Patents by Inventor Camelia Birsan

Camelia Birsan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neuronal MORT1 isoforms
    Patent number: 6248875
    Abstract: A MORT1 gene initially cloned from HeLa cells and identified as a member of the receptor mediated apoptotic pathway, is expressed in the human neuronal cell line, NTERA2. Isolation of the MORT1 from this cell line revealed a transcript isoform that differed from the known MORT1 sequence by a deletion of 21 base pairs (bp 172-192 of the coding sequence). Cloning of MORT1 from adult human brain revealed two isoforms, one similarly deleted for bp 172-192, the other with a basepair substitution, A for G at position 173. Assessment of MORT1 function in a yeast two hybrid system indicates that the deleted and intact forms of MORT1 differ in their capacity to interact with other members of the apoptotic pathway.
    Type: Grant
    Filed: April 22, 1998
    Date of Patent: June 19, 2001
    Assignee: American Home Products Corporation
    Inventors: Andrew T. Wood, Brendan William Bingham, Kathleen H. Young, Camelia Birsan