Patents by Inventor Caitlin M. GUENTHER

Caitlin M. GUENTHER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AUTOMATED PRODUCTION OF VIRAL VECTORS
    Publication number: 20240026306
    Abstract: The present disclosure provides an automated method of producing viral vectors, utilizing engineered viral vector-producing cell lines within a fully-enclosed cell engineering system. Exemplary viral vectors that can be produced include lentivirus vectors, adeno-associated virus vectors, baculovirus vectors and retrovirus vectors.
    Type: Application
    Filed: June 20, 2023
    Publication date: January 25, 2024
    Inventors: Matthew HEWITT, Young SHIN, Bingnan GU, Caitlin M. GUENTHER, Anandita SETH
  • ADENO-ASSOCIATED VIRUS (AAV) PRODUCER CELL LINE AND RELATED METHODS
    Publication number: 20240018545
    Abstract: The present disclosure relates to a mammalian cell line for producing adeno-associated virus (AAV), suitably including nucleic acids encoding helper genes and AAV genes, under the control of derepressible promoters. The disclosure also relates to isolated nucleic acid molecules that encode such genes, as well as methods of using the mammalian cells for producing AAVs.
    Type: Application
    Filed: July 14, 2023
    Publication date: January 18, 2024
    Inventors: Bingnan GU, Caitlin M. GUENTHER, Anandita SETH
  • Adeno-associated virus (AAV) producer cell line and related methods
    Patent number: 11739347
    Abstract: The present disclosure relates to a mammalian cell line for producing adeno-associated virus (AAV), suitably including nucleic acids encoding helper genes and AAV genes, under the control of derepressible promoters. The disclosure also relates to isolated nucleic acid molecules that encode such genes, as well as methods of using the mammalian cells for producing AAVs.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: August 29, 2023
    Assignee: LONZA WALKERVILLE, INC.
    Inventors: Bingnan Gu, Caitlin M. Guenther, Anandita Seth
  • Automated production of viral vectors
    Patent number: 11718833
    Abstract: The present disclosure provides an automated method of producing viral vectors, utilizing engineered viral vector-producing cell lines within a fully-enclosed cell engineering system. Exemplary viral vectors that can be produced include lentivirus vectors, adeno-associated virus vectors, baculovirus vectors and retrovirus vectors.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: August 8, 2023
    Assignee: LONZA WALKERSVILLE, INC.
    Inventors: Matthew Hewitt, Young Shin, Bingnan Gu, Caitlin M. Guenther, Anandita Seth
  • AUTOMATED PRODUCTION OF VIRAL VECTORS
    Publication number: 20200208121
    Abstract: The present disclosure provides an automated method of producing viral vectors, utilizing engineered viral vector-producing cell lines within a fully-enclosed cell engineering system. Exemplary viral vectors that can be produced include lentivirus vectors, adeno-associated virus vectors, baculovirus vectors and retrovirus vectors.
    Type: Application
    Filed: December 19, 2019
    Publication date: July 2, 2020
    Inventors: Matthew HEWITT, Young SHIN, Bingnan GU, Caitlin M. GUENTHER, Anandita SETH
  • ADENO-ASSOCIATED VIRUS (AAV) PRODUCER CELL LINE AND RELATED METHODS
    Publication number: 20200199627
    Abstract: The present disclosure relates to a mammalian cell line for producing adeno-associated virus (AAV), suitably including nucleic acids encoding helper genes and AAV genes, under the control of derepressible promoters. The disclosure also relates to isolated nucleic acid molecules that encode such genes, as well as methods of using the mammalian cells for producing AAVs.
    Type: Application
    Filed: December 18, 2019
    Publication date: June 25, 2020
    Inventors: Bingnan GU, Caitlin M. GUENTHER, Anandita SETH