Patents by Inventor Byong Sung Kwak
Byong Sung Kwak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8901116Abstract: There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Formula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain, anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.Type: GrantFiled: September 16, 2013Date of Patent: December 2, 2014Assignee: SK Biopharmaceuticals Co., Ltd.Inventors: Byong Sung Kwak, Hong Sik Moon, Han-Ju Yi, Young Soon Kang, Dae Joong Im, Eun Hee Chae, Sang Mi Chae, Ki Ho Lee
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Publication number: 20140088095Abstract: There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Formula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain, anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.Type: ApplicationFiled: September 16, 2013Publication date: March 27, 2014Applicant: SK Biopharmaceuticals Co., Ltd.Inventors: Byong Sung KWAK, Hong Sik MOON, Han-Ju YI, Young Soon KANG, Dae Joong IM, Eun Hee CHAE, Sang Mi CHAE, Ki Ho LEE
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Patent number: 8541409Abstract: There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Formula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain, anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.Type: GrantFiled: April 30, 2008Date of Patent: September 24, 2013Assignee: SK Biopharmaceuticals Co., Ltd.Inventors: Byong Sung Kwak, Hong Sik Moon, Han Ju Yi, Young Soon Kang, Dae Joong Im, Eun Hee Chae, Sang Mi Chae, Ki Ho Lee
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Patent number: 8206576Abstract: The present invention relates to a nickel-based catalyst using hydrotalcite-like precursor and a steam reforming reaction by using the catalyst, and particularly to a nickel-based catalyst prepared by dispersing nickel uniformly onto the inner part and the surface of the support through a substitution between the magnesium and the active nickel metal and optimizing the molar ratios of nickel, magnesium and aluminum in order to utilize nickel as an active metal and a hydrotalcite-like precursor consisting of aluminum and magnesium, which shows an increased specific surface area of the catalyst and surface area of the active nickel, and thus enables the production of hydrogen-rich gas in high yield during the steam reforming reaction of LPG with superior maintenance of catalytic activity for a long period of time due to the inhibition of carbon deposition.Type: GrantFiled: October 9, 2006Date of Patent: June 26, 2012Assignee: SK Innovation Co., Ltd.Inventors: Dong Ju Moon, Dae Hyun Kim, Jung Shik Kang, Jong Woo Ryu, Byung Gwon Lee, Young-Seek Yoon, Byong-Sung Kwak
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Patent number: 8124796Abstract: Disclosed is a method of preparing 3-hydroxytetrahydrofuran using cyclodehydration. More particularly, this invention relates to a method of preparing 3-hydroxytetrahydrofuran, including subjecting 1,2,4-butanetriol to cyclodehydration under reaction conditions of a reaction temperature of 30˜180° C. and reaction pressure of 5000 psig or less in the presence of a strong acid cation exchange resin catalyst having a sulfonic acid group as an exchange group. According to the method of this invention, 3-hydroxytetrahydrofuran can be economically prepared at higher yield and productivity than when using conventional methods.Type: GrantFiled: January 10, 2006Date of Patent: February 28, 2012Assignee: SK Biopharmaceuticals Co., Ltd.Inventors: Byong Sung Kwak, Tae Yun Kim, Jin Woong Kim, Sang Il Lee, Ki Ho Koh
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Publication number: 20110195963Abstract: There is provided a novel carbamoyloxy arylalkanoyl arylpiperazine derivative compound having abundant racemic or enantiomeric characteristics, represented by the Formula 1, and pharmaceutically available salts or hydrates thereof. Also, there are provided a pharmaceutical composition for treating pain, anxiety or depression including an effective amount of the compound, and a method for treating pain, anxiety or depression in mammals by administering an effective amount of the compound to the mammals in need of treatment thereof.Type: ApplicationFiled: April 30, 2008Publication date: August 11, 2011Inventors: Byong Sung Kwak, Hong Sik Moon, Han Ju Yi, Young Soon Kang, Dae Joong Im, Eun Hee Chae, Sang Mi Chae, Ki Ho Lee
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Patent number: 7919424Abstract: Disclosed herein are a platinum-based catalyst for oxidation/reduction reactions and the use thereof. The platinum-based catalyst is prepared by loading a catalyst composition comprising a water soluble salt of at least one metal selected from among cerium (Ce), zirconium (Zr) and rhenium (Re), on a support comprising at least one selected from among alumina, silica and titania. The disclosed catalyst can be prepared in a simple manner without any particular limitation as to the kind of usable water soluble platinum salt, and when it is applied to various oxidation reactions, including water gas shift reactions of carbon monoxide, three-way catalytic reactions, and selective oxidation reactions of carbon monoxide, and to reduction reactions, such as reactions of removing nitrogen oxide (NOx), it will show excellent catalytic activity.Type: GrantFiled: July 30, 2009Date of Patent: April 5, 2011Assignee: SK Energy Co., Ltd.Inventors: Byong Sung Kwak, Young Seek Yoon, Jin Hong Kim, Mee Sook Lim
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Patent number: 7838455Abstract: Disclosed herein is a method of regenerating a titanium-containing molecular sieve catalyst. Particularly, this invention provides a method of regenerating a titanium-containing molecular sieve catalyst used in epoxidation of olefin through simple treatment using a mixture solvent comprising aqueous hydrogen peroxide and alcohol. According to the method of this invention, when the catalyst having decreased activity is regenerated, the activity of the regenerated catalyst is equal to that of new catalyst and can be maintained stable for a long period of time.Type: GrantFiled: June 26, 2006Date of Patent: November 23, 2010Assignee: SK Energy Co., Ltd.Inventors: Byong Sung Kwak, Seung Hoon Oh, Tae Jin Kim, Dae Hyun Choo, Young Min Chung
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Patent number: 7678902Abstract: Disclosed is a process for the preparation of 11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine. In the process, low-priced 2,2?-dithiosalicylic acid as starting material is subjected to bond formation reaction with 1-chloro-2-nitrobenzene in a basic aqueous solution, a nitro group reduction reaction is conducted, cyclization and chlorination reactions are simultaneously carried out in the presence of a equivalent amount of halogenating agent, a reaction with piperazine is continuously conducted without separation, and a reaction with 2-haloethoxyethanol is conducted, thereby it is possible to economically producing Quetiapine, that is, 11-(4-[2-(2-hydroxyethoxy)ethyl]-1-piperazinyl)-dibenzo[b,f][1,4]thiazepine, in an environmentally friendly manner.Type: GrantFiled: June 17, 2005Date of Patent: March 16, 2010Assignee: SK Holdings Co., Ltd.Inventors: Byong-Sung Kwak, Sang-Il Lee, Hee-Jun Hwang, Jong-Ho Lim
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Publication number: 20100004120Abstract: Disclosed herein are a platinum-based catalyst for oxidation/reduction reactions and the use thereof. The platinum-based catalyst is prepared by loading a catalyst composition comprising a water soluble salt of at least one metal selected from among cerium (Ce), zirconium (Zr) and rhenium (Re), on a support comprising at least one selected from among alumina, silica and titania. The disclosed catalyst can be prepared in a simple manner without any particular limitation as to the kind of usable water soluble platinum salt, and when it is applied to various oxidation reactions, including water gas shift reactions of carbon monoxide, three-way catalytic reactions, and selective oxidation reactions of carbon monoxide, and to reduction reactions, such as reactions of removing nitrogen oxide (NOx), it will show excellent catalytic activity.Type: ApplicationFiled: July 30, 2009Publication date: January 7, 2010Applicant: SK Energy Co., Ltd.Inventors: Byong Sung Kwak, Young Seek Yoon, Jin Kim Kim, Mee Sook Lim
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Publication number: 20090261020Abstract: The present invention relates to a nickel-based catalyst using hydrotalcite-like precursor and a steam reforming reaction by using the catalyst, and particularly to a nickel-based catalyst prepared by dispersing nickel uniformly onto the inner part and the surface of the support through a substitution between the magnesium and the active nickel metal and optimizing the molar ratios of nickel, magnesium and aluminum in order to utilize nickel as an active metal and a hydrotalcite-like precursor consisting of aluminum and magnesium, which shows an increased specific surface area of the catalyst and surface area of the active nickel, and thus enables the production of hydrogen-rich gas in high yield during the steam reforming reaction of LPG with superior maintenance of catalytic activity for a long period of time due to the inhibition of carbon deposition.Type: ApplicationFiled: October 9, 2006Publication date: October 22, 2009Inventors: Dong Ju Moon, Dae Hyun Kim, Jung Shik Kang, Jong Woo Ryu, Byung Gwon Lee, Young-Seek Yoon, Byong-Sung Kwak
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Publication number: 20090018291Abstract: Disclosed herein is a method of regenerating a titanium-containing molecular sieve catalyst. Particularly, this invention provides a method of regenerating a titanium-containing molecular sieve catalyst used in epoxidation of olefin through simple treatment using a mixture solvent comprising aqueous hydrogen peroxide and alcohol. According to the method of this invention, when the catalyst having decreased activity is regenerated, the activity of the regenerated catalyst is equal to that of new catalyst and can be maintained stable for a long period of time.Type: ApplicationFiled: June 26, 2006Publication date: January 15, 2009Applicant: SK Energy Co., Ltd.Inventors: Byong-Sung Kwak, Seung Hoon Oh, Tae Jin Kim, Dae Hyun Choo, Young Min Chung
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Publication number: 20090005581Abstract: Disclosed is a method of preparing 3-hydroxytetrahydrofuran using cyclodehydration. More particularly, this invention relates to a method of preparing 3-hydroxytetrahydrofuran, including subjecting 1,2,4-butanetriol to cyclodehydration under reaction conditions of a reaction temperature of 30˜180° C. and reaction pressure of 5000 psig or less in the presence of a strong acid cation exchange resin catalyst having a sulfonic acid group as an exchange group. According to the method of this invention, 3-hydroxytetrahydrofuran can be economically prepared at higher yield and productivity than when using conventional methods.Type: ApplicationFiled: January 10, 2006Publication date: January 1, 2009Applicant: SK Holdings Co., Ltd.Inventors: Byong Sung Kwak, Tae Yun Kim, Jin Woong Kim, Sang II Lee, Ki Ho Koh
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Publication number: 20080274878Abstract: Disclosed herein are a platinum-based catalyst for oxidation/reduction reactions and the use thereof. The platinum-based catalyst is prepared by loading a catalyst composition comprising a water-soluble salt of at least one metal selected from among cerium (Ce), zirconium (Zr) and rhenium (Re), on a support comprising at least one selected from among alumina, silica and titania. The disclosed catalyst can be prepared in a simple manner without any particular limitation as to the kind of usable water-soluble platinum salt, and when it is applied to various oxidation reactions, including water gas shift reactions of carbon monoxide, three-way catalytic reactions, and selective oxidation reactions of carbon monoxide, and to reduction reactions, such as reactions of removing nitrogen oxide (NOx), it will show excellent catalytic activity.Type: ApplicationFiled: November 29, 2006Publication date: November 6, 2008Applicant: Sk Energy Co. LtdInventors: Byong Sung Kwak, Young Seek Yoon, Jin Hong Kim, Mee Sook Lim
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Publication number: 20080197051Abstract: Disclosed herein are a desulfurizing agent for removing organic sulfur compounds, a preparation method thereof, and a method for removing organic sulfur compounds using the same. The desulfurizing agent consists of a copper-zinc-aluminum complex free of alkaline metal, with a large surface area. When being contacted with organic sulfur compounds, such as t-butylmercaptan, tetrahydrothiophene, dimethylsulfide, etc., the desulfurizing agent exhibits excellent desulfurization ability and is not de-graded especially at high temperatures as high as 150˜350° C.Type: ApplicationFiled: July 31, 2006Publication date: August 21, 2008Applicant: SK ENERGY CO., LTD.Inventors: Byong Sung Kwak, Young Seek Yoon, Jin Hong Kim, Il Su Kim, Keun Seob Choi, Jin Hwan Bang, Ki Won Jun, Hyung Tae Kim, Seung Moon Kim
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Patent number: 7214793Abstract: Disclosed is a method of preparing 10H-dibenzo[b,f][1,4]thiazepin-11-one, including reacting dithiosalicylic acid with 1-chloro-2-nitrobenzene in a basic aqueous solution in the presence or absence of a reducing agent, to prepare 2-(2-nitrophenylsulfuryl)benzoic acid; subjecting the 2-(2-nitrophenylsulfuryl)benzoic acid to nitro group reduction in the presence of hydrogen, a solvent and a heterogeneous metal catalyst, to prepare 2-(2-aminophenylsulfuryl)benzoic acid; and directly cyclizing the 2-(2-aminophenylsulfuryl)benzoic acid in an organic solvent in the presence or absence of an acid catalyst. The method according to the present invention is economical due to the use of the inexpensive starting material, and also environmentally friendly and efficient by minimizing the use of the organic solvent and performing direct cyclization without the activation of carboxylic acid.Type: GrantFiled: November 26, 2003Date of Patent: May 8, 2007Assignee: SK CorporationInventors: Byong-Sung Kwak, Ki-Nam Chung, Ki-Ho Koh, Hee-Jun Hwang
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Publication number: 20070066589Abstract: Disclosed is a method of preparing 10H-dibenzo[b,f][1,4]thiazepin-11-one, including reacting dithiosalicylic acid with 1-chloro-2-nitrobenzene in a basic aqueous solution in the presence or absence of a reducing agent, to prepare 2-(2-nitrophenylsulfuryl)benzoic acid; subjecting the 2-(2-nitrophenylsulfuryl)benzoic acid to nitro group reduction in the presence of hydrogen, a solvent and a heterogeneous metal catalyst, to prepare 2-(2-aminophenylsulfuryl)benzoic acid; and directly cyclizing the 2-(2-aminophenylsulfuryl)benzoic acid in an organic solvent in the presence or absence of an acid catalyst. The method according to the present invention is economical due to the use of the inexpensive starting material, and also environmentally friendly and efficient by minimizing the use of the organic solvent and performing direct cyclization without the activation of carboxylic acid.Type: ApplicationFiled: November 26, 2003Publication date: March 22, 2007Inventors: Byong-Sung Kwak, Ki-Nam Chung, Ki-Ho Koh, Hee-Jun Hwang
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Publication number: 20060052617Abstract: Disclosed is a continuous process for the production of optically pure (S)-?-hydroxy-?-butyrolactone having constantly maintained optical activity, consisting of hydrogenating 2-50 wt % of a substituted carboxylic acid derivative in a solvent using a fixed bed reactor filled with a precious metal catalyst-impregnated inorganic oxide carrier at 50-500° C. under pressure of 15-5,500 psig at weight-space-velocity of 0.1-10 h?1, in which a molar ratio of hydrogen to carboxylic acid derivative ranges from 2 to 10. The desired material can be produced in higher optical purity and at higher yield by the current process which is relatively simpler and environmentally safer than conventional processes. Additionally, increased production efficiency leads to production of the desired material on a large scale.Type: ApplicationFiled: September 18, 2002Publication date: March 9, 2006Applicant: SK CORPORATIONInventors: Byong-Sung Kwak, Ki-Nam Chung, Tae-Yun Kim, Ki-Ho Koh, Jin-Woong Kim, Sang-Il Lee
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Publication number: 20030130525Abstract: There is disclosed a preparation method of 3-methylindole derivatives by reducing the aldehyde moiety in indole-3-carboxaldehyde derivatives in the presence of the copper or copper oxide-based hydrogenation catalyst. This process is performed in solvent under the condition of 50-300° C. and 50-1,000 psig in the presence of a solvent with a hydrogen atmosphere. The method is advantageous in the economic aspects because of the employment of a relatively inexpensive hydrogenation catalyst and the easy regeneration thereof. Further, this process is environmentally safe because the intended addition of the sulfur components is not required therefor.Type: ApplicationFiled: January 2, 2003Publication date: July 10, 2003Applicant: SK CorporationInventors: Byong-Sung Kwak, Tae-Yun Kim, Jin-Woong Kim, Sang-Il Lee
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Patent number: 6509504Abstract: Disclosed is a method for preparing serinol (2-amino-1,3-proanediol). From nitromethane, para-formaldehyde and sodium hydroxide, 1-nitro-1,3-propanediol sodium salt is prepared as a medical intermediate. In a fixed bed, this intermediate is allowed to undergo the continuous hydrogenation of 2-nitro-1,3-propanediol sodium salt and methanol as shown in reaction (1). In addition to being simple, the method is economically favorable and affords the high yield and high purity of serinol.Type: GrantFiled: December 12, 2001Date of Patent: January 21, 2003Assignee: SK CorporationInventors: Byong-Sung Kwak, Ki-Nam Chung, Choon-Gil Kim, Ki-Ho Koh