Patents by Inventor Caitlin MAIKAWA

Caitlin MAIKAWA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS
    Publication number: 20250051502
    Abstract: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
    Type: Application
    Filed: June 26, 2024
    Publication date: February 13, 2025
    Inventors: Eric A. Appel, Caitlin Maikawa, Joseph L. Mann
  • Polymer excipients for biopharmaceutical formulations
    Patent number: 12187828
    Abstract: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
    Type: Grant
    Filed: March 31, 2023
    Date of Patent: January 7, 2025
    Assignee: The Board of Trustees of the Leland Stanford Junior Univeristy
    Inventors: Eric A. Appel, Caitlin Maikawa, Joseph L. Mann
  • Polymer excipients for biopharmaceutical formulations
    Patent number: 12077621
    Abstract: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
    Type: Grant
    Filed: October 17, 2023
    Date of Patent: September 3, 2024
    Assignee: The Board of Trustees of the Leland Stanford Junior Univeristy
    Inventors: Eric A. Appel, Caitlin Maikawa, Joseph L. Mann
  • Polymer excipients for biopharmaceutical formulations
    Patent number: 11945892
    Abstract: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
    Type: Grant
    Filed: October 7, 2022
    Date of Patent: April 2, 2024
    Assignee: The Board of Trustees of the Leland Stanford Junior Univeristy
    Inventors: Eric A. Appel, Caitlin Maikawa, Joseph L. Mann
  • POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS
    Publication number: 20240067767
    Abstract: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
    Type: Application
    Filed: October 17, 2023
    Publication date: February 29, 2024
    Inventors: Eric A. APPEL, Caitlin MAIKAWA, Joseph L. Mann
  • POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS
    Publication number: 20230235109
    Abstract: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
    Type: Application
    Filed: March 31, 2023
    Publication date: July 27, 2023
    Inventors: Eric A. APPEL, Caitlin MAIKAWA, Joseph L. Mann
  • POLYMER EXCIPIENTS FOR BIOPHARMACEUTICAL FORMULATIONS
    Publication number: 20230108947
    Abstract: A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes.
    Type: Application
    Filed: October 7, 2022
    Publication date: April 6, 2023
    Inventors: Eric A. APPEL, Caitlin MAIKAWA, Joseph L. Mann
  • STABLE MONOMERIC INSULIN FORMULATIONS ENABLED BY SUPRAMOLECULAR PEGYLATION OF INSULIN ANALOGUES
    Publication number: 20230001013
    Abstract: Stable monomeric insulin formulations are enabled by supramolecular PEGylation of insulin or insulin analogues, and provide a method for treating diabetes, or managing or reducing blood glucose.
    Type: Application
    Filed: December 14, 2020
    Publication date: January 5, 2023
    Inventors: Eric A. APPEL, Caitlin MAIKAWA, Anton Allen Abbotsford SMITH
  • CO-FORMULATIONS OF AMYLIN ANALOGUES WITH INSULIN ANALOGUES FOR TREATMENT OF DIABETES
    Publication number: 20220125886
    Abstract: Compositions and methods for treating diabetes are disclosed. In particular, the invention relates to co-formulations of amylin analogues with insulin analogues for treatment of diabetes.
    Type: Application
    Filed: February 12, 2020
    Publication date: April 28, 2022
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Eric A. APPEL, Bruce A. BUCKINGHAM, David M. MAAHS, Caitlin MAIKAWA, Gillie Agmon ROTH