Abstract: The present invention relates to a compound represented by Formula 1, a pharmaceutically acceptable salt thereof, or an isomer thereof, and a pharmaceutical composition for treating or preventing proteasome-mediated diseases, comprising the same as an active ingredient.

Abstract: Disclosed is a method for producing calcobutrol used as an MRI contrast agent. The method comprises the steps of: obtaining butrol represented by chemical formula 2 in the specification by reacting a gadobutrol represented by chemical formula 1 in the specification and a decomplexing agent; and obtaining a calcobutrol represented by chemical Formula 3 in the specification by reacting butrol with calcium ions.

Abstract: Disclosed are: an intermediate capable of high-purity synthesis of gadobutrol which can be used as an MRI contrast agent; and a gadobutrol production method using same. The gadobutrol intermediate is represented by Chemical Formula 2 in the specification.

Abstract: Disclosed is a method for producing 1-palmitoyl-2-linoleoyl-3-acetyl glycerol of high purity with high yield by carrying out acetylation of 1-palmitoyl glycerol with acetic anhydride or a mixture of acetic anhydride and acetyl chloride. The method for producing 1-palmitoyl-2-linoleoyl-3-acetyl glycerol comprises the steps of: preparing 1-palmitoyl-3-acetyl glycerol intermediate of Chemical formula 2 in the specification by reacting 1-palmitoyl glycerol of Chemical formula 1 in the specification and an acetylating agent selected from the group consisting of (i) acetic anhydride and (ii) a mixture of acetic anhydride and acetyl chloride; and reacting the 1-palmitoyl-3-acetyl glycerol intermediate and linoleic acid.

Abstract: Disclosed is a method for producing calcobutrol used as an MRI contrast agent. The method comprises the steps of: obtaining butrol represented by chemical formula 2 in the specification by reacting a gadobutrol represented by chemical formula 1 in the specification and a decomplexing agent; and obtaining a calcobutrol represented by chemical Formula 3 in the specification by reacting butrol with calcium ions.

Abstract: Disclosed are: an intermediate capable of high-purity synthesis of gadobutrol which can be used as an MRI contrast agent; and a gadobutrol production method using same. The gadobutrol intermediate is represented by Chemical Formula 2 in the specification.

Abstract: Provided is a dispenser mapping apparatus for multi-analysis and an operation method thereof according to an embodiment. The method may include receiving analysis information—the analysis information including information relating to at least one of a plurality of samples, a detection gene for each of the plurality of samples, and a primer corresponding to the detection gene which are subject to analysis—dividing a reaction plate into a plurality of areas and sequentially arranging the plurality of samples and the plurality of primers on the plurality of areas of the reaction plate.

Abstract: Systems, devices, and methods for the automated production of fermented beverages are provided. The device may be modular, portable and/or self-cleaning. The device includes a housing with chambers that receive a removable fermentation vessel with yeasts and ingredients capable of undergoing fermentation. Flavoring agents and other ingredients may also be added to produce beer, wine, or other alcoholic libations of profound character and freshness. The device includes a controller that initiates fermentation, senses the fermentation status and automatically controls fermentation parameters based on a desired fermentation profile. The controller automatically directs parameters such as carbonation, conditioning, aging, and chilling according to a programmed recipe or consumer preference to create an enjoyable customized beverage.

Abstract: An electron gun for a color CRT includes a main focusing lens unit that focuses the electron beams generated by a triode unit. The main focusing lens unit includes a first and a second electrostatic screen grid having three electron beam through holes linearly-arranged for passing three electron beams, two of the holes being external and an oval shaped hole that passes all three electron beams. The oval shaped holes being spaced a distance, d1 and d2, respectively, from the through holes. Furthermore, the first grid external holes have an external distance HL1 and an internal distance HR1 and the second grid external holes have an external distance HL2 and an internal distance HR2; and wherein HL1 is greater than HR1, HL2 is greater than HR2, d1 is greater than d2, HL2 is greater than HL1, and HL2+HR2 is greater than HL1+HR1.

Abstract: In an color CRT, an electron gun for the color CRT includes a triode unit for generating three electron beams and controlling and accelerating the generated electron beams; a main focusing lens unit that focuses the electron beams generated by the triode unit; a first electrostatic screen grid installed in the main focusing lens unit having three electron beam through holes linearly-arranged for passing the three electron beams and two of the holes are external holes, and the first grid having a first oval shaped hole that passes all three electron beams, the first oval shaped hole spaced a distance d1 from the through holes; and a second electrostatic screen grid installed in the main focusing lens unit having three electron beam through holes linearly-arranged for passing the three electron beams and two of the holes are external holes, and the second grid having a second oval shaped hole that passes all three electron beams, the second oval shaped hole spaced a distance d2 from the through holes; wherein t

Abstract: The invention provides a degaussing circuit using a relay having the circuit for the TV of a remote controller type including the standby-power taking-out device to drive a MICOM, the degaussing device using the applied ac power and the drive-power taking-out device to drive a TV, the device including; a control device to control said degaussing device, the drive-power taking-out device, and the standby-power taking-out device through the relay and to drive the TV, located among the output stage of the standby-power taking-out device, the input stage of the degaussing device, and the input stage of the drive-power taking out device. Obtaining the cleaner screen may be attained according to the present invention.