, Werner Bonin
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Patent number: 5589624Abstract: The polypeptide with the sequence (SEQ ID NO: 1)______________________________________ Ala--Thr--Tyr--Asn--Gly--Lys--Cys--Tyr--Lys--Lys--Asp-- Asn--Ile--Cys--Lys--Tyr--Lys--Ala--Gln--Ser--Gly--Lys-- Thr--Ala--Ile--Cys--Lys--Cys--Tyr--Val--Lys--Lys--Cys-- Pro--Arg--Asp--Gly--Ala--Lys--Cys--Glu--Phe--Asp--Ser-- Tyr--Lys--Gly--Lys--Cys--Tyr--Cys ______________________________________can be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent.Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.Type: GrantFiled: January 13, 1995Date of Patent: December 31, 1996Assignee: Hoechst AktiengesellschaftInventors: Norbert Ulbrich, Rolf Hilgenfeld, Heinz Hanel, Burkhard Sachse, Peter Braun, Joachim Wink, Peter Eckes, Jurgen Logemann, Jozef Schell
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Patent number: 5571815Abstract: The invention relates to compounds of the formula ##STR1## in which R.sup.1, R.sup.2, R.sup.3 and Q are as defined in the description, X is NH or oxygen and E is a bond or a 1- to 4-membered carbon chain, to a process for their preparation, to agents containing them, and to their use in the control of pests and as fungicides.Type: GrantFiled: March 11, 1993Date of Patent: November 5, 1996Assignee: Hoechst AktiengesellschaftInventors: Wolfgang Schaper, Rainer Preuss, Gerhard Salbeck, deceased, Peter Braun, Werner Knauf, Burkhard Sachse, Anna Waltersdorfer, Manfred Kern, Peter L ummen, Werner Bonin
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Patent number: 5424480Abstract: The invention relates to novel N-alkoxycinnamamides of the formula I ##STR1## in which R.sup.1 and R.sup.2 are alkyl, alkenyl, alkynyl, alkoxyalkyl, alkoxyalkenyl, alkoxyalkynyl, trialkylsilylalkynyl or arylalkyl, aryl optionally being substituted by alkyl, alkoxy, haloalkyl, haloalkoxy, alkoxycarbonyl, halogen, cyano, nitro, alkylsulfonyl, phenyl and/or phenoxy, to processes for their preparation, to fungicidal compositions containing them, and to their use as fungicides.Type: GrantFiled: December 6, 1993Date of Patent: June 13, 1995Assignee: Hoechst AktiengesellschaftInventors: Jan Vermehren, Gunther Heubach, Peter Braun, Burkhard Sachse
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Patent number: 5421839Abstract: Antifungal polypeptide and process for its productionThe polypeptide with the sequence (SEQ ID NO: 1)Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln -Ser-Gly-Lys-Thr-Ala-Ile-Cys- Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Ala-Lys-Cys-Glu-Phe-Asp-Ser-Ty r-Lys-Gly-Lys-Cys-Tyr-Cyscan be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent.Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.Type: GrantFiled: October 30, 1992Date of Patent: June 6, 1995Assignee: Hoechst AktiengesellschaftInventors: Norbert Ulbrich, Rolf Hilgenfeld, Heinz Hanel, Burkhard Sachse, Peter Braun, Joachim Wink, Peter Eckes, Jurgen Logemann, Jozef Schell
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Patent number: 5324710Abstract: Compounds of the formula I or their salts ##STR1## in which R.sup.1 to R.sup.6, W, X, a and b are as defined in claim 1 and L is a heterocyclic or isocyclic aromatic radical having 5 to 6 ring atoms, which can be condensed with an aromatic or non-aromatic 5- or 6-membered ring, where the radical can be unsubstituted or substituted, and a, b and c independently of one another are 0 or 1, are suitable as herbicides, plant growth regulators and fungicides. They can be prepared by the processes defined herein, it being possible in some cases to use novel intermediates.Type: GrantFiled: April 21, 1992Date of Patent: June 28, 1994Assignee: Hoechst AktiengesellschaftInventors: Oswald Ort, Lothar Willms, Klaus Bauer, Hermann Bieringer, Arno Schulz, Burkhard Sachse, Peter Braun
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Patent number: 5250530Abstract: Aminopyrimidine derivatives, their preparation, and agents containing them, and their use as fungicides comprising ##STR1## in which R.sup.1 is alkyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl, alkenyl, alkynyl, cycloalkylalkyl, substituted aminoalkyl, phenyl, phenylalkyl, phenoxyalkyl, phenylmercaptoalkyl or phenoxyphenoxyalkyl, R.sup.2, R.sup.3 and R.sup.4 are H, alkyl, or phenyl, R.sup.5 is H, alkyl, cycloalkyl, cycloalkylalkyl, haloalkyl, alkoxy, alkylthio, alkoxyalkyl, R.sup.7 R.sup.8 N-,alkylthioalkyl, R.sup.7 R.sup.8 N-alkyl, halogen, alkenyl, alkynyl, phenyl, phenoxy, phenylalkyl, phenoxyalkyl, phenylmercaptoalkyl, phenylmercapto, phenylalkoxy or phenylalkylthio, R5 is H, alkyl, alkyloxy, alkenyloxy, alkynyloxy, alkylthio, halogen, or phenyl or R.sup.5 and R.sup.6 together form a chain, and R.sup.7 and R.sup.8 are H, alkyl, alkoxyalkyl, hydroxyalkyl, alkylthioalkyl, alkenyl, substituted formyl, phenyl or phenylalkyl, or R.sup.7 or R.sup.Type: GrantFiled: July 9, 1990Date of Patent: October 5, 1993Assignee: Hoechst AktiengesellschaftInventors: Wolfgang Giencke, Burkhard Sachse, Heinrich Wicke
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Patent number: 5164393Abstract: Pyrimidine derivatives of the formula I ##STR1## in which the variables are herein below described in the specification. R.sup.3, R.sup.4 and R.sup.5 optionally together with the radical R.sup.3 are a component of a maximally unsaturated .lambda.-membered ring where .lambda. is 3 to 8, two radicals R.sup.6 to R.sup.9 together may form a component of an unsaturated or saturated m-membered ring where m is 5 or 6,k is 0, 1 or 2,n is 1 or 2and the addition salts thereof, their preparation, compositions containing them, and their use in the control of harmful fungi.Type: GrantFiled: October 15, 1991Date of Patent: November 17, 1992Assignee: Hoechst AktiengesellschaftInventors: Jan Vermehren, Wolfgang Giencke, Peter Braun, Burkhard Sachse
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Patent number: 5158888Abstract: Streptomyces parvullus, DSM 3816, produces on aerobic fermentation new antibiotics which are distinguished by antimicrobial activity even after derivatization.Type: GrantFiled: February 19, 1992Date of Patent: October 27, 1992Assignee: Hoechst AktiengesellschaftInventors: Peter Hammann, Susanne Grabley, Hartmut Voelskow, Burkhard Sachse, Wolfgang Raether, Carlo Giani, Gerhard Seibert
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Patent number: 5100890Abstract: Arylmethylazoles of the formula I ##STR1## in which Aryl is (substituted) phenyl or naphthyl;Z is CH or N;R.sup.1 and Q are H or alkyl;R.sup.2 is H, alk(en)yl or alkynyl;R.sup.3 and R.sup.4 are H, alkyl or other hydrocarbons; orR.sup.3 and R.sup.4 together are a--(CH.sub.2).sub.2-11 chain or a bridged--(CH.sub.2).sub.4-5 chain,and their acid addition salts, stereoisomers and optically active enantiomers possess outstanding antimycotic and antidepressant activity.They are obtained, inter alia, from arylmethylazoles II ##STR2## which are reacted with a strong base and then with a carbonyl compound III O.dbd.CR.sup.3 R.sup.4 ; thereafter, the product is reacted with the protic acid or with an alkyl halide IV R.sup.2 Hal.If desired, the products are converted to the acid addition salts, or the stereoisomers or optically active enantiomes are resolved.Type: GrantFiled: September 25, 1989Date of Patent: March 31, 1992Assignee: Hoechst AktiengesellschaftInventors: Herbert Siegel, Klaus-Dieter Kampe, Hans-Georg Alpermann, Hermann J. Gerhards, Patricia Usinger, Ulrich Schacht, Margret Leven, Wolfgang Raether, Walter Dittmar, Burkhard Sachse