Abstract: A system, method, and apparatus are provided for dynamically managing toll charges for a vehicle which transmits one or more messages to a backend server of a toll service with vehicle location data and toll-related data collected from a memory storage device or one or more in-vehicle sensors which capture the toll-related data relating to the vehicle operation and design so that the backend server of the toll service can calculate one or more adjustments to a toll charge rate for the vehicle based on the toll-related data in the second message.

Abstract: A system, method, and apparatus are provided for dynamically enrolling a vehicle with a tolling authority by transmitting a vehicle toll service enrollment request message to a backend server of a toll managed services server (TMSS) upon detecting that the vehicle has entered onto a proximity corridor area associated with a toll road managed by the tolling authority, and then receiving a vehicle enrollment message from the TMSS after the TMSS determines that the vehicle is not enrolled with the tolling authority and displaying a vehicle enrollment message for viewing by an operator of the vehicle which invites an operator of the vehicle to enroll the vehicle with the tolling authority.

Abstract: A system, method, and apparatus are provided for dynamically managing road use charges for a vehicle which transmits one or more messages to a backend server of a road use charging (RUC) service with vehicle location data and RUC-related data collected from a memory storage device or one or more in-vehicle sensors which capture the RUC-related data relating to the vehicle operation and design so that the backend server of the RUC service can generate an RUC report which includes one or more adjustments to a RUC rate for the vehicle based on the RUC-related data in the second message.

Abstract: Injectable, biodegradable and removable polymer based drug suspension for ultra-long-acting drug delivery are disclosed. Ultra-long-acting in-situ forming implant (ISFI) drug suspension delivery systems as multipurpose prevention technologies for a multitude of applications are also provided. Methods of use, including treatment of subjects, using the disclosed compositions and ISFIs are also provided.

Abstract: Light emitting diodes with regrown semiconductor layers and methods of manufacture are described. In an embodiment, a light emitting diode includes a base structure including a first cladding layer doped with a first dopant type (e.g. n-type) and step surface. A mesa pillar including an active layer protrudes from the step surface, and a regrown second cladding layer doped with a second dopant type (e.g. p-type) is in direct contact with and spans a bottom surface and sidewalls of the mesa pillar and the step surface.

Abstract: Methods, systems, and apparatuses for remote well operation control. Methods include conducting, with a plurality of remote well operation control hosts operating on corresponding remote well logging data acquisition management systems, a well operation using a well operation system at a well, wherein the well operation system includes a carrier having disposed thereon at least one logging instrument. Methods may include establishing a first operational control relationship between the carrier and a first of the plurality of remote well operation control hosts sufficient for the first remote well operation control host to control the carrier; and establishing a second operational control relationship between a selected one of the at least one logging instrument and a second remote well operation control host different than the first, the operational control relationship sufficient for the second remote well operation control host to control the at least one logging instrument and receive logging data.

Abstract: The system includes an optical resonator, a mount, and a fastener. The optical resonator is comprised of a material with a horizontal plane symmetry. The optical resonator includes a horizontal plane protrusion for mounting. The horizontal plane protrusion includes discrete resonator rotational orientation positions. The mount comprises mounting legs compatible with the horizontal plane symmetry. The mount includes discrete mount rotational orientation positions that correspond to the discrete resonator rotation orientation positions at a plurality of rotational angles. The fastener secures the horizontal plane protrusion of the optical resonator to the mount.

Abstract: Augmented or synergized anti-inflammatory constructs are disclosed including anti-inflammatory terpenes and/or vanilloids covalently conjugated to one another so that the activity of the conjugate is greater than the sum of its parts. Also disclosed are methods of improving the potency of an anti-inflammatory terpene or vanilloid by linking it to another anti-inflammatory terpene or vanilloid via a carbamate linkage, where the potency of the conjugate is greater than the sum of its parts.

Abstract: Disclosed are various embodiments for presenting a user interface in association with video content features. A video content feature is rendered on at least one display. A current scene in the video content feature is determined. Cast members are determined who have appeared in the current scene from a beginning of the current scene up to a current time in the current scene. A user interface is rendered on at least one display. The user interface includes selectable cast member components that each include an image of a cast member, a name of the cast member, and a name of a respective character performed by the cast member.

Abstract: A method of autonomously controlling the ground speed of a harvester, such as a self-propelled or towed wind rower, uses both the engine speed and the header speed as control parameters to increase or decrease the ground speed as necessary to maintain efficient harvester operation over varying terrain and crop conditions. A control system includes a controller which receives signals from sensors indicative of engine speed, header speed and harvester ground speed and uses actuators to control the header speed, engine speed and harvester ground speed. An operator interface permits an operator to engage or disengage the autonomous mode of control system operation, as well as to directly control the harvester.

Abstract: A Vertical Cavity Surface Emitting Laser (VCSEL) including a light emitting III-nitride active region including quantum wells (QWs), wherein each of the quantum wells have a thickness of more than 8 nm, a cavity length of at least 7 ?, or at least 20 ?, where lambda is a peak wavelength of the light emitted from the active region, layers with reduced surface roughness, a tunnel junction intracavity contact. The VCSEL is flip chip bonded using In—Au bonding. This is the first report of a VCSEL capable of continuous wave operation.

Abstract: A system for managing prescriptions via a blockchain is provided. Prescription information relating to a the prescription is displayed. Submission information for the pharmacy relating to dispensing the prescription is displayed for each of a plurality of pharmacies. Selection of a pharmacy to dispense the prescription is received, where a prescription transaction relating to the prescription is recorded in a blockchain. An indication that a dose was taken is received from the patient after the prescription is dispensed by the selected pharmacy selected. A dose token transaction is recorded in the blockchain.

Abstract: A focused treatment tip (FTT) for controlling the evaporation rate and providing targeted delivery of low temperature liquified gases for contact with living tissue includes a contoured body. When filled with liquified gas, the device insulates the gas from waste heat sources, such as the surrounding environment. The device can control the evaporation rate of the liquified gas at the treatment site. The controlled evaporation rate affects the rate of heat transfer from the treated tissue allowing for controlled exposure times and desired outcomes. The device can be used with various application tips to further define the target tissue area to be treated while minimizing collateral damage to surrounding tissue and isolating the gas within the contoured body and focusing heat transfer to the desired treatment area. The device may use transparent materials that make the treatment visible to the operator while the liquified gas is evaporating.

Abstract: An agricultural planting machine includes a frame, a row unit supported by the frame, the row unit comprising a disk opener configured to create a furrow for planting agricultural material in a first row and a row cleaner disposed in a path of the disk opener and configured to move residue from the path. A residue shield is configured to shield a second row from the residue.

Abstract: A III-nitride optoelectronic device includes at least one n-type layer, an active region grown on or above the n-type layer, at least one p-type layer grown on or above the active region, and a tunnel junction grown on or above the p-type layer. A conductive oxide may be wafer bonded on or above the tunnel junction, wherein the conductive oxide comprises a transparent conductor and may contain light extraction features on its non-bonded face. The tunnel junction also enables monolithic incorporation of electrically-injected and optically-pumped III-nitride layers, wherein the optically-pumped III-nitride layers comprise high-indium-content III-nitride layers formed as quantum wells (QWs) that are grown on or above the tunnel junction. The optically-pumped high-indium-content III-nitride layers emit light at a longer wavelength than the electrically-injected III-nitride layers.

Abstract: A system for managing prescriptions via a blockchain is provided. The system records in the blockchain a prescription transaction that identifies a prescription that has been written for a patient. The system then records in the blockchain a submission selection transaction with code for controlling selection of a pharmacy to dispense the prescription. For pharmacies that provide a submission for dispensing the prescription, the system records in the blockchain a submission transaction with submission information relating to dispensing of the prescription by the pharmacy. When a pharmacy is selected to dispense the prescription, the system records in the blockchain a selected submission transaction indicating the pharmacy selected to dispense the prescription. When the prescription is dispensed, the system records in the blockchain a dispense transaction indicating that the selected pharmacy has dispensed the prescription.

Abstract: A channel-less microfluidic pump includes a cartridge including a substrate and an actuatable film layer disposed on the substrate, and a manifold having at least three actuatable void volumes separated by a plurality of wall sections and an actuatable flexible layer disposed on the manifold interfacing the actuatable film layer. In operation, the pump can be in an unactuated state wherein the actuatable film layer is disposed against the surface of the substrate or an actuated state wherein at least a portion of the flexible layer and a corresponding portion of the actuatable film layer are deflected into a corresponding void volume thus forming a fluidic volume between the deflected portion of the actuatable film layer and the surface of the substrate. In the actuated state, there is a fluidic gap between immediately adjacent void volumes formed by a thinned region of the flexible layer at a point of contact with a top surface of a wall section.

Abstract: The disclosure provides a method for treating a subject afflicted with a tumor comprising administering to the subject a therapeutically effective amount of an anti-PD-1 antibody or antigen-binding portion thereof or an anti-PD-L1 antibody or anti-gen-binding portion thereof, wherein the subject is identified as having a high inflammatory gene signature score and a tumor that has a high tumor mutation burden (TMB) status. In some embodiments, the high inflammatory gene signature score is determined by measuring the expression of a panel of inflammatory genes in a tumor sample obtained from the subject, wherein the inflammatory gene panel comprises CD274 (PD-L1), CD8A, LAG3, and STAT1.

Abstract: A hybrid growth method for III-nitride tunnel junction devices uses metal-organic chemical vapor deposition (MOCVD) to grow one or more light-emitting or light-absorbing structures and ammonia-assisted or plasma-assisted molecular beam epitaxy (MBE) to grow one or more tunnel junctions. Unlike p-type gallium nitride (p-GaN) grown by MOCVD, p-GaN grown by MBE is conductive as grown, which allows for its use in a tunnel junction. Moreover, the doping limits of MBE materials are higher than MOCVD materials. The tunnel junctions can be used to incorporate multiple active regions into a single device. In addition, n-type GaN (n-GaN) can be used as a current spreading layer on both sides of the device, eliminating the need for a transparent conductive oxide (TCO) layer or a silver (Au) mirror.

Abstract: A flip chip III-Nitride LED which utilizes a dielectric coating backed by a metallic reflector (e.g., aluminum or silver). High reflectivity and low resistance contacts for optoelectronic devices. Low ESD rating optoelectronic devices. A VCSEL comprising a tunnel junction for current and optical confinement.