Abstract: Warm-blooded animals are treated for Herpes simplex virus-I by administering to the animal a dosage, effective to alleviate the symptoms of the virus, of undecylenic acid and at least one pharmaceutically acceptable carrier, wherein the compound is in the range of from about 1 to about 95% by weight of the composition.

Abstract: Esters of 2-adamantanone oxime are prepared and are disclosed as possessing anti-inflammatory activity and antiviral activity against murine hepatitis virus.

Abstract: Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##STR1## wherein R and R.sup.1 each represent hydrogen; or R and R.sup.1 taken together form a second bond between the carbon atoms bearing R and R.sup.1 ; n is a positive whole integer of from 1 to 3; Y represents --CH.dbd.CH--, or ##STR2## with the proviso that when each of R and R.sup.1 represents hydrogen, Y represents --CH.dbd.CH, and when Y represents --CH.dbd.CH, n is equal to 1 or 2; and Z represents thienyl, phenyl, or substituted phenyl wherein the substituents on the substituted phenyl may be attached at the ortho, meta, or para positions of the phenyl ring and are selected from halogen, a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, a lower alkoxy group of from 1 to 4 carbon atoms, di(lower)-alkylamino, or a saturated monocyclic heterocyclic group such as pyrrolidino, piperidino, morpholino, or N-(lower)-alkylpiperazino.

Abstract: Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1##Wherein R represents hydrogen or hydroxy; R.sup.1 represents hydrogen; or R and R.sup.1 taken together form a second bond between the carbon atoms bearing R and R.sup.1 ; n is a positive whole integer of from 1 to 3; Z represents thienyl, phenyl, or substituted phenyl wherein the substituents on the substituted phenyl may be attached at the ortho, meta, or para positions of the phenyl ring and are selected from halogen, a straight or branched lower alkyl chain of from 1 to 4 carbon atoms, a lower alkoxy group of from 1 to 4 carbon atoms, di(lower)alkylamino, or a saturated monocyclic heterocyclic group such as pyrrolidino, piperidino, morpholino, or N-(lower)alkylpiperazino. Pharmaceutically acceptable acid addition salts and individual optical isomers of compounds of the above formula are also included as a part of this invention.

Abstract: Compounds of the following general formula are useful as antihistamine agents, antiallergy agents and bronchodilators: ##SPC1##Wherein R represents hydrogen or hydroxy; R.sup.1 represents hydrogen; or R and R.sup.1 taken together form a second bond between the carbon atoms bearing R and R.sup.1 ; n is the integer 4 or 5; Y represents ##EQU1## or ##EQU2## Z represents phenyl or a substituted phenyl ring wherein the substituent on the substituted phenyl ring is attached at the ortho, meta, or para position of the phenyl ring and is selected from halogen, a straight or branched alkyl group of from 1 to 6 carbon atoms, alkoxy of from 1 to 6 carbon atoms, cycloalkyl of from 3 to 6 carbon atoms, di(lower)alkylamino, or a saturated monocyclic heterocyclic group selected from pyrrolidino, piperidino, morpholino or N-(lower)alkyl-piperazino; and pharmaceutically acceptable acid addition salts and individual optical isomers.

Abstract: Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1##Wherein R.sup.1 represents cyclohexyl, phenyl, or substituted phenyl wherein the substituent on the substituted phenyl is selected from halogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or a lower alkoxy group of from 1 to 4 carbon atoms; R.sup.2 represents hydrogen or hydroxy; R.sup.3 represents hydrogen, or R.sup.2 and R.sup.3 taken together form a second bond between the carbon atoms bearing R.sup.2 and R.sup.

Abstract: Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1##Wherein R.sup.1 represents cyclohexyl, phenyl, or substituted phenyl wherein the substituent on the substituted phenyl is selected from halogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or a lower alkoxy group of from 1 to 4 carbon atoms; R.sup.2 represents hydrogen or hydroxy; R.sup.3 represents hydrogen; or R.sup.2 and R.sup.3 taken together form a second bond between the carbon atoms bearing R.sup.2 and R.sup.

Abstract: Warm-blooded animals are treated for Herpes simplex virus-I by administering to the animal a dosage, effective to alleviate the symptoms of the virus, of undecylenic acid and at least one pharmaceutically acceptable carrier, wherein the compound is in the range of from about 1 to about 95% by weight of the composition.