Abstract: The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Abstract: The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Abstract: A method is described for shearing a tissue wall between a first cavity and an adjacent second cavity in a human or animal body. The tissue wall has a periphery forming an edge of an opening between the first cavity and the second cavity. A first member is placed into the first cavity, such that the first member is adjacent the wall. A second member is placed in the second cavity, proximate the first member. The first and second members have materials which magnetically attract one another. The first member and the second member are placed such that there is magnetic attraction between the first member and the second member through the wall and thereby compress an overlapping portion of the wall to create pressure necrosis. The first member and the second member are connected by a thread, wherein the thread extends over the edge of the opening.

Abstract: A device for shearing tissue in a human or animal body may include a first member made of a first material and a second member made of a second material. A thread is connected to the first member and to the second member, and the first and second materials show magnetic attraction between one another. A means is provided for pulling the thread between the first and second members.

Abstract: An assembly for delivering a therapeutic agent includes a catheter and a supply system. The catheter includes a catheter body having a first lumen extending from a proximal end to a distal end and defining a longitudinal axis, and a first outlet adjacent to the distal end and in fluid communication with the first lumen. The supply system includes an inlet port for a carrier fluid, an inlet port for the agent, and an output port in fluid communication with the two inlet ports and the first lumen at the proximal end. The supply system further includes a fluid path from one inlet port to the output port having a constriction in vicinity of the other inlet port configured to aspirate the agent by Venturi effect. The catheter includes a valve arranged adjacent the one outlet and in fluid communication with the first lumen.

Abstract: This disclosure relates generally to medical devices, systems, and methods for locating devices and/or anatomy during medical procedures. More particularly, in some embodiments, the disclosure relates to medical device and/or anatomy locating devices, access devices, and systems and methods thereof, for use during, e.g., gastrojejunostomy procedures. In an aspect, a medical device locator may include an elongate member (such as sheath or guidewire) having a proximal end, a distal end, a longitudinal axis, and a length extending along the longitudinal axis. A location device may be disposed along the length of the elongate member.

Abstract: The present disclosure relates generally to stents, systems, and methods for gastrointestinal treatment. In some embodiments, a stent may include a tubular scaffold having a first end opposite a second end, wherein a lumen extends between the first and second ends. The tubular scaffold may include a flared section and a medial section extending from the flared section, wherein a first diameter of the flared section is greater than a second diameter of the medial section. The stent may further include a liner extending partially along a surface of the tubular scaffold, wherein the liner is spaced from an anchoring region of the flared section to promote tissue ingrowth with the flared section.

Abstract: A device for shearing tissue in a human or animal body may include a first member made of a first material and a second member made of a second material. A thread is connected to the first member and to the second member, and the first and second materials show magnetic attraction between one another. A means is provided for pulling the thread between the first and second members.