Abstract: A haptic actuator may include a housing that includes a ferromagnetic material having a first heat conductance, and a coil carried by the housing in a medial portion thereof and generating waste heat when electrically powered. The haptic actuator may also include a field member movable within the housing responsive to the coil. The field member may include at least one permanent magnet establishing a magnetic path with the housing. A heat spreading layer may be thermally coupled to the housing adjacent the coil. The heat spreading layer may have a second heat conductance greater than the first heat conductance to spread the waste heat from the coil to adjacent portions of the housing.

Abstract: The disclosed embodiments of haptic locomotion use one or more actuators to: 1) determine the properties of contact surfaces to improve various applications that use haptic locomotion; 2) automatically improve power transfer efficiency during wireless charging or cellular or wireless signal reception; 3) increase device accessibility for visually or hearing impaired users; 4) improve speaker and microphone performance; 5) protect a free falling mobile device from impact damage by orienting the mobile device to a low-risk orientation during free fall, or by driving the mobile device away from a high-risk orientation during free fall; and 6) control asymmetric surface friction using a directional magnetic field provided by an actuator to improve haptic locomotion in a desired direction of travel.

Abstract: Methods of reducing loading across a cartilaginous joint, or of reducing pain in a cartilaginous joint caused by cartilage damage in the joint. The methods involve implanting one or more magnetic devices in the bones, or affixing one or more magnetic devices onto the surface of the bones, that form the joint. For example, to reduce loading or reduce pain in a knee joint, one or more magnetic devices maybe implanted in the femur and in the tibia. The magnetic devices are oriented to generate a repulsive magnetic force between the one or more magnetic devices of each of the bones forming the joint.

Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.

Abstract: Disclosed are embodiments of magnetic virtual springs for haptic systems. In an embodiment, a haptic system comprises: a magnetic housing having a surface with a surface profile; a mechanical spring system disposed in the housing, the mechanical spring system including one or more mechanical springs; a mass disposed within the housing and mechanically coupled to the mechanical spring system, the mass including or coupled to a magnet, the surface profile causing a magnetic force component to be generated in at least one direction that varies with the magnet position, the magnetic force component combining with a mechanical force component provided by the mechanical springs.

Abstract: A bone screw comprising a shaft, in which the shaft comprises a bore that is configured to fit a magnet. In addition, a bone plate comprising apertures that can fit the bone screw. The bone plate may be fastened to bone using the bone screws, and the bone screws may be oriented to generate attractive or repulsive forces. Further, a disc-shaped housing that comprises a magnet.

Abstract: An intervertebral disc replacement device comprising a superior plate and an inferior plate, in which each plate contains one or more embedded magnets. The one or more magnets in the superior plate and the one or more magnet in the inferior plate are oriented such that a magnetic force exists between the one or more magnets in the superior plate and the one or more magnet in the inferior plate. In addition, an intervertebral disc replacement device comprising a superior plate and an inferior plate, in which each plate contains one or more embedded magnets, and the plates are designed to form an articulating surface. Further, an intervertebral disc replacement device comprising a superior plate, an inferior plate, and a spacer, in which each plate contains one or more embedded magnets, and the superior and inferior plates are designed to form articulating surfaces with the spacer.

Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.

Abstract: A magnetic screw device of a bone screw and one or more magnets that are attached to the bone screw. The bone screw may have a stem, which comprises a connector and at least one thread, and a housing assembly. The connector of the stem may be configured to articulate with the housing assembly such that the stem can rotate and angulate relative to the housing assembly. The magnetic screw device may be used to treat or stabilize spines with abnormal curvature, prevent further curvature progression, and relieve pain associated with abnormal curvature.

Abstract: A haptic actuator may include first and second bodies movable along an arcuate path of travel. The haptic actuator may also include a biasing member coupled between the first and second bodies. At least one electrical coil may be configured to move the first and second bodies to produce a haptic effect.

Abstract: A method of treating hypoxic tissue such as wound tissue comprises contacting a composition to the hypoxic tissue in a hypoxia-treatment effective amount, the composition comprising a biodegradable polymer and an inorganic peroxide incorporated into the polymer.

Abstract: A double helix actuator is disclosed that includes a double helix coil wound around a movable proof mass that is enclosed within a magnetic structure. The double helix coil and the magnetic structure are arranged relative to each other so that the magnetic field generated by the entirety of the double helix coil contributes to a linear force direction of the actuator. The double helix actuator produces a greater linear force density compared to traditional racetrack coil actuators, where only a portion of the coil contributes to the linear force. The double helix actuator also produces torque in addition to linear force which allows the double helix to provide unique haptic sensations in a variety of applications.

Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.

Abstract: A haptic actuator may include first and second bodies movable along an arcuate path of travel. The haptic actuator may also include a biasing member coupled between the first and second bodies. At least one electrical coil may be configured to move the first and second bodies to produce a haptic effect.

Abstract: A microfabrication process includes: (1) etching a shield pattern into a substrate; (2) forming a set of shielding layers on the substrate and in the shield pattern, wherein the shielding layers include n+1 magnetic layers and n spacing layers, n is 0 or an integer that is 1 or greater than 1, and each spacing layer is disposed between a pair of magnetic layers; and (3) planarizing the substrate to expose edges of the shielding layers.

Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.

Abstract: Stabilized trimers of a clade A strain and a clade C strain of HIV-1 are provided. Broadly neutralizing antisera against HIV-1, methods of making broadly neutralizing antisera against HIV-1, broadly neutralizing vaccines against HIV-1, as well as methods of treating subjects infected with HIV, preventing HIV infection, and inhibiting HIV-mediated activities are also provided.

Abstract: The disclosed embodiments of haptic locomotion use one or more actuators to: 1) determine the properties of contact surfaces to improve various applications that use haptic locomotion; 2) automatically improve power transfer efficiency during wireless charging or cellular or wireless signal reception; 3) increase device accessibility for visually or hearing impaired users; 4) improve speaker and microphone performance; 5) protect a free falling mobile device from impact damage by orienting the mobile device to a low-risk orientation during free fall, or by driving the mobile device away from a high-risk orientation during free fall; and 6) control asymmetric surface friction using a directional magnetic field provided by an actuator to improve haptic locomotion in a desired direction of travel.

Abstract: Prosthetic implant devices and related methods are provided. The prosthetic implant devices include an internal component and an external component. The internal component has an implant portion associated with one or more rare earth magnets. The internal component being of a size and shape suitable for surgical implantation into the residual limb of the amputee. The one or more rare earth magnets generate at least one magnetic field. The external component having a prosthetic piston associated with a plurality of magnetic elements and a prosthetic cup associated with a magnetic array. The magnet elements of the prosthetic piston being in adaptable magnetic association with the at least one magnetic field generated by the one or more rare earth magnets.

Abstract: A bone screw comprising a shaft, in which the shaft comprises a bore that is configured to fit a magnet. In addition, a bone plate comprising apertures that can fit the bone screw. The bone plate may be fastened to bone using the bone screws, and the bone screws may be oriented to generate attractive or repulsive forces. Further, a disc-shaped housing that comprises a magnet.