Patents by Inventor Céline Jousse

Céline Jousse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDUCIBLE EXPRESSION CASSETTE, AND USES THEREOF
    Publication number: 20220040329
    Abstract: An expression cassette including a gene of interest under the control of an inducible promoter, characterized in that said inducible promoter includes at least one CARE regulatory sequence (C/EBP-ATF responsive element) and a minimal promoter. Also, a vector and a host cell, as well as to a pharmaceutical composition including such a cassette, and to the use thereof for treating diseases by gene therapy.
    Type: Application
    Filed: September 29, 2021
    Publication date: February 10, 2022
    Inventors: Pierre FAFOURNOUX, Alain BRUHAT, Celine JOUSSE, Anne-Catherine MAURIN, Julien AVEROUS
  • INDUCIBLE EXPRESSION CASSETTE, AND USES THEREOF
    Publication number: 20190224337
    Abstract: An expression cassette including a gene of interest under the control of an inducible promoter, characterized in that said inducible promoter includes at least one CARE regulatory sequence (C/EBP-ATF responsive element) and a minimal promoter. Also, a vector and a host cell, as well as to a pharmaceutical composition including such a cassette, and to the use thereof for treating diseases by gene therapy.
    Type: Application
    Filed: December 28, 2018
    Publication date: July 25, 2019
    Inventors: Pierre FAFOURNOUX, Alain BRUHAT, Celine JOUSSE, Anne-Catherine MAURIN, Julien AVEROUS
  • INDUCIBLE EXPRESSION CASSETTE, AND USES THEREOF
    Publication number: 20140322184
    Abstract: The invention relates to an expression cassette including a gene of interest under the control of an inducible promoter, characterized in that said inducible promoter includes at least one CARE regulatory sequence (C/EBP-ATF responsive element) and a minimal promoter. The invention also relates to a vector and a host cell, as well as to a pharmaceutical composition including such a cassette, and to the use thereof for treating diseases by gene therapy.
    Type: Application
    Filed: November 6, 2012
    Publication date: October 30, 2014
    Inventors: Pierre Farfournoux, Alain Bruhat, Celine Jousse, Anne-Catherine Maurin, Julien Averous
  • Methods of screening test compounds using GADD34L, an eIF2?-specific phosphatase subunit
    Patent number: 7097996
    Abstract: The invention is directed to methods and reagents for identifying test substances useful for the prevention or treatment of diseases involving an oxidative stress. The methods involve screening assays, including high throughput screening techniques, in which the test substances are tested for their ability to promote resistance to oxidative stress by inhibiting the activity of GADD34L, and thereby inhibiting the dephosphorylation of eIF2?, while not causing stress.
    Type: Grant
    Filed: August 28, 2003
    Date of Patent: August 29, 2006
    Assignee: New York University
    Inventors: David Ron, Céline Jousse
  • Methods of screening test compounds using GADD34L, an eIF2alpha-specific phosphatase subunit
    Publication number: 20040142345
    Abstract: The invention is directed to methods and reagents for identifying test substances useful for the prevention or treatment of diseases involving an oxidative stress. The methods involve screening assays, including high throughput screening techniques, in which the test substances are tested for their ability to promote resistance to oxidative stress by inhibiting the activity of GADD34L, and thereby inhibiting the dephosphorylation of eIF2&agr;, while not causing stress.
    Type: Application
    Filed: August 28, 2003
    Publication date: July 22, 2004
    Inventors: David Ron, Celine Jousse