Patents by Inventor Calude Malvy

Calude Malvy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligonucleotides containing an antisense sequence stabilized by a secondary structure, pharmaceutical compositions containing them and method of blocking gene expression using them
    Patent number: 7022832
    Abstract: Oligonucleotides capable of modifying or inhibiting in vivo or in vitro expression of a target gene wherein the oligonucleotide has an antisense sequence, at least one secondary structure, and optionally a supplementary nucleotide sequence located at one and/or both ends of the antisense sequence and wherein the secondary structure disintegrates upon attachment of the oligonucleotide to a target nucleic acid; a pharmaceutical composition containing such an oligonucleotide as an active ingredient; and a method of treatment using such an oligonucleotide.
    Type: Grant
    Filed: September 7, 2001
    Date of Patent: April 4, 2006
    Assignees: Bioalliance Pharma (S.A.), Centre National de la Recherche Scientifique - CNRS
    Inventors: Calude Malvy, Valerie Helin, Andrei Maksimenko, Marina Gottikh
  • Oligonucleotides containing an antisense sequence stabilized by a secondary structure, pharmaceutical compositions containing them and method of blocking gene expression using them
    Publication number: 20020156261
    Abstract: Oligonucleotides capable of modifying or inhibiting in vivo or in vitro expression of a target gene wherein the oligonucleotide has an antisense sequence, at least one secondary structure, and optionally a supplementary nucleotide sequence located at one and/or both ends of the antisense sequence and wherein the secondary structure disintegrates upon attachment of the oligonucleotide to a target nucleic acid; a pharmaceutical composition containing such an oligonucleotide as an active ingredient; and a method of treatment using such an oligonucleotide.
    Type: Application
    Filed: September 7, 2001
    Publication date: October 24, 2002
    Inventors: Calude Malvy, Valerie Helin, Andrei Maksimenko, Marina Gottikh