Patents by Inventor Burton K. Wasson

Burton K. Wasson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Quinolinyl ethanolamines
    Patent number: 4348398
    Abstract: Heterocyclic ethanolamines of the formulaHet--CHOH--CH.sub.2 --NH--aralkylwhere het is a 10 membered N heterocycle are disclosed. The compounds are useful as pharmaceuticals.
    Type: Grant
    Filed: December 23, 1980
    Date of Patent: September 7, 1982
    Assignee: Merck Sharp & Dohme (I.A.) Corp.
    Inventors: Joseph G. Atkinson, Burton K. Wasson
  • 2-(3-Substituted amino-2-hydroxypropoxy)-3-piperidino pyrazines for use in treating hypertension
    Patent number: 4343802
    Abstract: 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds optionally having substituents in the 5 and/or 6 positions, possessing .beta.-adrenergic blocking properties are described. The products are prepared by reaction of a 2-chloro (or hydroxy) pyrazine with a 5-hydroxymethyl (or sulfonyloxymethyl) oxazolidine followed by acid hydrolysis.
    Type: Grant
    Filed: July 3, 1980
    Date of Patent: August 10, 1982
    Assignee: Merck, Sharp & Dohme (I.A.) Corp.
    Inventors: Burton K. Wasson, Leonard M. Weinstock
  • 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds and compositions
    Patent number: 4193995
    Abstract: 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazine compounds optionally having substituents in the 5 and/or 6 positions, possessing .beta.-adrenergic blocking properties are described. The products are prepared by reaction of a 2-chloro(or hydroxy)pyrazine with a 5-hydroxymethyl(or sulfonyloxymethyl)oxazolidine followed by acid hydrolysis.
    Type: Grant
    Filed: March 8, 1977
    Date of Patent: March 18, 1980
    Assignee: Merck Sharp & Dohme (I.A.) Corp.
    Inventors: Burton K. Wasson, Leonard M. Weinstock
  • 3-Hydroxy-3-(1,2,5-thiadiazolyloxyalkanol)-3,4-dihydro-2H-1,5-ben zodioxepin products
    Patent number: 3944560
    Abstract: 3-Hydroxy-3-(substituted-aminoalkyl-3,4-dihydro-2H-1,5-benzodioxepin products are described that exhibit .sym.-advenergic stimulating properties and are therefore suitable for use as bronchodilating agents. The products are prepared essentially by four principal routes from 3-oxo-3,4-dihydro-2H-1,5-benzodioxepins. By one route the 3-oxobenzodioxepin is treated with a nitroalkane to give a 3-hydroxy-3-nitroalkyl-benzodioxepin the nitro group of which is reduced to an amine and the resulting compound reacted with an aldehyde or ketone under hydrogenating conditions to introduce the desired substituent into the amino function.
    Type: Grant
    Filed: November 21, 1973
    Date of Patent: March 16, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Burton K. Wasson, Haydn W. R. Williams