Abstract: A thermal management system for a vehicle includes a first coolant circulation circuit including a first pump, a first electrical component, a second pump, and a second electrical component connected through a first coolant line. The system includes a first coolant connection line including a first end and a second end. The first end is connected to the first coolant line upstream of the first pump and the first electrical component and downstream of the second pump and the second electrical component. The second end is connected to the first coolant line downstream of the first pump and the first electrical component and upstream of the second pump and the second electrical component. The system includes an HVAC module and a heat exchanger disposed on the first coolant connection line. The heat exchanger is located inside the HVAC module to heat air introduced into the HVAC module using a coolant.

Abstract: This disclosure relates to methods for treating cancer in a subject identified as having chronic myelomonocytic leukemia (CMML), comprising administering an anti-ILT3 antigen binding protein, or antigen binding fragment to the patient every three weeks (Q3W).

Abstract: Disclosed in the present invention are a PLpro protease inhibitor, and a preparation method and application thereof. The PLpro protease inhibitor can be combined with one or more pharmaceutically acceptable auxiliary materials or one or more other active ingredients to serve as a PLpro inhibitor to treat diseases caused by or diseases related to virus infection. The auxiliary material can be a carrier, a diluent, an adhesive, a lubricant, a wetting agent, etc. The protease inhibitor has high inhibitory activity, and can be used for broad-spectrum antivirals, especially for coronaviruses, for example, HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU, SARS-CoV, MERS-CoV, SARS-CoV-2, etc., in particular SARS-CoV, MERS-CoV, SARS-CoV-2.

Abstract: This disclosure relates to methods for treating cancer in a subject identified as having acute myeloid leukemia (AML), comprising administering an anti-ILT3 antigen binding protein, or antigen binding fragment to the patient every three weeks (Q3W).

Abstract: In a method and an apparatus for controlling heating of a vehicle battery, the method includes: obtaining, by a receiver, an ambient temperature of a vehicle and battery output power; determining, by a controller, whether the ambient temperature is lower than a predetermined ambient temperature threshold; when it is determined that the ambient temperature is lower than the predetermined ambient temperature threshold, determining, by the controller, whether a battery heating setting is on; and when it is determined that the battery heating setting is on, controlling, by the controller, the heating of the vehicle battery so that the battery output power is between a first reference power and a second reference power.

Abstract: This disclosure relates to methods for treating solid tumors in a patient identified as having metastatic triple negative breast cancer, glioblastoma, metastatic pancreatic ductal adenocarcinoma, metastatic soft tissue sarcoma, or metastatic non-squamous non-small cell lung carcinoma, comprising administering an anti-ILT3 antigen binding protein, or antigen binding fragment, and an anti-PD1 antigen binding protein, or antigen binding fragment, to the patient every three weeks (Q3W).