Abstract: An oral appliance includes: 1) a body defining a channel to accommodate an upper dentition; and 2) a motion sensor. The body includes a front portion defining a recess, and the motion sensor is affixed to the front portion.

Abstract: A toilet assembly with a self-cleaning rim system is provided. The toilet assembly includes a toilet tank for storing water used by the toilet assembly. The toilet assembly includes a flush valve disposed within the toilet tank that opens and closes to deliver the stored water in the toilet tank. The toilet assembly includes a toilet bowl comprising a rim having a hollow section and a top surface forming an area suitable for water flow. The toilet assembly includes a rinse channel including a rinse channel inlet for receiving water from the toilet tank, the rinse channel configured to deliver the water for cleaning the top surface of the rim with each activation of the flush valve.

Abstract: A method of displaying secondary content on secondary screen devices, comprising the steps: providing a primary screen content that is displayed on a theater screen; providing secondary screen devices that contain or have access to secondary screen content that is played in synchronicity with the primary screen content. The secondary screen content may include content that is available to all at a specific time point in the movie and content that is only available to users that have earned the right to watch the content. The earned content may be content that is integral and contextual to the primary screen content. Preferably, the earned content may be additional information, plot, or anagnorisis content that is not available in the primary screen content.

Abstract: An oral appliance includes: 1) a body defining a channel to accommodate an upper dentition; and 2) a motion sensor. The body includes a front portion defining a recess, and the motion sensor is affixed to the front portion.

Abstract: A system is disclosed for generating scores related to interactions with a revenue generator. A historical dataset corresponding to a historical behavior of a set of revenue generators may be identified. The historical dataset may be processed to identify a feature vector. A classifier model may be generated from the historical dataset and the feature vector. Current revenue generator data representing a current revenue generator may be collected. The current revenue generator data may be processed to generate a current revenue generator feature vector. A score may be generated by applying the classifier model to the current revenue generator data feature vector.

Abstract: A system is disclosed for generating scores related to interactions with a service provider partner. A historical dataset corresponding to a historical behavior of a set of service provider partners may be identified. The historical dataset may be processed to identify a feature vector. A classifier model may be generated from the historical dataset and the feature vector. Current service provider partner data representing a current service provider partner may be collected. The current service provider partner data may be processed to generate a current service provider partner feature vector. A score may be generated by applying the classifier model to the current service provider partner data feature vector.

Abstract: A system is disclosed for generating scores related to interactions with a service provider partner. A historical dataset corresponding to a historical behavior of a set of service provider partners may be identified. The historical dataset may be processed to identify a feature vector. A classifier model may be generated from the historical dataset and the feature vector. Current service provider partner data representing a current service provider partner may be collected. The current service provider partner data may be processed to generate a current service provider partner feature vector. A score may be generated by applying the classifier model to the current service provider partner data feature vector.

Abstract: A system is disclosed for monitoring a revenue generator. A historical dataset corresponding to a historical behavior of a set of revenue generators may be identified. The historical dataset may be processed to identify a feature vector relating to detecting a fraudulent revenue generator. A classifier model may be generated from the historical dataset and the feature vector. Current revenue generator data representing a current revenue generator may be collected. The current revenue generator data may be processed to generate a current revenue generator feature vector. A score representing the likelihood that the revenue generator is fraudulent may be generated by applying the classifier model to the current revenue generator data feature vector. A monitor may be identified and notified of the score of the current revenue generator. The monitor may perform some action based on the score of the current revenue generator.

Abstract: A system is disclosed for monitoring a service provider partner. A historical dataset corresponding to a historical behavior of a set of service provider partners may be identified. The historical dataset may be processed to identify a feature vector relating to detecting a fraudulent service provider partner. A classifier model may be generated from the historical dataset and the feature vector. Current service provider partner data representing a current service provider partner may be collected. The current service provider partner data may be processed to generate a current service provider partner feature vector. A score representing the likelihood that the service provider partner is fraudulent may be generated by applying the classifier model to the current service provider partner data feature vector. A monitor may be identified and notified of the score of the current service provider partner. The monitor may perform some action based on the score of the current service provider partner.

Abstract: A system for generating scores related to interactions with a revenue generator. A historical dataset corresponding to a historical behavior of a set of revenue generators may be identified. The historical dataset may be processed to identify a feature vector. A classifier model may be generated from the historical dataset and the feature vector. Current revenue generator data representing a current revenue generator may be collected. The current revenue generator data may be processed to generate a current revenue generator feature vector. A score may be generated by applying the classifier model to the current revenue generator data feature vector.

Abstract: Methods and compositions are provided for the protection of normal cells from cytoreductive therapy that target proliferating cells, by administering an inhibitor of Wnt signaling pathways. Wnt signaling is critically important for homeostasis of the epithelial lining of the adult intestine and other proliferating normal adult tissues.

Abstract: The present invention provides a method for inhibiting undesired angiogenesis including tumor-associated angiogenesis. The invention further provides a method for increasing the number of red blood cells or hematocrit in the circulation in subjects in need thereof. The invention also provides a method for simultaneously treating low hematocrit and undesired angiogenesis. Additionally, the present invention provides a method for determining efficacy or endpoint of treatment with one or more VEGF-inhibitors.

Abstract: These results indicate the efficacy of systemic expression of secreted Wnt antagonists as a general strategy for conditional inactivation of Wnt signaling in adult organisms, and illustrate a striking reliance on a single growth factor pathway for the maintenance of the architecture of the adult small intestine and colon. These results also indicate the potential utility of administration of Wnt pathway agonists for mucosal repair of the small intestine or colon.

Abstract: The present invention provides a method for inhibiting undesired angiogenesis including tumor-associated angiogenesis. The invention further provides a method for increasing the number of red blood cells or hematocrit in the circulation in subjects in need thereof. The invention also provides a method for simultaneously treating low hematocrit and undesired angiogenesis. Additionally, the present inventio provides a method for determining efficacy or endpoint of treatment with one or more VEGF-inhibitors.

Abstract: The present invention concerns a method, apparatus, and article of manufacture which provides an efficient way to change the function of a programmable logic unit included in a control device--where the control device manages the operational characteristics of a hardware unit--without having to disable system access to the hardware unit during the updating process. The hardware unit remains fully functional throughout execution of the updating method. To perform the update, the hardware unit must be connected to a host system by at least two communication channels. Each communication channel includes a control device including a programmable logic unit. The programmable logic unit is pre-programmed by a first data set which establishes its predetermined operational characteristics. Upgrading the programmable logic unit is accomplished by logically removing one of the communication channels leading from the host system to the hardware unit.