Patents by Inventor Céline Crauste

Céline Crauste has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Uses of lipophenolic compounds
    Patent number: 11419841
    Abstract: The present invention relates to compound of formula (I): wherein R is O—R3 or R1 and R2 are identical or different and are each independently H, (C1-C6)alkyl, —CO—(C1-C21)alkyl or —CO—(C11-C21)alkenyl group, provided that at least one of R1 or R2 is H or (C1-C6)alkyl, R3 is a —CO—(C11-C21)alkyl or —CO—(C11-C21)alkenyl group, or its pharmaceutically acceptable salts, racemates, diastereoisomers, enantiomers, or mixtures thereof, for use in prevention and/or treatment of a disease or disorder linked to an exacerbated vascular, lymphatic or mucosal permeability.
    Type: Grant
    Filed: November 12, 2018
    Date of Patent: August 23, 2022
    Inventors: Céline Crauste, Joseph Vercauteren, Francisco Veas, Thierry Durand, Nicolas Blondeau
  • Lipophenol compounds and uses thereof
    Patent number: 11014947
    Abstract: The present invention relates to a compound of formula (I) wherein: i is 0 or 1; j is 0 or 1; k is 0 or 1; R1 and R2 are in particular H, (C1-C12)alkyl, or a group of formula C(O)R; R is a, linear or branched, alkyl radical, comprising at least 19 carbon atoms; R3 is H and k=0 when j=1; or, when j=0, R3 is —C(O)R or -L-C(O)R; L, U and L? are linkers; wherein, when j=0, at least one of the groups R1; R2 and R3 comprises a radical R.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: May 25, 2021
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER, UNIVERSITE D'AUVERGNE, UNIVERSITE DE MONTPELLIER
    Inventors: Philippe Brabet, David Cia, Laurent Guillou, Christian Hamel, Claire Vigor, Thierry Durand, Céline Crauste, Joseph Vercauteren
  • Lipophenolic Flavonoid Derivatives Useful To Reduce Carbonyl And Oxidative Stresses (COS)
    Publication number: 20210139447
    Abstract: The invention relates to compound of formula (I): in particular flavonoid derivatives (quercetin and catechin derivatives), for use in the prevention and/or the treatment of a disease or disorder involving both carbonyl and oxidative stresses.
    Type: Application
    Filed: July 12, 2019
    Publication date: May 13, 2021
    Applicants: Centre National de la Recherche Scientifique (CNRS), Universite De Montpellier, Ecole Nationale Superieure de Chimie, Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Céline Crauste, Espérance Moine, Philippe Brabet, Thierry Durand, Joseph Vercauteren
  • New Uses of Lipophenolic Compounds
    Publication number: 20200360334
    Abstract: The present invention relates to compound of formula (I): wherein R is O—R3 or R1 and R2 are identical or different and are each independently H, (C1-C6)alkyl, —CO—(C1-C21)alkyl or —CO—(C11-C21)alkenyl group, provided that at least one of R1 or R2 is H or (C1-C6)alkyl, R3 is a —CO—(C11-C21)alkyl or —CO—(C11-C21)alkenyl group, or its pharmaceutically acceptable salts, racemates, diastereoisomers, enantiomers, or mixtures thereof, for use in prevention and/or treatment of a disease or disorder linked to an exacerbated vascular, lymphatic or mucosal permeability.
    Type: Application
    Filed: November 12, 2018
    Publication date: November 19, 2020
    Applicants: Universite De Montpellier, Centre National de la Recherche Scientifique (CNRS), Ecole Nationale Superieure de Chimie, Institut de Recherche Pour le Developpement (IRD), Universite D'Aix-Marseille, Communaute Universites et Etablissements Universite Cote D Azur
    Inventors: Céline Crauste, Joseph Vercauteren, Fransisco Veas, Thierry Durand, Nicolas Blondeau
  • NEW LIPOPHENOL COMPOUNDS AND USES THEREOF
    Publication number: 20180273554
    Abstract: The present invention relates to a compound of formula (I) wherein:—i is 0 or 1; j is 0 or 1; k is 0 or 1;—R1 and R2 are in particular H, (C1-C12)alkyl, or a group of formula C(O)R;—R is a, linear or branched, alkyl radical, comprising at least 19 carbon atoms;—R3 is H and k=0 when j=1; or, when j=0, R3 is —C(O)R or -L-C(O)R;—L, U and L? are linkers; wherein, when j=0, at least one of the groups R1; R2 and R3 comprises a radical R.
    Type: Application
    Filed: May 7, 2018
    Publication date: September 27, 2018
    Inventors: Philippe BRABET, David CIA, Laurent GUILLOU, Christian HAMEL, Claire VIGOR, Thierry DURAND, Céline CRAUSTE, Joseph VERCAUTEREN
  • Lipophenol compounds and uses thereof
    Patent number: 10011620
    Abstract: The present invention relates to a compound of formula (I) wherein: i is 0 or 1; j is 0 or 1; k is 0 or 1; R1 and R2 are in particular H, (C1-C12)alkyl, or a group of formula C(O)R; R is a, linear or branched, alkyl radical, comprising at least 19 carbon atoms; R3 is H and k=0 when j=1; or, when j=0, R3 is —C(O)R or -L-C(O)R; L, U and L? are linkers; wherein, when j=0, at least one of the groups R1; R2 and R3 comprises a radical R.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: July 3, 2018
    Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER, UNIVERSITE D'AUVERGNE, UNIVERSITE DE MONTPELLIER
    Inventors: Philippe Brabet, David Cia, Laurent Guillou, Christian Hamel, Claire Vigor, Thierry Durand, Céline Crauste, Joseph Vercauteren
  • NEW LIPOPHENOL COMPOUNDS AND USES THEREOF
    Publication number: 20170037067
    Abstract: The present invention relates to a compound of formula (I) wherein: —i is 0 or 1; j is 0 or 1; k is 0 or 1; —R1 and R2 are in particular H, (C1-C12)alkyl, or a group of formula C(O)R; —R is a, linear or branched, alkyl radical, comprising at least 19 carbon atoms; —R3 is H and k=0 when j=1; or, when j=0, R3 is —C(O)R or -L-C(O)R; —L, U and L? are linkers; wherein, when j=0, at least one of the groups R1; R2 and R3 comprises a radical R.
    Type: Application
    Filed: April 24, 2015
    Publication date: February 9, 2017
    Inventors: Philippe BRABET, David CIA, Laurent GUILLOU, Christian HAMEL, Claire VIGOR, Thierry DURAND, Céline CRAUSTE, Joseph VERCAUTEREN
  • Method for preparing nucleotides and related analogues by synthesis on soluble substrate, and biological tools thus prepared
    Patent number: 8614312
    Abstract: The invention concerns a method for preparing monomer nucleotides or nucleotide analogues comprising the steps of: (1) coupling a soluble polyethylene glycol support provided with at least one diacid or ether-acid linker and a monomer nucleoside or nucleoside analogue to an amine group or hydroxyl group of the nucleoside with the aid of a coupling agent; (2) at least one step for phosphorylation of said nucleoside or nucleoside analogue coupled to said support with a phosphorylation agent; (3) cleavage of said support and recovery of at least one monomer nucleotide or nucleotide analogue. The nucleotides prepared are biological tools.
    Type: Grant
    Filed: February 23, 2009
    Date of Patent: December 24, 2013
    Assignees: Centre National de la Recherche Scientifique, Universite Montpellier 2 Sciences et Techniques
    Inventors: Suzanne Peyrottes, Christian Perigaud, Céline Crauste
  • METHOD FOR PREPARING NUCLEOTIDES AND RELATED ANALOGUES BY SYNTHESIS ON SOLUBLE SUBSTRATE, AND BIOLOGICAL TOOLS THUS PREPARED
    Publication number: 20110118454
    Abstract: The invention concerns a method for preparing monomer nucleotides or nucleotide analogues comprising the steps of: (1) coupling a soluble polyethylene glycol support provided with at least one diacid or ether-acid linker and a monomer nucleoside or nucleoside analogue to an amine group or hydroxyl group of the nucleoside with the aid of a coupling agent; (2) at least one step for phosphorylation of said nucleoside or nucleoside analogue coupled to said support with a phosphorylation agent; (3) cleavage of said support and recovery of at least one monomer nucleotide or nucleotide analogue. The nucleotides prepared are biological tools.
    Type: Application
    Filed: February 23, 2009
    Publication date: May 19, 2011
    Inventors: Suzanne Peyrottes, Christian Perigaud, Céline Crauste