Patents by Inventor Burt E. Anderson

Burt E. Anderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Activity of new N-acylated ciprofloxacin derivatives against faculative intracellular bacteria
    Patent number: 8143398
    Abstract: Bartonella species are facultative intracellular pathogens responsible for a range of diseases in animals and in humans. A selection of N-acyl ciprofloxacin analogues, chemically synthesized from ciprofloxacin, have been tested in vitro for activity against Bartonella species as models for therapeutic development. Nine Bartonella strains, including five of B. henselae, two of B. quintana, and one each of B. elizabethae and B. vinsonii, have been tested for susceptibility to different N-acyl ciprofloxacin derivatives. Several techniques have been used to test the in vitro antibacterial activity of the derivatives. Seven of them, labeled RC4-125, RC4-143, RC4-147, RC5-28, RC5-29, RC5-32 and RC5-69 showed significant intracellular anti-Bartonella activity. These synthetically derived N-acyl ciprofloxacin derivatives may be useful in the therapeutic treatment of infections caused by Bartonella.
    Type: Grant
    Filed: February 22, 2011
    Date of Patent: March 27, 2012
    Assignee: University of South Florida
    Inventors: Edward Turos, Burt E. Anderson, Ryan Scott Cormier, John C. Thomas, Rebecca J. Kapolka, Glenn Roma
  • Compositions for diagnosing Rochalimaea henselae and Rochalmaea quintana infection
    Patent number: 6406887
    Abstract: Fusion protein compositions containing the sequence of a 17 kilodalton antigenic polypeptide of Rochalimaea (SEQ ID NO:12) are disclosed for diagnosis of cat scratch disease and bacillary angiomatosis by detection of antibodies specifically binding to the polypeptide.
    Type: Grant
    Filed: March 14, 2000
    Date of Patent: June 18, 2002
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Burt E. Anderson, Russell L. Regnery
  • Nucleic acids of rochalimaea henselae and methods and compositions for diagnosing rochalimaea henselae and rochalimaea quintana infection
    Publication number: 20020012919
    Abstract: A method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an antigenic fragment thereof in the subject is provided. Also provided is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier. A method of diagnosing Rochalimaea quintana infection in a subject by detecting the presence of a nucleic acid specific to Rochalimaea quintana in a sample from the subject is provided. A purified, 60-kDa heat shock protein of Rochalimaea is provided. Also provided is a 17-kDa antigenic polypeptide of Rochalimaea.
    Type: Application
    Filed: December 29, 2000
    Publication date: January 31, 2002
    Applicant: The Government of the United States, Department of Health and Human Services
    Inventors: Burt E. Anderson, Russell L. Regnery
  • Nucleic acids of Rochalimaea henselae and methods and compositions for diagnosing Rochalimaea henselae and Rochalimaea quintana infection
    Patent number: 5736347
    Abstract: A method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an antigenic fragment thereof in the subject is provided. Also provided is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier. A method of diagnosing Rochalimaea quintana infection in a subject by detecting the presence of a nucleic acid specific to Rochalimaea quintana in a sample from the subject is provided. A purified, 60-kDa heat shock protein of Rochalimaea is provided. Also provided is a 17-kDa antigenic polypeptide of Rochalimaea.
    Type: Grant
    Filed: September 16, 1994
    Date of Patent: April 7, 1998
    Assignee: The United States of America as represented by the Department of Health and Human Resources
    Inventors: Burt E. Anderson, Russell L. Regnery
  • Nucleic acids specific for Rochalimaea quintana
    Patent number: 5693776
    Abstract: A method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an immunogenically specific determinant thereof in the subject is provided. Also provided is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier. A method of diagnosing Rochalimaea quintana infection in a subject by detecting the presence of a nucleic acid specific to Rochalimaea quintana in a sample from the subject is provided. A purified heat shock protein of Rochalimaea is provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 2, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Burt E. Anderson, Russell L. Regnery
  • Compositions for diagnosing rochalimaea henselae and rochalimaea quintana infection
    Patent number: 5644047
    Abstract: A method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an immunogenically specific determinant thereof in the subject is provided. Also provided is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier. A method of diagnosing Rochalimaea quintana infection in a subject by detecting the presence of a nucleic acid specific to Rochalimaea quintana in a sample from the subject is provided. A purified heat shock protein of Rochalimaea is provided.
    Type: Grant
    Filed: May 18, 1994
    Date of Patent: July 1, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Burt E. Anderson, Russell L. Regnery
  • Methods and compositions for diagnosing cat scratch disease and bacillary angiomatosis caused by Rochalimaea henselae
    Patent number: 5399485
    Abstract: The present invention relates to a method of diagnosing cat scratch disease and a method of diagnosing bacillary angiomatosis in a subject by detecting the presence of Rochalimaea henselae or an immunogenically specific determinant thereof in the subject. Also provided by the present invention is a vaccine comprising an immunogenic amount of a nonpathogenic Rochalimaea henselae or an immunogenically specific determinant thereof and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: January 17, 1992
    Date of Patent: March 21, 1995
    Assignee: United States of America
    Inventors: Russell L. Regnery, Burt E. Anderson