Patents by Inventor Caihong Zhou

Caihong Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SALT OF ALDOSE REDUCTASE INHIBITOR, AND PREPARATION METHOD AND APPLICATION THEREOF
    Publication number: 20220127273
    Abstract: The present invention sets forth a salt of an aldose reductase inhibitor shown in formula A-N. The salt being able to be prepared as a crystal form, having notably improved solubility relative to the compound of formula A, having lower hygroscopicity allowing for stable existence, and thus being more easily made into a medicine than are the formula A compound or other salts.
    Type: Application
    Filed: February 28, 2020
    Publication date: April 28, 2022
    Inventors: Zhankun YANG, Hanyu YANG, Pengfei LI, Xiaopeng LIU, Caihong ZHOU, Junling WANG, Chunna LI, Xibao LIU
  • Prevention, diagnosis and treatment of cancer overexpressing GPR160
    Patent number: 10865415
    Abstract: Provided are a dsRNA construct of an orphan G-protein-coupled receptor GPR160 gene related to prostate cancer and the use thereof, wherein the dsRNA construct of the GPR160 gene and a composition thereof can prevent or treat prostate cancer.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: December 15, 2020
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Caihong Zhou, Xinchuan Dai, Mingwei Wang
  • PREVENTION, DIAGNOSIS AND TREATMENT OF CANCER OVEREXPRESSING GPR160
    Publication number: 20190055565
    Abstract: Provided are a dsRNA construct of an orphan G-protein-coupled receptor GPR160 gene related to prostate cancer and the use thereof, wherein the dsRNA construct of the GPR160 gene and a composition thereof can prevent or treat prostate cancer.
    Type: Application
    Filed: September 29, 2016
    Publication date: February 21, 2019
    Applicant: Shanghai Institute of Material Medica, Chinese Academy of Sciences
    Inventors: Caihong Zhou, Xinchuan Dai, Mingwei Wang
  • Substituted cyclic compound, its preparation process and its medical use
    Patent number: 8039492
    Abstract: The present invention provides a substituted cyclic compound of the following general formula I or II: its preparation process and its use as a glucagon-like peptide-1 receptor regulator for preventing or treating metabolic disorders including, but not limited to, diabetes, insulin resistance and obesity, etc.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: October 18, 2011
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Mingwei Wang, Na Li, Xin Xie, Qing Liu, Caihong Zhou, Fajun Nan, Guangxing Wang
  • Glucagon-like peptide-1 receptor agonists, the preparation and the use of the same
    Patent number: 7838682
    Abstract: The present invention provides the glucagon-like peptide-1 receptor agonists. It is indicated that the agonists have good binding capability to glucagon-like peptide-1 receptor by pharmacological tests. The present invention also provides the preparation of the agonists.
    Type: Grant
    Filed: December 25, 2003
    Date of Patent: November 23, 2010
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Fajun Nan, Mingwei Wang, Wenlong Wang, Caihong Zhou
  • SUBSITUTED CYCLIC COMPOUND, ITS PREPARATION PROCESS AND ITS MEDICAL USE
    Publication number: 20100168183
    Abstract: The present invention provides a substituted cyclic compound of the following general formula I or II: its preparation process and its use as a glucagon-like peptide-1 receptor regulator for preventing or treating metabolic disorders including, but not limited to, diabetes, insulin resistance and obesity, etc.
    Type: Application
    Filed: June 21, 2006
    Publication date: July 1, 2010
    Applicant: Shanghai Institute of Materia Medica, Chinese Academy of Science
    Inventors: Mingwei Wang, Na Li, Xin Xie, Qing Liu, Caihong Zhou, Fajun Nan
  • Non-steroidal androgen receptor modulators, preparation process, pharmaceutical composition and use thereof
    Patent number: 7737288
    Abstract: Non-steroidal androgen receptor modulating compounds of the general formula (I), their pharmaceutically acceptable salts, preparation process and pharmaceutically compositions containing the said compounds are disclosed. Such compounds of the general formula (I) or their pharmaceutically acceptable salts can be used for preparing non-steroidal medicines to treat and/or prevent conditions or diseases such as prostatic hyperplasia, prostate cancer, hirsutism, severe hormone-dependent alopecia or acne, etc. as a result of androgen receptor antagonistic activities.
    Type: Grant
    Filed: May 26, 2006
    Date of Patent: June 15, 2010
    Assignees: Shanghai Institute of Materia Medica Chinese Academy of Sciences, Sichuan University
    Inventors: Mingwei Wang, Caihong Zhou, Xin Hui, Haoran Su, Jie Gao, Yong Deng, Dacheng Yang
  • Non-Steroidal Androgen Receptor Modulators, Preparation Process, Pharmaceutical Composition and Use Thereof
    Publication number: 20080293808
    Abstract: Non-steroidal androgen receptor modulating compounds of the general formula (I), their pharmaceutically acceptable salts, preparation process and pharmaceutically compositions containing the said compounds are disclosed. Such compounds of the general formula (I) or their pharmaceutically acceptable salts can be used for preparing non-steroidal medicines to treat and/or prevent conditions or diseases such as prostatic hyperplasia, prostate cancer, hirsutism, severe hormone-dependent alopecia or acne, etc. as a result of androgen receptor antagonistic activities.
    Type: Application
    Filed: May 26, 2006
    Publication date: November 27, 2008
    Inventors: Mingwei Wang, Caihong Zhou, Xin Hui, Haoran Su, Jie Gao, Yong Deng, Dacheng Yang
  • Glucagon-like peptide-1 receptor agonists, the preparation and the use of the same
    Publication number: 20070043093
    Abstract: The present invention provides the glucagon-like peptide-1 receptor agonists. It is indicated that the agonists have good binding capability to glucagon-like peptide-1 receptor by pharmacological tests. The present invention also provides the preparation of the agonists.
    Type: Application
    Filed: December 25, 2003
    Publication date: February 22, 2007
    Inventors: Fajun Nan, Mingwei Wang, Wenlong Wang, Caihong Zhou