Abstract: Systems, methods, and programs for privately and securely providing accurate machine learning models to anonymous clients for various applications. Discrete model classes of models are trained on non-anonymous datasets at a centralized server and served to anonymous clients. Clients validate each model against its own localized datasets and retain the most accurate model. Clients improve their model locally through transfer learning on new datasets, and share the updated, anonymized parameters with a centralized computer. The centralized server aggregates and updates model parameters for each respective discrete model class. The improved models may be served to future and existing clients.

Abstract: Embodiments of the inventive concept include a portable ion concentration apparatus including a controller, a storage section to store one or more data samples, an amplifier circuit, and a chemical field effect transistor (CHEMFET). The CHEMFET and the amplifier circuit can indicate a quantity of nitrate levels in a sample media or a reference media. The controller can process the indication of the quantity of nitrate levels, and generate the one or more data samples based at least on the indication of the quantity of nitrate levels. The portable ion concentration apparatus can include an in-field analysis apparatus, an in-field measurement apparatus, or an in-soil monitoring apparatus. A measurement logic section can determine an ion concentration based on a sensitivity slope M or a polynomial fit. Also disclosed is a method for measuring ion concentration with a standard deviation correction.

Abstract: Embodiments of the inventive concept include a portable ion concentration apparatus including a controller, a storage section to store one or more data samples, an amplifier circuit, and a chemical field effect transistor (CHEMFET). The CHEMFET and the amplifier circuit can indicate a quantity of nitrate levels in a sample media or a reference media. The controller can process the indication of the quantity of nitrate levels, and generate the one or more data samples based at least on the indication of the quantity of nitrate levels. The portable ion concentration apparatus can include an in-field analysis apparatus, an in-field measurement apparatus, or an in-soil monitoring apparatus. A measurement logic section can determine an ion concentration based on a sensitivity slope M or a polynomial fit. Also disclosed is a method for measuring ion concentration with a standard deviation correction.

Abstract: Disclosed herein are host or receptor compounds that bind targets of interest. In one embodiment the compounds bind ions, such as metal ions. A compound, or a protonate or salt thereof, having the formula of: Formula IIa wherein R6 is an aminoalkoxy, alkylamino, nitro or —NH2; n is 1 or 2; each R2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; a is 0 to 4.

Abstract: Embodiments include a method for securing a membrane material to a gate of a molecular receptor-based chemical field-effect transistor (CHEMFET). The method can include casting a membrane material onto an exposed region of the gate, curing the membrane material, placing the CHEMFET into a mold, inserting a single application of impervious electrically insulative resin into the mold, and securing edges of the membrane material by the single application of the impervious electrically insulative resin, thereby physically preventing lifting off of the membrane material from the gate. Embodiments include a sensor module. The sensor module can include a CHEMFET, an amplifier circuit, one or more sensor pins for contacting field ground soil, a data logger, and a wireless transceiver, among other components.

Abstract: Embodiments of the inventive concept include a portable ion concentration apparatus including a controller, a storage section to store one or more data samples, an amplifier circuit, and a chemical field effect transistor (CHEMFET). The CHEMFET and the amplifier circuit can indicate a quantity of nitrate levels in a sample media or a reference media. The controller can process the indication of the quantity of nitrate levels, and generate the one or more data samples based at least on the indication of the quantity of nitrate levels. The portable ion concentration apparatus can include an in-field analysis apparatus, an in-field measurement apparatus, or an in-soil monitoring apparatus. A measurement logic section can determine an ion concentration based on a sensitivity slope M or a polynomial fit. Also disclosed is a method for measuring ion concentration with a standard deviation correction.

Abstract: Embodiments include a method for securing a membrane material to a gate of a molecular receptor-based chemical field-effect transistor (CHEMFET). The method can include casting a membrane material onto an exposed region of the gate, curing the membrane material, placing the CHEMFET into a mold, inserting a single application of impervious electrically insulative resin into the mold, and securing edges of the membrane material by the single application of the impervious electrically insulative resin, thereby physically preventing lifting off of the membrane material from the gate. Embodiments include a sensor module. The sensor module can include a CHEMFET, an amplifier circuit, one or more sensor pins for contacting field ground soil, a data logger, and a wireless transceiver, among other components.

Abstract: Embodiments include a method for securing a membrane material to a gate of a molecular receptor-based chemical field-effect transistor (CHEMFET). The method can include casting a membrane material onto an exposed region of the gate, curing the membrane material, placing the CHEMFET into a mold, inserting a single application of impervious electrically insulative resin into the mold, and securing edges of the membrane material by the single application of the impervious electrically insulative resin, thereby physically preventing lifting off of the membrane material from the gate. Embodiments include a sensor module. The sensor module can include a CHEMFET, an amplifier circuit, one or more sensor pins for contacting field ground soil, a data logger, and a wireless transceiver, among other components.

Abstract: A compound, or a protonate or salt thereof, having the formula of: wherein R1 is an optionally substituted aromatic group; n is 1 or 2; each R2 is independently selected from an optionally substituted alkyl, halogen, optionally substituted alkoxy, optionally substituted carboxyl, or amide; a is 0 to 4; R3 is H or an optionally substituted alkyl; each R4 and R5 is independently selected from H, optionally substituted alkyl, acyl, optionally substituted aralkyl, optionally substituted aryl, or —C(O)R8; and R8 is H, alkyl, aralkyl or aryl.

Abstract: Embodiments include a method for securing a membrane material to a gate of a molecular receptor-based chemical field-effect transistor (CHEMFET). The method can include casting a membrane material onto an exposed region of the gate, curing the membrane material, placing the CHEMFET into a mold, inserting a single application of impervious electrically insulative resin into the mold, and securing edges of the membrane material by the single application of the impervious electrically insulative resin, thereby physically preventing lifting off of the membrane material from the gate. Embodiments include a sensor module. The sensor module can include a CHEMFET, an amplifier circuit, one or more sensor pins for contacting field ground soil, a data logger, and a wireless transceiver, among other components.

Abstract: A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl.

Abstract: A compound, or a salt thereof, having the formula wherein Y is n is 1 or 2; each R is independently H, alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl; R1 is H, lower alkyl or aralkyl; R2 is selected from H, acyl, aralkyl, phosphonyl, —SO2R3; —C(O)R5; —C(O)OR7 or —C(O)NR9R10; R3; R5; R7; R9 and R10 independently are selected from H, lower alkyl, aralkyl or aryl; and R20 is selected from alkyl, substituted alkyl, a polyether moiety, carboxyl, substituted carboxyl, carbamate, substituted carbonate, carbonyloxy, alkoxy, substituted alkoxy, haloalkyl, halogen, nitro, amino, aryloxy, cyano, hydroxyl, or sulfonyl.