Patents by Inventor C. Thomas

C. Thomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12286654
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: April 29, 2025
    Assignee: Metagenomi, Inc.
    Inventors: Jyun-Liang Lin, Alan Brooks, Cristina Butterfield, Christopher Brown, Cindy Castelle, Brian C. Thomas
  • Patent number: 12272437
    Abstract: Systems and methods for maintaining an electronic health records system, including a server storing a medical records database. Requests for medical data for a patient in a master problem list are received from a user device, and appropriate list permissions are determined and granted for hierarchical derivative problem lists. Annotated data is received at the server from a user device based on annotations made to a derivative problem list, and problem lists are updated with the received annotated data in real time. The received annotated data is compared with current entries using natural language processing to detect duplicate entries, the duplicate entries are iteratively detected and removed from the master problem list, and non-duplicate entries are stored in authorized derivative problem lists based on the natural language processing and list update permissions for each of the derivative problem lists.
    Type: Grant
    Filed: April 29, 2024
    Date of Patent: April 8, 2025
    Assignee: Retrieve Medical, Inc.
    Inventors: Donald C. Thomas, III, Christopher E. Orlando
  • Publication number: 20250002886
    Abstract: Disclosed herein are engineered nucleases and nuclease systems, including chimeric nucleases and chimeric nuclease systems. Engineered and chimeric nucleases disclosed herein include nucleic acid guided nuclease. Additionally disclosed herein are methods of generating engineered nucleases and methods of using the same.
    Type: Application
    Filed: September 13, 2024
    Publication date: January 2, 2025
    Inventors: Brian C. Thomas, Alan Brooks, Christopher Brown, Cristina Noel Butterfield, Daniela S.A. Goltsman, Jyun-Liang Lin, Isabel Nocedal, Morayma Temoche-Diaz
  • Publication number: 20240415939
    Abstract: The present disclosure concerns methods and compositions for inhibiting replication of viruses within an organism in need thereof. In some cases, the methods and compositions can be applicable to aquacultured organisms. The aquacultured organisms can include, but are not limited to, crustacean organisms such as shrimp.
    Type: Application
    Filed: June 30, 2021
    Publication date: December 19, 2024
    Inventors: Arun Dhar, F. C. Thomas Allnutt, Roberto Cruz Flores
  • Patent number: 12163844
    Abstract: A LADOR circuit is in signal communication with a pixel array. The LADOR circuit is configured to generate an integrator reset voltage based on a resistance of the at least one heated bolometer pixel, and to detect laser energy incident on the at least one heated bolometer pixel based on a comparison between the integrator reset voltage and an input threshold voltage (Vthreshold).
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: December 10, 2024
    Assignee: RAYTHEON COMPANY
    Inventors: Jehyuk Rhee, Matthew C. Thomas, Henry Lee
  • Patent number: 12130185
    Abstract: A trigger sense circuit includes a pseudo-differential comparator circuit in signal communication with a pixel array. The pseudo-differential comparator circuit includes a first input in signal communication with a reference pixel group included in the pixel array to receive a pixel reference voltage, and a second input in signal communication with a target pixel group included in the pixel array to receive a pixel target voltage. The pseudo-differential comparator circuit is configured to selectively operate in a calibration mode to remove false trigger events and a comparison mode to detect at least one overheated pixel included in the target pixel group.
    Type: Grant
    Filed: August 19, 2021
    Date of Patent: October 29, 2024
    Assignee: RAYTHEON COMPANY
    Inventors: Jehyuk Rhee, Henry Lee, Matthew C. Thomas
  • Patent number: 12123700
    Abstract: Methods and systems of measurement for blown film lines are provided. The sensing system includes a terahertz (THz) sensor positioned adjacent to a film bubble extruded from a blown film die, and a sensor support configured to guide the THz sensor around the circumference of the film bubble to measure its film thickness.
    Type: Grant
    Filed: September 24, 2020
    Date of Patent: October 22, 2024
    Assignee: 3M Innovative Properties Company
    Inventors: Thomas J. Strey, David L. Hofeldt, Gregory J. McGill, Jay M. Krieger, Christopher J. Rother, Paul C. Thomas
  • Patent number: 12103994
    Abstract: Cationic copolymers having pendant N-allylimidazolium-containing groups are provided. The cationic copolymers can be used, for example, to provide anion exchange membranes for use in electrochemical cells such as fuel cells, electrolyzers, batteries, and electrodialysis cells. The anion exchange membranes typically have good mechanical properties and ionic conductivity.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: October 1, 2024
    Assignee: 3M Innovative Properties Company
    Inventors: Claire Hartmann-Thompson, Mark J. Pellerite, Marina M. Kaplun, John C. Thomas
  • Patent number: 12106056
    Abstract: One embodiment of the present invention sets forth a technique for analyzing a transcript of a structured interaction. The technique includes determining a first portion of the transcript that corresponds to a first dialogue act. The technique also includes matching the first portion of the transcript to a first component of a script for the structured interaction based on a first set of embeddings for the first portion of the transcript and a second set of embeddings associated with the first component of the script. The technique further includes causing a first mapping between the first portion of the transcript and the first component to be outputted.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: October 1, 2024
    Assignee: HIREGUIDE PBC
    Inventors: Jason T. Lam, Joel D. Young, Honglei Zhuang, Netanel Weizman, Scott C. Parish, Bryan N. Cavanagh, Christopher C. Cole, Alycia M. Damp, Eszter Fodor, Laura A. Kruizenga, Janice C. Oh, Rachel M. Policastro, Geoffrey C. Thomas, Gregory A. Walloch
  • Publication number: 20240288311
    Abstract: A LADOR circuit is in signal communication with a pixel array. The LADOR circuit is configured to generate an integrator reset voltage based on a resistance of the at least one heated bolometer pixel, and to detect laser energy incident on the at least one heated bolometer pixel based on a comparison between the integrator reset voltage and an input threshold voltage (Vthreshold).
    Type: Application
    Filed: November 10, 2021
    Publication date: August 29, 2024
    Inventors: Jehyuk Rhee, Matthew C. Thomas, Henry Lee
  • Publication number: 20240282418
    Abstract: Systems and methods for maintaining an electronic health records system, including a server storing a medical records database. Requests for medical data for a patient in a master problem list are received from a user device, and appropriate list permissions are determined and granted for hierarchical derivative problem lists. Annotated data is received at the server from a user device based on annotations made to a derivative problem list, and problem lists are updated with the received annotated data in real time. The received annotated data is compared with current entries using natural language processing to detect duplicate entries, the duplicate entries are iteratively detected and removed from the master problem list, and non-duplicate entries are stored in authorized derivative problem lists based on the natural language processing and list update permissions for each of the derivative problem lists.
    Type: Application
    Filed: April 29, 2024
    Publication date: August 22, 2024
    Inventors: Donald C. Thomas, III, Christopher E. Orlando
  • Patent number: 12018104
    Abstract: A crosslinkable copolymer is provided. The crosslinkable copolymer has pendant cationic nitrogen-containing groups with some, but not all, of these pendant groups further including a (meth)acryloyl group. The (meth)acryloyl groups can react to form a crosslinked copolymer that is ionically conductive. The crosslinked copolymer can be used to provide an anion exchange membrane that can be used in electrochemical cells such as fuel cells, electrolyzers, batteries, and electrodialysis cells.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: June 25, 2024
    Assignee: 3M Innovative Properties Company
    Inventors: Claire Hartmann-Thompson, Mark J. Pellerite, John C. Thomas, Marina M. Kaplun
  • Patent number: 12002557
    Abstract: Systems and methods for maintaining an electronic health records system, including a server storing a medical records database. Requests for medical data for a patient in a master problem list are received from a user device, and appropriate list permissions are determined and granted for hierarchical derivative problem lists. Annotated data is received at the server from a user device based on annotations made to a derivative problem list, and problem lists are updated with the received annotated data in real time. The received annotated data is compared with current entries using natural language processing to detect duplicate entries, the duplicate entries are iteratively detected and removed from the master problem list, and non-duplicate entries are stored in authorized derivative problem lists based on the natural language processing and list update permissions for each of the derivative problem lists.
    Type: Grant
    Filed: September 30, 2022
    Date of Patent: June 4, 2024
    Assignees: RETRIEVE MEDICAL, INC., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Donald C. Thomas, III, Christopher E. Orlando
  • Patent number: 11966474
    Abstract: Trusted execution of a workload payload is brokered among multiple trusted execution platforms. The workload payload is received from a source computing system and includes input data, trusted execution code, and one or more trusted execution policies. At least one of the multiple trusted execution platforms is selected based on the one or more trusted execution policies. A brokered payload is generated to include executable trusted execution code and the input data. The brokered payload is communicated to the selected at least one trusted execution platform. A brokered result generated from the brokered payload by the selected at least one trusted execution platform is received. A workload result based on the brokered result is returned to the source computing platform.
    Type: Grant
    Filed: November 1, 2021
    Date of Patent: April 23, 2024
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Stefan Thom, Brian Telfer, Deepu C. Thomas
  • Publication number: 20240112767
    Abstract: Systems and methods for maintaining an electronic health records system, including a server storing a medical records database. Requests for medical data for a patient in a master problem list are received from a user device, and appropriate list permissions are determined and granted for hierarchical derivative problem lists. Annotated data is received at the server from a user device based on annotations made to a derivative problem list, and problem lists are updated with the received annotated data in real time. The received annotated data is compared with current entries using natural language processing to detect duplicate entries, the duplicate entries are iteratively detected and removed from the master problem list, and non-duplicate entries are stored in authorized derivative problem lists based on the natural language processing and list update permissions for each of the derivative problem lists.
    Type: Application
    Filed: September 30, 2022
    Publication date: April 4, 2024
    Inventors: Donald C. Thomas, III, Christopher E. Orlando
  • Publication number: 20230348876
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: March 7, 2023
    Publication date: November 2, 2023
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Brian C. Thomas
  • Publication number: 20230348877
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: March 8, 2023
    Publication date: November 2, 2023
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Brian C. Thomas
  • Publication number: 20230230074
    Abstract: A method and system provided for a single-action with which the customer places an order and receives goods by the single action of connecting an electrical vehicle (EV) to a charging station according to the business terms associated with this invention, the affiliated organizations that purchase or support the operation of the invention participate in a business “franchise” operation whereby all affiliated organizations increase their revenues as the volume of EV charging events increases.
    Type: Application
    Filed: March 27, 2023
    Publication date: July 20, 2023
    Inventors: Paul S. Levy, Edward Butler, John C. Thomas
  • Publication number: 20230120926
    Abstract: U-splines are a novel approach to the construction of a spline basis for representing smooth objects in Computer-Aided Design (CAD) and Computer-Aided Engineering (CAE). A spline is a piecewise-defined function that satisfies continuity constraints between adjacent cells in a mesh. U-splines differ from existing spline constructions, such as Non-Uniform Rational B-splines (NURBS), subdivision surfaces, T-splines, and hierarchical B-splines, in that they can accommodate local variation in cell size, polynomial degree, and smoothness simultaneously over more varied mesh configurations. Mixed cell types (e.g., triangle and tetrahedron and quadrilateral and hexahedral cells in the same mesh) and T-junctions are also supported. The U-spline construction is presented for curves, surfaces, and volumes with higher dimensional generalizations possible. A set of requirements are given to ensure that the U-spline basis is positive, forms a partition of unity, is complete, and is locally linearly independent.
    Type: Application
    Filed: April 1, 2022
    Publication date: April 20, 2023
    Inventors: Derek C. Thomas, Michael A. Scott
  • Publication number: 20230056910
    Abstract: A trigger sense circuit includes a pseudo-differential comparator circuit in signal communication with a pixel array. The pseudo-differential comparator circuit includes a first input in signal communication with a reference pixel group included in the pixel array to receive a pixel reference voltage, and a second input in signal communication with a target pixel group included in the pixel array to receive a pixel target voltage. The pseudo-differential comparator circuit is configured to selectively operate in a calibration mode to remove false trigger events and a comparison mode to detect at least one overheated pixel included in the target pixel group.
    Type: Application
    Filed: August 19, 2021
    Publication date: February 23, 2023
    Inventors: Jehyuk Rhee, Henry Lee, Matthew C. Thomas