Patents by Inventor C. Chiou

C. Chiou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230130038
    Abstract: High-yield mammalian transient expression systems can include a cell culture media (particularly serum free, non-animal derived, and/or chemically defined media) for introducing macromolecules and compounds (e.g., nucleic acid molecules) into cells (e.g., eukaryotic cells). Cells containing such introduced materials can then be cultured in the cell culture media. In particular, the invention allows introduction of nucleic acid molecules (e.g., vectors) into cells (particularly mammalian cells) and expression of proteins encoded by the nucleic acid molecules in the cells. The invention obviates the need to change the cell culture medium each time a different procedure is performed with the cells (e.g., culturing cells vs. transfecting cells). The invention also relates to compositions and kits useful for culturing and transforming/transfecting cells.
    Type: Application
    Filed: October 31, 2022
    Publication date: April 27, 2023
    Inventors: Sanjay K. VASU, Chao Yan LIU, Jeffrey ROGERS, Maria Isabel CISNEROS, Jingqui LI, Henry C. CHIOU, Meredith Bauman JONES
  • Publication number: 20210129098
    Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.
    Type: Application
    Filed: January 15, 2021
    Publication date: May 6, 2021
    Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
  • Patent number: 10919011
    Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.
    Type: Grant
    Filed: October 19, 2018
    Date of Patent: February 16, 2021
    Assignee: Adamis Pharmaceuticals Corporation
    Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
  • Publication number: 20190255265
    Abstract: Dry powder inhalers and dry powder inhaler storage cassettes including a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance, the compartment being configured such that said preloaded doses are sealed within said compartment and such that the carrier may be advanced from the compartment to the chamber through an exit provided with a moisture barrier sealing system, wherein the moisture barrier sealing system is configured and arranged such that it is relaxable during advancement of the carrier, said sealing system being in sealing configuration prior to an advancement of the carrier, relaxed upon an advancement of the carrier and returned to its sealing configuration at the latest after release of the powder associated with said area of the carrier.
    Type: Application
    Filed: April 30, 2019
    Publication date: August 22, 2019
    Inventors: Peter D. Hodson, Stephen W. Stein, Herbert C. Chiou, Zhaolin Wang, Thomas S. Robison, Michael K. Domroese, Blake D. Walburg
  • Patent number: 10376662
    Abstract: The disclosure describes powder inhalers and dry powder inhaler storage cassettes that include a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance. The compartment is configured such that the preloaded doses are sealed within the compartment and such that the carrier may be advanced from the compartment to the chamber through an exit provided with a moisture barrier sealing system. The moisture barrier sealing system is configured and arranged such that it is relaxable during advancement of the carrier. The sealing system is in sealing configuration prior to an advancement of the carrier, is relaxed upon an advancement of the carrier and is returned to its sealing configuration at the latest after release of the powder associated with the area of the carrier.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: August 13, 2019
    Assignee: Adamis Pharmaceuticals Corporation
    Inventors: Peter D. Hodson, Stephen W. Stein, Herbert C. Chiou, Zhaolin Wang, Thomas S. Robison, Michael K. Domroese, Blake D. Walburg
  • Patent number: 10307507
    Abstract: Hydrocolloid compositions, wound dressings, methods of using such compositions and such wound dressings, and methods of forming such hydrocolloid compositions, wherein the hydrocolloid compositions include a hydrophobic, unsaturated, elastomeric polymer; a hydrocolloid absorbent; and a hydrophilic polymer including an unsaturated polymer backbone having polyalkylene ether groups bonded thereto.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: June 4, 2019
    Assignee: 3M Innovative Properties Company
    Inventors: Herbert C. Chiou, Hae-Seung Lee
  • Publication number: 20190054435
    Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.
    Type: Application
    Filed: October 19, 2018
    Publication date: February 21, 2019
    Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
  • Patent number: 10188996
    Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: January 29, 2019
    Assignee: Adamis Pharmaceuticals Corporation
    Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
  • Publication number: 20170095782
    Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.
    Type: Application
    Filed: October 2, 2015
    Publication date: April 6, 2017
    Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
  • Publication number: 20170080169
    Abstract: Dry powder inhalers and dry powder inhaler storage cassettes including a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance, the compartment being configured such that said preloaded doses are sealed within said compartment and such that the carrier may be advanced from the compartment to the chamber through an exit provided with a moisture barrier sealing system, wherein the moisture barrier sealing system is configured and arranged such that it is relaxable during advancement of the carrier, said sealing system being in sealing configuration prior to an advancement of the carrier, relaxed upon an advancement of the carrier and returned to its sealing configuration at the latest after release of the powder associated with said area of the carrier.
    Type: Application
    Filed: September 26, 2016
    Publication date: March 23, 2017
    Inventors: Peter D. Hodson, Stephen W. Stein, Herbert C. Chiou, Zhaolin Wang, Thomas S. Robison, Michael K. Domroese, Blake D. Walburg
  • Patent number: 9474870
    Abstract: The disclosure describes powder inhalers and dry powder inhaler storage cassettes that include a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance. The compartment is configured such that the preloaded doses are sealed within the compartment and such that the carrier may be advanced from the compartment to the chamber through an exit provided with a moisture barrier sealing system. The moisture barrier sealing system is configured and arranged such that it is relaxable during advancement of the carrier. The sealing system is in sealing configuration prior to an advancement of the carrier, is relaxed upon an advancement of the carrier and is returned to its sealing configuration at the latest after release of the powder associated with the area of the carrier.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: October 25, 2016
    Assignee: Adamis Pharmaceuticals Corporation
    Inventors: Peter D. Hodson, Stephen W. Stein, Herbert C. Chiou, Zhaolin Wang, Thomas S. Robison, Michael K. Domroese, Blake D. Walburg
  • Publication number: 20160074552
    Abstract: A discontinuous hydrocolloid article is disclosed that provides for a high rate of water absorption and a high rate of water vapor transmission. Also, disclosed is a method of making a discontinuous hydrocolloid article. In one embodiment, the discontinuous hydrocolloid article comprises a plurality of cross-linked polymer strands comprising a hydrophobic polymer and a hydrocolloid dispersed throughout the hydrophobic polymer and a plurality of joining strands. Each polymer strand repeatedly contacts an adjacent joining strand at bond regions.
    Type: Application
    Filed: April 28, 2014
    Publication date: March 17, 2016
    Inventors: JUNKANG J. LIU, WEI ZHANG, HERBERT C. CHIOU, BRUCE D. KLUGE, GREGORY J. ANDERSON
  • Publication number: 20160015851
    Abstract: Hydrocolloid compositions, wound dressings, methods of using such compositions and such wound dressings, and methods of forming such hydrocolloid compositions, wherein the hydrocolloid compositions include a hydrophobic, unsaturated, elastomeric polymer; a hydrocolloid absorbent; and a hydrophilic polymer including an unsaturated polymer backbone having polyalkylene ether groups bonded thereto.
    Type: Application
    Filed: March 11, 2014
    Publication date: January 21, 2016
    Applicant: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Herbert C. Chiou, Hae-Seung Lee
  • Publication number: 20150217065
    Abstract: Dry powder inhalers and dry powder inhaler storage cassettes including a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance, the compartment being configured such that said preloaded doses are sealed within said compartment and such that the carrier may be advanced from the compartment to the chamber through an exit provided with a moisture barrier sealing system, wherein the moisture barrier sealing system is configured and arranged such that it is relaxable during advancement of the carrier, said sealing system being in sealing configuration prior to an advancement of the carrier, relaxed upon an advancement of the carrier and returned to its sealing configuration at the latest after release of the powder associated with said area of the carrier.
    Type: Application
    Filed: February 13, 2015
    Publication date: August 6, 2015
    Inventors: Peter D. Hodson, Stephen W. Stein, Herbert C. Chiou, Zhaolin Wang, Thomas S. Robison, Michael K. Domroese, Blake D. Walburg
  • Patent number: 8985102
    Abstract: Dry powder inhalers and dry powder inhaler storage cassettes including a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: March 24, 2015
    Assignee: Adamis Pharmaceuticals Corporation
    Inventors: Peter D. Hodson, Stephen W. Stein, Herbert C. Chiou, Zhaolin Wang, Thomas S. Robison, Michael K. Domroese, Blake D. Walburg
  • Patent number: 8318741
    Abstract: The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision.
    Type: Grant
    Filed: April 5, 2012
    Date of Patent: November 27, 2012
    Assignee: The Texas A & M University System
    Inventor: George C. Chiou
  • Publication number: 20120196868
    Abstract: The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision.
    Type: Application
    Filed: April 5, 2012
    Publication date: August 2, 2012
    Applicant: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventor: GEORGE C. CHIOU
  • Publication number: 20120132203
    Abstract: Dry powder inhalers and dry powder inhaler storage cassettes including a compartment housing an elongate carrier preloaded with a plurality of doses of finely divided powder comprising a biologically active substance, the compartment being configured such that said preloaded doses are sealed within said compartment and such that the carrier may be advanced from the compartment to the chamber through an exit provided with a moisture barrier sealing system, wherein the moisture barrier sealing system is configured and arranged such that it is relaxable during advancement of the carrier, said sealing system being in sealing configuration prior to an advancement of the carrier, relaxed upon an advancement of the carrier and returned to its sealing configuration at the latest after release of the powder associated with said area of the carrier.
    Type: Application
    Filed: May 18, 2010
    Publication date: May 31, 2012
    Inventors: Peter D. Hodson, Stephen W. Stein, Herbert C. Chiou, Zhaolin Wang, Thomas S. Robison, Michael K. Domroese, Blake D. Walburg
  • Publication number: 20120115959
    Abstract: The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision. The present invention includes compositions and methods that provide protection in a patient suffering from an eye disease such as age-related macular degeneration. In certain embodiments, the compositions of the present invention are administered during degeneration, and the composition includes an effective amount of an agent that increases choroidal blood flow.
    Type: Application
    Filed: November 23, 2011
    Publication date: May 10, 2012
    Inventor: George C. Chiou
  • Publication number: 20120071485
    Abstract: The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision.
    Type: Application
    Filed: November 23, 2011
    Publication date: March 22, 2012
    Inventor: George C. Chiou