Abstract: A plurality of methods of analysis of images of eyes of a subject taken by a reflex photometer are disclosed. In this methods, a computer coupled to the reflex photometer is programmed to locate the pupil of at at least one eye, crop an image array containing the pupil from the total image and perform analyses on the cropped array to determine whether conditions are present indicative of disease processes in the eye. In essence, parameters of the subject eye are developed, and these subject pararmeters are compared to the same parameters developed by a normal eye. In addition, indications of strabismus are examined by comparing the area of the white portion of the eye on one side of the iris with the white portion on the other side of the iris.