Publication number: 20180099019
Abstract: The present disclosure provides Diels-Alder adducts of chalcone and prenylphenyl moieties capable of modulating the activity of cannabinoid receptors, and to oligomers of flavan-3-ol capable of modulating fat absorption and storage. Such Diels-Alder adducts of chalcone and prenylphenyl moieties or oligomers of flavan-3-ol can optionally be used in combination with other weight management agents, such as anorectic agents, a lipase inhibitors, other cannabinoid receptor modulators, psychotropic agents, insulin sensitizers, stimulants, or satiety agents, as well as to methods of use thereof such as treating or preventing weight gain or obesity, promoting weight loss, appetite suppression, modifying satiety, or the like.
Type:
Application
Filed:
December 11, 2017
Publication date:
April 12, 2018
Applicants:
Unigen, Inc., Unigen, Inc.
Inventors:
Lidia Alfaro Brownell, Byong-II Choi, Brandon Corneliusen, Mei-Feng Hong, Eu-Jin Hyun, QI Jia, Ping Jiao, Hyun-Jin Kim, Mi-Ran Kim, Tae-Woo Kim, Bo-Su Lee, Young-Chul Lee, Jeong-Bum Nam, Mesfin Yimam, Ji-Hye Hwang, Mi-Sun Oh