Patents by Inventor C. Fathman

C. Fathman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and composition for inhibiting cardiovascular cell proliferation
    Publication number: 20100113353
    Abstract: Cardiovascular cell proliferation in a blood vessel subjected to trauma, such as angioplasty, vascular graft, anastomosis, or organ transplant, can be inhibited by contacting the vessel with a polymer consisting of from 6 to about 30 amino acid subunits, where at least 50% of the subunits are arginine, and the polymer contains at least six contiguous arginine subunits. Exemplary polymers for this purpose include arginine homopolymers 7 to 15 subunits in length.
    Type: Application
    Filed: September 8, 2009
    Publication date: May 6, 2010
    Applicant: Leland Stanford Junior University
    Inventors: John P. Cooke, Garrison C. Fathman, Jonathan B. Rothbard, Shiro Uemura, Robert C. Robbins, Murray H. Kown
  • Compositions and Methods for Treating Diseases
    Publication number: 20070185203
    Abstract: This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and wound healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
    Type: Application
    Filed: April 18, 2007
    Publication date: August 9, 2007
    Inventors: Jonathan Rothbard, Paul McGrane, Edgar Engleman, C. Fathman, Erik Kreider
  • Compositions and methods for treating diseases
    Publication number: 20050192210
    Abstract: This invention relates to compositions and methods for treatment of vascular conditions. The invention provides arginine polymers and arginine homopolymers for the treatment and/or prevention of glaucoma, pulmonary hypertension, asthma, chronic obstructive pulmonary disease, erectile dysfunction, Raynaud's syndrome, heparin overdose, vulvodynia, and wound healing. The invention also provides arginine polymers and arginine homopolymers for use in organ perfusate and preservation solutions.
    Type: Application
    Filed: March 1, 2005
    Publication date: September 1, 2005
    Inventors: Jonathan Rothbard, Paul McGrane, Edgar Engleman, C. Fathman, Erik Kreider
  • Method and composition for inhibiting cardiovascular cell proliferation
    Publication number: 20040074504
    Abstract: Cardiovascular cell proliferation in a blood vessel subjected to trauma, such as angioplasty, vascular graft, anastomosis, or organ transplant, can be inhibited by contacting the vessel with a polymer consisting of from 6 to about 30 amino acid subunits, where at least 50% of the subunits are arginine, and the polymer contains at least six contiguous arginine subunits. Exemplary polymers for this purpose include arginine homopolymers 7 to 15 subunits in length.
    Type: Application
    Filed: May 20, 2003
    Publication date: April 22, 2004
    Inventors: John P. Cooke, Garrison C. Fathman, Jonathan B. Rothbard, Shiro Uemura, Robert C. Robbins, Murray H. Kown
  • Method and composition for inhibiting cardiovascular cell proliferation
    Patent number: 6605115
    Abstract: Cardiovascular cell proliferation in a blood vessel subjected to trauma, such as angioplasty, vascular graft, anastomosis, or organ transplant, can be inhibited by contacting the vessel with a polymer consisting of from 6 to about 30 amino acid subunits, where at least 50% of the subunits are arginine, and the polymer contains at least six contiguous arginine subunits. Exemplary polymers for this purpose include arginine homopolymers 7 to 15 subunits in length.
    Type: Grant
    Filed: June 5, 2000
    Date of Patent: August 12, 2003
    Assignee: Board of Trustees of the Leland Stanford Junior University
    Inventors: John P. Cooke, Garrison C. Fathman, Jonathan B. Rothbard, Shiro Uemura, Robert C. Robbins, Murray H. Kown