Abstract: A content mining system and process utilizes a combination of term recognition and rules-based activity-event classification, performed using a modular database that defines one or more vertical markets or information sectors, to identify sector relevant evidence. The primary elements of the identified evidence are scored in a manner that rates the relevance of a content item with respect to a set of identified nominative entities, a set of activity-based event categories, further associated as sets of entity-event pairs. A database constructed of the scored information provides a relevancy indexed repository of the original unstructured content items.

Abstract: This invention pertains to certain active carbamic acid compounds which inhibit HDAC activity and which have the following formula: (I) A is an aryl group; Q1 is a covalent bond or an aryl leader group; J is a sulfonamide linkage selected from: —S(?O)2NR1— and —NR1S(?O)2—; R1 is a sulfonamido substituent; and, Q2 is an acid leader group; with the proviso that if J is —S(?O)2NR1—, then Q1 is an aryl leader group; and pharmaceutically acceptable salts, solvates, amides, esters, ethers, chemically protected forms, and prodrugs thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HDAC, and, e.g., to inhibit proliferative conditions, such as cancer and psoriasis.