Abstract: Systems and methods for automatically determining a beam parameter at each of a plurality of treatment nodes are disclosed. The beam parameter may include a beam shape, beam size and/or beam orientation. Systems and methods for automatically selecting multiple collimators in a radiation treatment system are also disclosed.

Abstract: Intraoperative image(s) of a patient target site are generated by an intraoperative imaging system (e.g., ultrasound or X-ray). The intraoperative imaging system is tracked with respect to the patient target site and surgical instrument(s) (e.g., a pointer, endoscope or other intraoperative video or optical device). The intraoperative images, surgical instruments, and patient target site are registered into a common coordinate system. Spatial feature(s) of the patient target site are indicated on the images of the patient target site. Indicia relating the position and orientation of the surgical instrument(s) to the spatial feature(s) of the patient target site are projected on the images, with the indicia being used to correlate the position and orientation of the surgical instruments with respect to the target feature.