Abstract: A method for operating a memory device includes providing a memory block including at least one source select transistor coupled between a source line and a bit line, a plurality of memory cells, and a drain select transistor, controlling a source select line coupled to the at least one source select transistor and a plurality of word lines coupled to the plurality of memory cells to be in a floating state, and applying an erase voltage to the source line and the bit line.

Abstract: A battery cell having an electrode tab with enhanced safety and improved cooling performance, and a battery module, a battery pack and a vehicle including the same is provided. The battery cell includes an electrode assembly including a cell body and an electrode tab provided to at least one side of the cell body, a cell case configured to accommodate the electrode assembly, an electrode lead drawn out of the cell case and connected to the electrode assembly through the electrode tab at a coupling portion, and a tab protection module accommodated in the cell case and covering at least a part of the electrode tab, the tab protection module including a heat dissipating material configured to discharge heat to the outside through at least a part thereof.

Abstract: The present disclosure relates to a memory device and a manufacturing method of the memory device. The memory device according to an embodiment includes a stacked structure including gate lines separated from and stacked on top of each other, a main plug formed in a vertical direction to the stacked structure, a plug separation pattern separating the main plug into first and second sub-plugs, a gap formed in the plug separation pattern; and a separation layer surrounding the gap.

Abstract: The invention is directed to reliable and efficient detection of mRNAs as well as other RNAs in living cells and its use to identify and, if desired, separate cells based on their desired characteristics Such methods greatly simplify and reduce the time necessary to carry out previously-known procedures, and offers new approaches as well, such as selecting cells that generate a particular protein or antisense oligonucleotide, generating cell lines that express multiple proteins, generating cell lines with knock-out of one or more protein, and others.

Abstract: Disclosed is a battery cell having an electrode tab with an enhanced safety, and a battery module, a battery pack and a vehicle including the same. The battery cell includes an electrode assembly including a cell body and an electrode tab provided to at least one of both sides of the cell body, a cell case configured to accommodate the electrode assembly therein, an electrode lead drawn out of the cell case by a predetermined length and connected to the electrode assembly through the electrode tab, and a tab protection module accommodated in the cell case and configured to cover at least a part of the electrode tab.

Abstract: The present invention provides a novel process for preparing a diaminopyrimidine derivative or acid addition salt thereof having an activity as a 5-HT4 receptor agonist. And also, the present invention provides novel crystalline forms of a hydrochloride of the diaminopyrimidine derivative and processes for preparing the same.

Abstract: The present invention provides a novel process for preparing a diaminopyrimidine derivative or acid addition salt thereof having an activity as a 5-HT4 receptor agonist. And also, the present invention provides novel crystalline forms of a hydrochloride of the diaminopyrimidine derivative and processes for preparing the same.

Abstract: Provided are a novel process for preparing a diaminopyrimidine derivative or acid addition salt thereof having an activity as a 5-HT4 receptor agonist, crystalline forms of a hydrochloride of the diaminopyrimidine derivative, and processes for preparing the same.

Abstract: A navigator includes: a data transceiver configured to receive and transmit changed map data including a gateway list and difference data corresponding to information related to a boundary between divided regions; a DB manager configured to separately store and manage map data for each divided region and configured to update the map data for each divided region under the control of a controller; and a controller configured to control the update of the map data for each divided region based on the gateway list transmitted from the data transceiver.

Abstract: A semiconductor device includes a memory string connected between a source line and a bit line. The memory string includes first memory cells stacked along a first channel layer, second memory cells stacked along a second channel layer, and at least one switching memory cell connected between the first memory cells and the second memory cells. A method for operating the semiconductor device includes programming a selected first memory cell among the first memory cells, selecting a second memory cell to be programmed among the second memory cells, applying a program voltage to a word line connected to the selected second memory cell, turning off the switching memory cell such that the first channel layer and the second channel layer are electrically isolated from each other, and applying a pass voltage to word lines connected to unselected memory cells among the first and second memory cells.

Abstract: Provided are a novel process for preparing (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine or a salt thereof, which is an intermediate useful for the preparation of tofacitinib, an intermediate used in the process, i.e., isopropanol solvate of methyl ((3R,4R)-1-benzyl-4-methylpiperidin-3-yl)carbamate dibenzoyl-L-tartrate, an intermediate, having excellent stability, useful for the preparation of tofacitinib, i.e., (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine acetate, and a process for preparing tofacitinib or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to new anti-hCD3 antibodies that, in contrast to prior art anti-CD3 antibodies, bind specifically to human CD3 at acidic pH, but do not significantly bind to human CD3 at neutral or physiological pH, methods to produce these antibodies and therapeutic uses of these antibodies. These antibodies are able to activate T cells at acidic pH while having significantly reduced activity at neutral or physiological pH.

Abstract: The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.

Abstract: A semiconductor device includes a memory string connected between a source line and a bit line. The memory string includes first memory cells stacked along a first channel layer, second memory cells stacked along a second channel layer, and at least one switching memory cell connected between the first memory cells and the second memory cells. A method for operating the semiconductor device includes programming a selected first memory cell among the first memory cells, selecting a second memory cell to be programmed among the second memory cells, applying a program voltage to a word line connected to the selected second memory cell, turning off the switching memory cell such that the first channel layer and the second channel layer are electrically isolated from each other, and applying a pass voltage to word lines connected to unselected memory cells among the first and second memory cells.

Abstract: Provided are a novel process for preparing a diaminopyrimidine derivative or acid addition salt thereof having an activity as a 5-HT4 receptor agonist, crystalline forms of a hydrochloride of the diaminopyrimidine derivative, and processes for preparing the same.

Abstract: A method for operating a memory device includes providing a memory block including at least one source select transistor coupled between a source line and a bit line, a plurality of memory cells, and a drain select transistor, controlling a source select line coupled to the at least one source select transistor and a plurality of word lines coupled to the plurality of memory cells to be in a floating state, and applying an erase voltage to the source line and the bit line.

Abstract: The present invention provides intermediates useful for the synthesis of an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors; and processes for preparing the same. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.

Abstract: A memory device includes a memory cell array including a plurality of strings, a peripheral circuit coupled to the memory cell array and configured for sequentially performing a program voltage apply operation, a program verify operation, and a hole injection operation on the plurality of strings, and a control logic configured for controlling an operation of the peripheral circuit, wherein the control logic controls the operation of peripheral circuit to generate Gate Induced Drain Leakage (GIDL) at a channel under a select transistor of each of the plurality of strings during the hole injection operation.

Abstract: A memory device includes a memory cell array having a plurality of memory blocks sharing a source line, a peripheral circuit for performing a program operation and an erase operation on a selected memory block among the plurality of memory blocks, and a control logic for controlling the peripheral circuit. The control logic controls the peripheral circuit such that some source select transistors adjacent to the source line among a plurality of source select transistors included in an unselected memory block among the plurality of memory blocks are floated in a source line precharge operation during the program operation.

Abstract: The present invention provides a novel process for preparing an aminopyrimidine derivative or pharmaceutically acceptable salt thereof having a selective inhibitory activity against protein kinases, especially against the protein kinases for mutant epidermal growth factor receptors. And also, the present invention provides novel intermediates useful for said process and processes for preparing the same.