Patents by Inventor Byoung-Kwon Chun

Byoung-Kwon Chun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of nucleosides ribofuranosyl pyrimidines
    Publication number: 20080139802
    Abstract: The present process provides an improved method for converting 2?-deoxy-2?-fluoro-2?-methyl-D-ribonolactones derivatives to 3-fluoro-3-methyl-2-chlorofuran compounds which are useful for the synthesis of nucleosides and improved processes for the synthesis of the D-ribonolactone compounds.
    Type: Application
    Filed: October 10, 2007
    Publication date: June 12, 2008
    Inventors: Steven D. Axt, Byoung-Kwon Chun, Qingwu Jin, Suguna Rachakonda, Bruce Ross, Keshab Sarma, Justin Vitale, Jiang Zhu
  • Antiviral nucleosides
    Publication number: 20070197463
    Abstract: Compounds having the formula I wherein R1 is as herein defined are Hepatitis C virus NS5b polymerase inhibitors.
    Type: Application
    Filed: December 8, 2006
    Publication date: August 23, 2007
    Inventors: Byoung-Kwon Chun, Jeremy Clark, Keshab Sarma, Peiyuan Wang
  • Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives
    Publication number: 20060199783
    Abstract: The present invention provides (i) a process for preparing a 2-deoxy-2-fluoro-2-methyl-D-ribonolactone derivative, (ii) conversion of the lactone to nucleosides with potent anti-HCV activity, and their analogues, and (iii) a method to prepare the anti-HCV nucleosides containing the 2-deoxy-2-fluoro-2-C-methyl-o-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.
    Type: Application
    Filed: February 13, 2006
    Publication date: September 7, 2006
    Applicant: Pharmassett, Inc.
    Inventors: Peiyuan Wang, Wojciech Stec, Byoung-Kwon Chun, Junxing Shi, Jinfa Du
  • Preparation of 2'-fluoro-2'-alkyl-substituted or other optionally substituted ribofuranosyl pyrimidines and purines and their derivatives
    Publication number: 20060122146
    Abstract: The present invention provides (i) processes for preparing a 2?-deoxy-2?-fluoro-2?-methyl-D-ribonolactone derivatives, (ii) conversion of intermediate lactones to nucleosides with potent anti-HCV activity, and their analogues, and (iii) methods to prepare the anti-HCV nucleosides containing the 2?-deoxy-2?-fluoro-2?-C-methyl-?-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.
    Type: Application
    Filed: September 13, 2005
    Publication date: June 8, 2006
    Inventors: Byoung-Kwon Chun, Peiyuan Wang, Jinfu Du, Suguan Rachakonda
  • Compounds with the bicyclo[4.2.1]nonane system for the treatment of flavivridae infections
    Publication number: 20040082574
    Abstract: The disclosed invention is a bicyclo[4.2.1]nonane and its pharmaceutically acceptable salt or prodrug, and its composition and method of use to treat Flaviviridae (Hepacivirus, Flavivirus, and Pestivirus) infections in a host, including animals, and especially humans.
    Type: Application
    Filed: August 1, 2003
    Publication date: April 29, 2004
    Inventors: Peiyuan Wang, Lieven J. Stuyver, Kyoichi A. Watanabe, Abdalla Hassan, Byoung-Kwon Chun, Laurent Hollecker