Abstract: Aspects of the disclosure include bodily lumen reshaping and reduction systems, devices and methods. Such implants can include a plurality of anchors serially interconnected with a cinching member. Delivery devices of the disclosure are configured to deploy a first anchor into tissue. The delivery device can then deploy a second anchor and wind the cinching member around the second anchor to reduce a distance between the first and second anchors, placating the tissue between the anchors. Additional anchors can be similarly deployed and the cinching member can be similarly adjusted to reshape the lumen. Methods of deploying and reshaping a bodily lumen are also disclosed. In various examples, the bodily lumen is a heart valve, atrial appendage, portion of a gastrointestinal tract or urethra. Various embodiments include one or more anchors having a ratchet assembly or the like to substantially prevent the cinching member from unwinding.

Abstract: Aspects include a system that includes an annuloplasty device having a plurality of segments. Each segment includes first and second ends, a flexible body, a pawl at the second end, and a plurality of teeth positioned along the body. At least ones of the pawls and teeth are engaged in a manner such that the plurality of segments form a closed loop. The system can further include a pull wire releasably secured to at least one of the plurality of segments. Methods of reducing dimensions of an annulus, such as a mitral valve annulus, using the systems of the disclosure are also disclosed.