Abstract: A pharmaceutical composition containing a tyrosine kinase activity inhibitor as an active ingredient may increase the expression of sodium iodide symporter in thyroid cancer cells, thereby promoting iodine uptake and killing thyroid cancer cells. Thus, the composition may be useful for the treatment of thyroid cancer.

Abstract: A pharmaceutical composition containing a tyrosine kinase activity inhibitor as an active ingredient may increase the expression of sodium iodide symporter in thyroid cancer cells, thereby promoting iodine uptake and killing thyroid cancer cells. Thus, the composition may he useful for the treatment of thyroid cancer.

Abstract: The present invention relates to a composition for hair regeneration comprising a macrophage-derived extracellular vesicle mimetics, and since macrophage-derived extracellular vesicle mimetics are well absorbed into dermal papilla cells, have an excellent effect in promoting the proliferation of dermal papilla cells, as well as having an activity to increase the level of hair-induced proteins, it is excellent in the effects of proliferation of dermal papilla cells and hair increase and thus a composition comprising macrophage-derived extracellular vesicle mimetics can be provided for hair regeneration.

Abstract: The present invention relates to a composition for material delivery, including exosome mimetics derived from red blood cells, and a use thereof and the composition for material delivery according to an exemplary embodiment of the present invention includes exosome mimetics derived from red blood cells, which are capable of being loaded with a drug, a radioactive material, or a fluorescent material, and thus may be usefully utilized for a drug delivery use, a cell labeling use, a contrast medium, or the like, and when the composition for material delivery according to an exemplary embodiment of the present invention is used, treatment and diagnosis may be simultaneously performed.

Abstract: An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided.

Abstract: A pharmaceutical composition containing a tyrosine kinase activity inhibitor as an active ingredient may increase the expression of sodium iodide symporter in thyroid cancer cells, thereby promoting iodine uptake and killing thyroid cancer cells. Thus, the composition may be useful for the treatment of thyroid cancer.

Abstract: The present invention relates to a composition for material delivery, including exosome mimetics derived from red blood cells, and a use thereof and the composition for material delivery according to an exemplary embodiment of the present invention includes exosome mimetics derived from red blood cells, which are capable of being loaded with a drug, a radioactive material, or a fluorescent material, and thus may be usefully utilized for a drug delivery use, a cell labeling use, a contrast medium, or the like, and when the composition for material delivery according to an exemplary embodiment of the present invention is used, treatment and diagnosis may be simultaneously performed.

Abstract: An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided.

Abstract: An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided.

Abstract: Provided is an automatic salivation facilitating apparatus including a first parotid gland massaging device which massages user's one-side parotid gland, a second parotid gland massaging device which massages user's other-side parotid gland, a first fixing member which connects the first and second parotid gland massaging devices and allows the user to wear the automatic salivation facilitating apparatus, a salivation agent injection unit which is disposed to a lower portion of one of the first and second parotid gland massaging devices to periodically automatically inject salivation agent, and a controller which operates a main body. The automatic salivation facilitating apparatus utilizes a submandibular gland massaging device together with the salivation agent injection unit and the parotid gland massaging devices, so that the effect of facilitating salivation can be maximized.

Abstract: Provided is an automatic salivation facilitating apparatus including a first parotid gland massaging device which massages user's one-side parotid gland, a second parotid gland massaging device which massages user's other-side parotid gland, a first fixing member which connects the first and second parotid gland massaging devices and allows the user to wear the automatic salivation facilitating apparatus, a salivation agent injection unit which is disposed to a lower portion of one of the first and second parotid gland massaging devices to periodically automatically inject salivation agent, and a controller which operates a main body. The automatic salivation facilitating apparatus utilizes a submandibular gland massaging device together with the salivation agent injection unit and the parotid gland massaging devices, so that the effect of facilitating salivation can be maximized.

Abstract: A specific targeting peptide binding to glypican-3 can specifically binds to glypican-3 overexpressed in carcinoma cells and includes an amino acid sequence represented by SEQ ID NO:1 or some thereof. Glypican-3 is overexpressed in malignant tumors including hepatocellular carcinoma, melanoma, germ cell tumor, etc., and may be targeted in diagnosis and treatment of tumors by labeling the targeting peptide. A diagnosis using the specific peptide may detect even small tumors more accurately than conventional methods. A treatment method using the specific peptide may remove only carcinoma cells without harming other normal tissues.

Abstract: An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided.

Abstract: A specific targeting peptide binding to glypican-3 can specifically binds to glypican-3 overexpressed in carcinoma cells and includes an amino acid sequence represented by SEQ ID No. 1 or some thereof. Glypican-3 is overexpressed in malignant tumors including hepatocellular carcinoma, melanoma, germ cell tumor, etc., and may be targeted in diagnosis and treatment of tumors by marking the targeting peptide. A diagnosis using the targeting peptide may detect even small tumors more accurately than conventional methods. A treatment method using the targeting peptide may remove only carcinoma cells without harming other normal tissues.

Abstract: A recombinant vector capable of expressing MDR1 shRNA and thymidine kinase, and a use thereof. More specifically, provided is a recombinant vector capable of efficiently expressing MDR1 shRNA and thymidine kinase in a host cell, a transfectant cell comprising the same recombinant vector, a composition for treating neoplastic diseases, comprising the same recombinant vector, and a method for imaging of neoplastic lesions using the same recombinant vector. The recombinant vector of the present invention is capable of achieving efficient intracellular expression of MDR1 shRNA and a thymidine kinase-GFP fusion protein within the host cell and is therefore highly effective for combined therapy of anticancer drugs. Further, the recombinant vector of the present invention enables imaging of neoplastic lesions. Therefore, the recombinant vector of the present invention can be used in combination with other anticancer drugs for treatment of neoplastic diseases.

Abstract: The present invention relates to method and apparatus of analyzing a wired/wireless communication network to optimize performance of the network. In the present invention, data are continuously gathered from all elements constituting a wired/wireless communication network and are analyzed to find an element of which performance and/or efficiency deteriorates. If found, an optimal plan to resolve low performance and/or efficiency is chosen through the data analysis and is then provided in real time. The present invention also relates to a recording medium storing computer programs to conduct said procedures.