Abstract: The present invention relates to a composition containing Horse chestnut extract that inhibits angiogenesis and matrix metalloproteinase activity. The Horse chestnut extract of the present invention inhibits angiogenesis and activity of matrix metalloproteinase, so that it can be applied to treat and prevent disease related to angiogenesis and/or matrix metalloproteinase.

Abstract: The present invention provides an MMP-inhibitory composition comprising chalcone or its derivatives. They inhibit the MMPs in collagenase subfamily as well as those in gelatinase subfamily. The MMP inhibitory activity of chalcone derivatives was similar to or greater than that of parent compound, chalcone. Chalcone or its derivatives of the present invention inhibit activity of matrix metalloproteinase, so that it can be applied to treat and prevent diseases related to matrix metalloproteinase.

Abstract: The present invention relates to a composition containing ginkgo biloba extract that inhibit angiogenesis and matrix metalloproteinases. The ginkgo biloba extract of the present invention suppress angiogenesis and activity of matrix metalloproteinases, so that it can be applied to medicine for disease related in angiogenesis and matrix metalloproteinases.

Abstract: The present invention relates to a pharmaceutical composition for inhibiting angiogenesis which comprises arginine deiminase as an active ingredient, where the arginine deiminase, obtained from Mycoplasma arginini or prepared by a genetic recombination technique, may be conjugated to an activated polymer to lower its immunogenecity and increase its life time. The pharmaceutical composition of the present invention exhibits an excellent inhibitory activity against angiogenesis.

Abstract: The present invention relates to a composition comprising Melissa leaf extract that inhibits angiogenesis and matrix metalloproteinase activity. The Melissa leaf extract of the present invention inhibits angiogenesis and activity of matrix metalloproteinase, so that it can be applied to treat or prevent diseases related to angiogenesis and matrix metalloproteinase. The composition of the present invention comprising Melissa leaf extract may also comprise more than one component of the other anti-angiogenic, anti-cancer, anti-inflammatory and anti-aging components. This particular composition comprising Melissa leaf extract can be used for pharmaceutical, dietetic and/or cosmetic purposes.

Abstract: A composition comprising ticlopidine and a Ginkgo biloba extract is used in the manufacture of a medicine for inhibiting angiogenesis, which has an enhanced anti-angiogenic activity with reduced side effect.

Abstract: A warning device for use on a vehicle for sensing an approaching object when the vehicle is moving backward. The device produces a first signal when the object is in remote proximity of the vehicle and at least a second signal when the object is in close proximity of the vehicle. The device has a circuit for emitting intermittent infrared light when the vehicle is moving backward and a circuit for receiving the infrared light reflected from the object. The circuit for receiving produces a receive signal indicative of the received infrared light. The device further has an output of the circuit for receiving connected to two inverting inputs of both first and second differential amplifiers, inverting inputs of the first and second differential amplifiers being connected by a first and second variable resistors, respectively, to an applied voltage. First and second outputs of the first and second differential amplifiers, respectively, are connected to first and second inputs of an AND gate.