Patents by Inventor Calvin L. Keeler

Calvin L. Keeler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene encoding glycoprotein B of Infectious Laryngotracheitis Virus
    Patent number: 5443831
    Abstract: An isolated nucleic acid molecule encoding the gB glycoprotein of Infectious Laryngotracheitis Virus is disclosed. Also disclosed is incorporation of the gB gene into recombinant avipox virus for a vaccine used to immunize fowl.
    Type: Grant
    Filed: November 19, 1993
    Date of Patent: August 22, 1995
    Assignee: University of Delaware
    Inventors: Calvin L. Keeler, David J. Poulsen
  • Gene encoding cytadhesin protein of mycoplasma gallisepticum and its use
    Patent number: 5378820
    Abstract: The nucleic acid encoding the membrane-associated cytadhesin protein of M. gallisepticum is disclosed, together with the amino acid sequence of the encoded product. The nucleic acid sequence finds utility as a probe for M. gallisepticum DNA to diagnose M. gallisepticum infection in poultry. Expression of fragments of the nucleic acid sequence into polypeptide is also disclosed.
    Type: Grant
    Filed: November 9, 1992
    Date of Patent: January 3, 1995
    Inventors: Calvin L. Keeler, John E. Dohms
  • Recombinant infectious laryngotracheitis virus
    Patent number: 5279965
    Abstract: The present invention is concerned with the preparation of an Infectious Laryngotracheitis Virus (ILTV) mutant which does not produce a functional thymidine kinase enzyme as a result of a mutation in the TK gene, and its preparation.The invention also relates to an ILTV mutant containing a heterologous gene encoding an antigen of an avian pathogen incorporated into the TK gene. Such an ILTV mutant can be applied as a vector vaccine to induce an immune response after infection of an appropriate host animal.
    Type: Grant
    Filed: April 5, 1991
    Date of Patent: January 18, 1994
    Inventor: Calvin L. Keeler, Jr.