Patents by Inventor Calvin Hobel

Calvin Hobel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Caspase inhibitors in the treatment of infection-associated preterm delivery
    Patent number: 8828950
    Abstract: Apoptotic processes induced by infection of, or injury to, fetal and placental tissues have been implicated in preterm delivery. Thus, modulation of apoptotis constitutes a strategy for improving pregnancy outcome in women with intrauterine infections. Caspase inhibitors, including the pancaspase inhibitor Z-VAD-FMK, can be used to prevent apoptosis and, thus, prevent preterm delivery. Accordingly, compositions and methods comprising caspase inhibitors for prevention of preterm delivery are provided.
    Type: Grant
    Filed: May 1, 2008
    Date of Patent: September 9, 2014
    Assignee: Cedars-Sinai Medical Center
    Inventors: Ozlem Equils, Calvin Hobel, Charles F. Simmons
  • CASPASE INHIBITORS IN THE TREATMENT OF INFECTION-ASSOCIATED PRETERM DELIVERY
    Publication number: 20100292174
    Abstract: Apoptotic processes induced by infection of, or injury to, fetal and placental tissues have been implicated in preterm delivery. Thus, modulation of apoptotis constitutes a strategy for improving pregnancy outcome in women with intrauterine infections. Caspase inhibitors, including the pancaspase inhibitor Z-VAD-FMK, can be used to prevent apoptosis and, thus, prevent preterm delivery. Accordingly, compositions and methods comprising caspase inhibitors for prevention of preterm delivery are provided.
    Type: Application
    Filed: May 1, 2008
    Publication date: November 18, 2010
    Applicant: CEDARS-SINAI MEDICAL CENTER
    Inventors: Ozlem Equils, Calvin Hobel, Charles F. Simmons