Patents by Inventor Cam MROSKE

Cam MROSKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Replication capable rAAV vectors encoding inhibitory siRNA and methods of their use
    Patent number: 10370662
    Abstract: In some embodiments, an antiviral vector is provided. The antiviral vector includes a replication competent adeno-associated virus (AAV) and an inhibitory expression cassette that includes a nucleotide sequence that encodes an RNAi molecule that inhibits expression of a targeted helper virus (THV) gene. The THV gene may be part of an Adenovirus (Ad) genome, a Human Papillomavirus (HPV) genome, a Human Herpes Virus (HHV) genome, or a Vaccinia virus (VV) genome.
    Type: Grant
    Filed: October 9, 2017
    Date of Patent: August 6, 2019
    Assignee: CITY OF HOPE
    Inventors: Kamehameha K. Wong, Jr., Cam Mroske, Saswati Chatterjee
  • REPLICATION CAPABLE rAAV VECTORS ENCODING INHIBITORY siRNA AND METHODS OF THEIR USE
    Publication number: 20180030449
    Abstract: In some embodiments, an antiviral vector is provided. The antiviral vector includes a replication competent adeno-associated virus (AAV) and an inhibitory expression cassette that includes a nucleotide sequence that encodes an RNAi molecule that inhibits expression of a targeted helper virus (THV) gene. The THV gene may be part of an Adenovirus (Ad) genome, a Human Papillomavirus (HPV) genome, a Human Herpes Virus (HHV) genome, or a Vaccinia virus (VV) genome.
    Type: Application
    Filed: October 9, 2017
    Publication date: February 1, 2018
    Inventors: Kamehameha K. WONG, Cam MROSKE, Saswati CHATTERJEE
  • Replication capable rAAV vectors encoding inhibitory siRNA and methods of their use
    Patent number: 9783805
    Abstract: In some embodiments, an antiviral vector is provided. The antiviral vector includes a replication competent adeno-associated virus (AAV) and an inhibitory expression cassette that includes a nucleotide sequence that encodes an RNAi molecule that inhibits expression of a targeted helper virus (THV) gene. The THV gene may be part of an Adenovirus (Ad) genome, a Human Papillomavirus (HPV) genome, a Human Herpes Virus (HHV) genome, or a Vaccinia virus (W) genome.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: October 10, 2017
    Assignee: CITY OF HOPE
    Inventors: Kamehameha K. Wong, Jr., Cam Mroske, Saswati Chatterjee
  • REPLICATION CAPABLE rAAV VECTORS ENCODING INHIBITORY siRNA AND METHODS OF THEIR USE
    Publication number: 20140256799
    Abstract: In some embodiments, an antiviral vector is provided. The antiviral vector includes a replication competent adeno-associated virus (AAV) and an inhibitory expression cassette that includes a nucleotide sequence that encodes an RNAi molecule that inhibits expression of a targeted helper virus (THV) gene. The THV gene may be part of an Adenovirus (Ad) genome, a Human Papillomavirus (HPV) genome, a Human Herpes Virus (HHV) genome, or a Vaccinia virus (W) genome.
    Type: Application
    Filed: February 28, 2014
    Publication date: September 11, 2014
    Inventors: Kamehameha K. WONG, JR., Cam MROSKE, Saswati CHATTERJEE