Patents by Inventor Céline AMARA

Céline AMARA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIFUNCTIONAL NATURAL KILLER (NK) CELL ENGAGERS BINDING TO NKp46 AND CD123
    Publication number: 20220213202
    Abstract: The present disclosure relates to multifunctional binding proteins comprising a first and a second antigen binding domains (ABDs) and all or part of an immunoglobulin Fc region or variant thereof, wherein the first ABD binds specifically to human CD123 and the second ABD binds specifically to human NKp46 and wherein all or part of the immunoglobulin Fc region or variant thereof to a human Fc-? receptor. The disclosure also relates to methods for making said binding proteins, compositions thereof, and their uses, including the treatment or prevention of proliferative disorders, including Acute Myeloid Leukemia (AML) and myelodysplastic syndromes (MDS).
    Type: Application
    Filed: December 30, 2021
    Publication date: July 7, 2022
    Inventors: Céline AMARA, Céline NICOLAZZI, Marielle CHIRON, Francis DUFFIEUX, Jochen BENINGA, Angela VIRONE-ODDOS, Laurent GAUTHIER, Ariane THIELENS, Benjamin ROSSI