Patent number: 6133241
Abstract: A method for increasing the plasma high density lipoprotein(HDL) level in a mammal comprises administering a bioflavonoid of formula(I) or plant extract containing same thereto: ##STR1## wherein, R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5.sub.7 R.sup.6, R.sup.7, R.sup.8 and R.sup.9 are each independently hydrogen; a hydroxy group; a C.sub.1-9 alkoxy group optionally substituted with one or more substituents selected from the group consisting of a hydroxy, C.sub.1-5 alkoxy, aryloxy, and phenyl group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C.sub.5-9 cycloalkyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C.sub.5-9 cycloalkylcarbonyloxy group substituted with 1 to 3 substituents selected from the group consisting of a hydroxy, alkoxy, aryloxy, halogen, nitro and amido group; a C.sub.2-10 or C.sub.
Type:
Grant
Filed:
October 22, 1998
Date of Patent:
October 17, 2000
Assignee:
Korea Institute of Science & Technology
Inventors:
Song-Hae Bok, Tae-Sook Jeong, Surk-Sik Moon, Yong-Kook Kwon, Byung-Hwa Hyun, Chul-Ho Lee, Yang-Kyu Choi, Myung-Sook Choi, Sung-Gyu Kim, Og-Sung Moon, Sae-Bom Lee, Eun-Sook Lee, Byung-Tae Ahn