Patents by Inventor C. Grace Yeh

C. Grace Yeh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL FORMULATIONS USEFUL TO TREAT INFLAMMATORY AND IMMUNE DISORDERS
    Publication number: 20030008914
    Abstract: A pharmaceutical formulation is provided for the treatment of inflammatory and/or immune disorders, particularly those mediated by platelet activating factor (“PAF”) or a product of 5-lipoxygenase. The formulation, in one embodiment, is an essentially anhydrous ointment containing an active agent selected from the group consisting of 2,5-diaryl tetrahydrofurans, 2,5-diaryl tetrahydrothiophenes, 2,4-diaryl tetrahydrofurans, 2,4-diaryl tetrahydrothiophenes, 1,3-diaryl cyclopentanes, 2,4-diaryl pyrrolidines, and 2,5-diaryl pyrrolidines, and an enhancer composition containing one or more C3-18 esters such as diethyl succinate, propylene carbonate, diisopropyl adipate and glyceryl triacetate. In another embodiment, the formulation is a cream, gel, lotion, oil, or the like, containing the: active agent in crystalline form. The invention also encompasses the novel crystalline form of the active agent, and methods for using the formulations to treat individuals with inflammatory and/or immune disorders.
    Type: Application
    Filed: October 15, 1999
    Publication date: January 9, 2003
    Inventors: C. GRACE YEH, GORDON J. DOW, ROBERT W. LATHROP, MUKAND S. CHORGHADE, ALLA VERKATA RAMA RAO
  • Methods of inhibiting complement activation
    Patent number: 5851528
    Abstract: The present invention relates to novel chimeric proteins comprising a first polypeptide which inhibits complement activation, linked to a second polypeptide which inhibits complement activation, nucleic acids encoding novel chimeric proteins and methods of reducing inflammation with the administration of the chimeric proteins of the invention.
    Type: Grant
    Filed: July 3, 1997
    Date of Patent: December 22, 1998
    Assignee: Cytomed, Inc.
    Inventors: Jone-Long Ko, Paul J. Higgins, C. Grace Yeh
  • Chimeric proteins which block complement activation
    Patent number: 5679546
    Abstract: The present invention relates to novel chimeric proteins comprising a first polypeptide which inhibits complement activation, linked to a second polypeptide which inhibits complement activation, nucleic acids encoding novel chimeric proteins and methods of reducing inflammation with the administration of the chimeric proteins of the invention.
    Type: Grant
    Filed: September 22, 1994
    Date of Patent: October 21, 1997
    Assignee: Cytomed, Inc.
    Inventors: Jone-Long Ko, C. Grace Yeh