Patents by Inventor C. Gordon Todderud

C. Gordon Todderud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human phosphatase RET31, and variants thereof
    Patent number: 7358074
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: June 2, 2005
    Date of Patent: April 15, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Donald G. Jackson, Chandra S. Ramanathan, Liana Lee, Nathan Siemers, Suzanne J. Suchard, Joshua Finger, C. Gordon Todderud, Dana Banas
  • Identification and cloning of a novel human gene, RET16, involved in the intracellular signaling cascade
    Patent number: 7198911
    Abstract: The present invention describes a newly discovered polynucleotide encoding a protein involved in the cell signaling cascade, called RET16, cloned, isolated and identified from TNF-alpha stimulated human microvascular endothelial cells, as well as mouse and rat RET16 orthologs thereof. Also described are the RET16 polypeptide sequence, expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Methods for screening for modulators, particularly inhibitors, of the human RET16 protein, and use of the RET16 polynucleotide and polypeptide for therapeutics and diagnostics are described.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: April 3, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: C. Gordon Todderud, Joshua Finger, Jill Rillema
  • Polynucleotides encoding the novel human phosphatase, RET31, and variants thereof
    Patent number: 7153678
    Abstract: The present invention provides novel polynucleotides encoding human phosphatase polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel human phosphatase polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides, particularly cardiovascular diseases and/or disorders. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
    Type: Grant
    Filed: December 20, 2001
    Date of Patent: December 26, 2006
    Assignee: Bristol-Myers Squibb
    Inventors: Donald G. Jackson, Chandra S. Ramanathan, John N. Feder, Liana Lee, Thomas C. Nelson, Nathan Siemers, Suzanne J. Suchard, Joshua Finger, C. Gordon Todderud, Dana Banas
  • Identification and cloning of a novel human gene, RET16, involved in the intracellular signaling cascade
    Publication number: 20020187492
    Abstract: The present invention describes a newly discovered polynucleotide encoding a protein involved in the cell signaling cascade, called RET16, cloned, isolated and identified from TNF-alpha stimulated human microvascular endothelial cells, as well as mouse and rat RET16 orthologs thereof. Also described are the RET16 polypeptide sequence, expression vectors, host cells, agonists, antagonists, antisense molecules, and antibodies related to the polynucleotide and/or polypeptide of the present invention. Methods for screening for modulators, particularly inhibitors, of the human RET16 protein, and use of the RET16 polynucleotide and polypeptide for therapeutics and diagnostics are described.
    Type: Application
    Filed: February 15, 2002
    Publication date: December 12, 2002
    Inventors: C. Gordon Todderud, Joshua Finger, Jill Rillema