Abstract: Provided are bimodal medium density polyethylene compositions, and microirrigation drip tapes including the same. The bimodal medium density polyethylene compositions can be extruded at high lines speed while maintaining other desirable properties. The bimodal medium density polyethylene compositions include a high molecular weight (HMW) polyethylene component and a low molecular weight (LMW) polyethylene component. The bimodal medium density polyethylene composition has a density of from 0.937 to 0.946 g/cm3; a high load melt index (I21) from 7 to 20 g/10 min; a crossover G?=G? of from 30 to 50 kPa; a notched constant tensile load failure time at 30% yield stress, as measured according to ASTMD5397, of greater than 700 hours; and a strain hardening modulus of greater than 65 MPa.

Abstract: An activity timing and scoring system disclosed herein is based on a tightly timed/synchronized data structure that allows for concurrent and accurate collection and distribution of scoring and timing data. The techniques described herein use a precision clock communicated to participating end points using the Precision Time Protocol (PTP) and/or other known or unique time correction algorithms to make one or more system clocks more uniform and to relate one or more game times with a global time.

Abstract: Products, such as devices, prostheses, and materials, whose surfaces have been modified in order to impart beneficial properties to these products are disclosed. The surface-modified products have improved biocompatibility compared to a corresponding product that lacks the modification. Following implantation in a subject, the surface-modified products induce a lower foreign-body response, compared to a corresponding unmodified product.

Abstract: The present disclosure generally relates to updating user interfaces based on user presence and/or outputting information about detected real-world object.

Abstract: Articles are described comprising a first substrate and a second substrate. At least one adhesive layer is disposed between the first and second substrates. The article further comprises a multilayer film within at least a portion of the adhesive layer(s). Also described is a method of disassembly comprising providing an adhesively bonded article as described herein; and separating the first substrate from the second substrate by delaminating the (e.g. multilayer) film. In other embodiments, adhesive articles (e.g. tape) are described comprising a (e.g. multilayer) film and methods of making adhesively bonded articles that comprise a (e.g. multilayer) film. Also described are methods of reworking, repairing, repurposing, or recycling an article, and articles.

Abstract: Provided are bimodal medium density polyethylene compositions, and microirrigation drip tapes including the same. The bimodal medium density polyethylene compositions can be extruded at higher lines speed while maintaining other desirable properties. The bimodal medium density polyethylene compositions include a high molecular weight (HMW) polyethylene component and a low molecular weight (LMW) polyethylene component. In some embodiments, the bimodal medium density polyethylene composition has a density of from 0.937 to 0.949 g/cm3; a high load melt index (I21) from 12 to 30 g/10 min: a crossover G?=G? of from 30 to 45 kPa; and a calculated LMW density of the LWM polyethylene component of less than or equal to 0.974 g/cm3.

Abstract: The beverage brewing device, which is configured for use with a beverage brewer having an inlet probe for dispensing water and an outlet probe, includes a body defining a brew chamber configured to contain a dry beverage medium and at least one outlet probe receptacle extending upwardly from a bottom surface of the body. The outlet probe receptacle is sized and configured to receive an outlet probe of a beverage brewer. A lid is removably securable to the body and is engageable with the body to selectively enclose a top opening of the body. An inlet probe opening is defined in the lid for receiving an inlet probe of the beverage brewer. At least one filter is defined within in the body, wherein the filter is configured to retain a dry beverage medium within the brew chamber while allowing a brewed beverage to pass through the brew chamber.

Abstract: Audio qualities of a call and of a call recording are identified and compared to authenticate the call recording as a true representation of the call. A call is enabled between two or more participants, and the call is recorded to generate a call recording. The call recording is authenticated based on a match between audio watermarks included within the call and audio watermarks included within the call recording. An indication of the authentication is then output, such as for further processing or display.

Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.

Abstract: A content recommendation system includes a computing platform having a hardware processor and a system memory storing a content surfacing software code providing a user interface. The hardware processor executes the content surfacing software code to receive an initiation signal identifying a user, and, in response, identify content items as desirable content items to the user based on the user and metadata describing each of the desirable content items. In addition, the content surfacing software code generates a networked map of nodes corresponding respectively to the desirable content items, where the distances between nodes are based on the similarity of the metadata describing the desirable content items corresponding to the nodes. The content surfacing software code further outputs the networked map for display to the user via the user interface, the nodes being displayed as thumbnail images depicting the desirable content and selectable by the user.

Abstract: Dysfunctional or exhausted T cells arise in chronic diseases including chronic viral infections and cancer, and express high levels of co-inhibitory receptors. Therapeutic blockade of these receptors has clinical efficacy in the treatment of cancer. While co-inhibitory receptors are co-expressed, the triggers that induce them and the transcriptional regulators that drive their co-expression have not been identified. The immunoregulatory cytokine IL-27 induces a gene module in T cells that includes several known co-inhibitory receptors (Tim-3, Lag-3, and TIGIT). The present invention provides a novel immunoregulatory network as well as novel cell surface molecules that have an inhibitory function in the tumor microenvironment. The present invention further provides the novel discovery that the transcription factors Prdm1 and c-Maf cooperatively regulate the expression of the co-inhibitory receptor module.

Abstract: Systems and methods are disclosed that allow for providing targeted asset/advertisements for broadcast-wide programming feeds. The systems and methods allow network platforms to select among asset options provided with a content stream and/or replace assets in the content stream. In one arrangement, after selecting an asset, the asset is inserted into the content stream and the content stream is disseminated to subsequent network platforms (e.g., local platforms). At this time, the local platforms may insert local assets into the content stream in predetermined local asset insertion spots.

Abstract: A burner assembly including a body, the body including a first aperture, a second aperture, a cavity between the first and second aperture, and a gas inlet in fluid communication with the cavity. The assembly also includes a gas nozzle arranged to terminate a first distance from the first aperture of the body. The assembly also includes a fuel tube and a fuel nozzle disposed within the cavity of the body, the fuel tube arranged to terminate within a first through-bore of the gas nozzle, and the fuel nozzle being removably secured to the fuel tube, the fuel nozzle terminating a second distance from the first aperture of the body, wherein the first distance is less than the second distance or the first distance is substantially equal to the second distance.

Abstract: A tool, such as a tape measure, including a spring-based retraction system is shown. Various spring-based retraction system embodiments are configured to decrease the size occupied by the spring within the tape measure housing, which consequently reduces tape measure housing size providing a more compact tape measure. Various spring-based retraction system embodiments are configured to control retraction of the tape measure in a manner that reduces whip or otherwise controls tape blade retraction. Some retraction system embodiments utilize a reduction gear train, and others utilize a compression spring and a transmission system that converts rotational movement of the tape reel to axial movement, which compresses the spring.

Abstract: A method of picking a predetermined number of fasteners is provided. The method includes placing a fastener handling tool adjacent the predetermined number of fasteners. The fastener handling tool includes a body that includes a holding side, a picking side opposite the holding side, a front wall, a rear wall opposite the front wall and opposite side walls that extend between the holding side and the picking side. The body includes an elongated slot on the picking side that extends between the opposite side walls along a width of the body and an elongated hole on the picking side that is offset from the elongated slot. The elongated slot and the elongated hole extend parallel between the opposite sidewalls providing a gap between the elongated slot and the elongated hole. A magnet is located at the elongated hole. The predetermined number of fasteners are attracted to an edge of the elongated slot using the magnet located at the elongated hole.

Abstract: Assets of broadcast network content are targeted to network users of interest based on location information regarding user equipment devices. Asset providers can specify location targeting criteria via a graphical user interface displaying mapping information. This location targeting criteria can then be compared to location information regarding user equipment devices so that assets are delivered to appropriate devices. The comparison of the location targeting criteria to the device location information can be performed at the user equipment devices or at another location. In the latter case, the assets can be addressed to appropriate user equipment devices or appropriate user equipment devices can be directed to select the asset, which is broadcast via the network. In this manner, assets can be targeted to individual network users on a basis independent of network topology.

Abstract: A voice-controlled electronic device that includes a device housing having a longitudinal axis bisecting opposing top and bottom surfaces and a side surface extending between the top and bottom surfaces. The device can further include one or more microphones disposed within the device housing and distributed radially around the longitudinal axis; a processor configured to execute computer instructions stored in a computer-readable memory for interacting with a user and processing voice commands received by the one or more microphones and first transducer and second transducers configured to generate sound waves within different frequency ranges.

Abstract: The Internet can be configured to provide communications to a large number of Internet-of-Things (IoT) devices. Devices can be designed to address the need for network layers, from central servers, through gateways, down to edge devices, to grow unhindered, to discover and make accessible connected resources, and to support the ability to hide and compartmentalize connected resources. Network protocols can be part of the fabric supporting human accessible services that operate regardless of location, time, or space. Innovations can include service delivery and associated infrastructure, such as hardware and software. Services may be provided in accordance with specified Quality of Service (QoS) terms. The use of IoT devices and networks can be included in a heterogeneous network of connectivity including wired and wireless technologies.

Abstract: Provided is 5-(3-chloro-4-fluorophenyl)-7-cyclopropyl-3-(2-(3-fluoro-3-methylazetidin-1-yl)-2-oxoethyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one and pharmaceutically acceptable salts thereof, and their uses in the treatment of psychiatric, neurological, and neurodevelopmental disorders, as well as diseases of the nervous system.